Results 41 to 50 of about 97,118 (179)

Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain

open access: yesMolecular Pain, 2009
Background We previously reported that intrathecal injection of lysophosphatidylcholine (LPC) induced neuropathic pain through activation of the lysophosphatidic acid (LPA)-1 receptor, possibly via conversion to LPA by autotaxin (ATX).
Aoki Junken   +6 more
doaj   +1 more source

Plasma concentrations of lysophosphatidic acid and the expression of its receptors in peripheral blood mononuclear cells are altered in patients with cocaine use disorders

open access: yesTranslational Psychiatry, 2023
We have recently reported alterations in the plasma concentrations of lysophosphatidic acid (LPA) in patients with substance use disorders. In order to further explore the potential role of the LPA signaling system as biomarker in cocaine use disorders ...
María Flores-López   +12 more
doaj   +1 more source

Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma

open access: yesRespiratory Research, 2009
Background Lysophosphatidic acid (LPA) plays a critical role in airway inflammation through G protein-coupled LPA receptors (LPA1-3). We have demonstrated that LPA induced cytokine and lipid mediator release in human bronchial epithelial cells.
Chun Jerold   +7 more
doaj   +1 more source

High density lipoproteins with differing apolipoproteins: relationships to postprandial lipemia, cholesteryl ester transfer protein, and activities of lipoprotein lipase, hepatic lipase, and lecithin: cholesterol acyltransferase.

open access: yesJournal of Lipid Research, 1994
To gain insight into metabolic determinants of high density lipoproteins (HDL) containing apolipoproteins A-I and A-II (LpA-I/A-II) and those containing A-I, but devoid of A-II (LpA-I), the plasma concentration of LpA-I and LpA-I/A-II within the HDL2 and
H O Mowri   +5 more
doaj   +1 more source

Local Edge Betweenness based Label Propagation for Community Detection in Complex Networks

open access: yes, 2017
Nowadays, identification and detection community structures in complex networks is an important factor in extracting useful information from networks.
Bagheri, Alireza, Shahrivari, Hamid
core   +1 more source

High Expression of Lysophosphatidic Acid Induces Nerve Injury in LSS Patients via AKT Mediated NF-κB p65 Pathway

open access: yesFrontiers in Pharmacology, 2021
Lumbar spinal stenosis (LSS) is a spinal degenerative disease, complicated with nerve injury. Lysophosphatidic acid (LPA), a kind of glycerophospholipid molecule is elevated in the initial stages of neural injury.
Guiliang Zhai, Wenfei Liang, Yongjun Xu
doaj   +1 more source

Beam Scraping in the SPS for LHC Injection: Efficiency and Robustness Studies [PDF]

open access: yes, 2008
The Large Hadron Collider (LHC) at CERN will be the world's most powerful accelerator when it is commissioned in fall 2008. Operation of the LHC will require injection of very high intensity beams. Fast transverse beam scrapers have been installed in the
Letnes, Paul/LPA
core  

Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade. [PDF]

open access: yes, 2020
Saturated fatty acids (SFAs) (the "bad" fat), especially palmitate (PA), in the human diet are blamed for potential health risks such as obesity and cancer because of SFA-induced lipotoxicity. However, epidemiological results demonstrate a latent benefit
Candas-Green, Demet   +9 more
core  

Laser and electron deflection from transverse asymmetries in laser-plasma accelerators. [PDF]

open access: yes, 2019
We report on the deflection of laser pulses and accelerated electrons in a laser-plasma accelerator (LPA) by the effects of laser pulse front tilt and transverse density gradients.
Benedetti, Carlo   +11 more
core   +1 more source

Enhancing adult hippocampal neurogenesis with lysophosphatidic acid: a proposal for erasing cocaine contextual memory [PDF]

open access: yes, 2018
Stimulating adult hippocampal neurogenesis (AHN) has been uncovered as a promising approach in the manipulation of retrograde memories. This work aims to study whether increasing AHN with lysophosphatidic acid (LPA, an endogenous lysophospholipid with ...
Castilla Ortega, María Estela   +9 more
core  

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