Results 51 to 60 of about 113,253 (324)

Efficacy of cartridge-based nucleic acid amplification test (CBNAAT) in comparison with line probe assay and liquid culture in the evaluation of tubercular lymph node abscess

Journal of Family Medicine and Primary Care
Background: Tuberculosis (TB) remains the number one cause of adult deaths by a curable infectious disease. Mycobacterium tuberculosis bacilli (MTB) is the most common causative organism isolated from mycobacterial lymphadenitis.
Veena Reddy Vankayala, Sumeeth Sutrave, B Swapna Kumari, Ramulu Gaddam, Gopala Krishna Murthy Mandapakala   +4 more
doaj   +1 more source

Introduction to Coastal HF Maritime Surveillance Radars

Polish Maritime Research, 2019
This paper presents the main technical characteristics and working performances of coastal maritime surveillance radars, such as low-power High-Frequency Surface Wave Radars (HFSWR) and Over the Horizon Radars (OTHR). These radars have demonstrated to be
Ilcev Dimov Stojce
doaj   +1 more source

AntLP: ant-based label propagation algorithm for community detection in social networks

CAAI Transactions on Intelligence Technology, 2019
In social network analysis, community detection is one of the significant tasks to study the structure and characteristics of the networks. In recent years, several intelligent and meta-heuristic algorithms have been presented for community detection in ...
Razieh Hosseini, Alireza Rezvanian
doaj   +1 more source

The autotaxin-lysophosphatidic acid pathway emerges as a therapeutic target to prevent liver cancer

Molecular & Cellular Oncology, 2017
Using transcriptome meta-analysis, we recently identified the autotaxin (ATX)-lysophosphatidic acid (LPA) pathway as a regulator of hepatocellular carcinoma (HCC) risk in human cirrhosis patients.
Derek J. Erstad, Andrew M. Tager, Yujin Hoshida, Bryan C. Fuchs   +3 more
doaj   +1 more source

Coupled Electrostatic and Hydrophobic Destabilisation of the Gelsolin-Actin Complex Enables Facile Detection of Ovarian Cancer Biomarker Lysophosphatidic Acid

Biomolecules, 2023
Lysophosphatidic acid (LPA) is a promising biomarker candidate to screen for ovarian cancer (OC) and potentially stratify and treat patients according to disease stage. LPA is known to target the actin-binding protein gelsolin which is a key regulator of
Katharina Davoudian, Shayon Bhattacharya, Damien Thompson, Michael Thompson   +3 more
doaj   +1 more source

Compositional analyses of the associations between sedentary time, different intensities of physical activity, and cardiometabolic biomarkers among children and youth from the United States [PDF]

, 2019
Introduction : Compositional data analysis is one appropriate method for co-dependent data, even when data are collected for a subdivision of the 24-hour period, such as the waking day.
Carson, Valerie, Chaput, Jean-Philippe, Chastin, Sebastien, McGregor, Duncan, Tremblay, Mark S.   +4 more
core   +2 more sources

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism[S]

Journal of Lipid Research, 2018
Autotaxin (ATX) is an adipokine that generates the bioactive lipid, lysophosphatidic acid (LPA). ATX-LPA signaling has been implicated in diet-induced obesity and systemic insulin resistance.
Kenneth D'souza, Carine Nzirorera, Andrew Cowie, G. Varghese, P. Trivedi, Thomas O. Eichmann, D. Biswas, M. Touaibia, A. Morris, V. Aidinis, D. Kane, T. Pulinilkunnil, Petra C. Kienesberger   +12 more
semanticscholar   +1 more source

Cooperation of Gq, Gi, and G12/13 in Protein Kinase D Activation and Phosphorylation Induced by Lysophosphatidic Acid [PDF]

, 2003
To examine the contribution of different G-protein pathways to lysophosphatidic acid (LPA)-induced protein kinase D (PKD) activation, we tested the effect of LPA on PKD activity in murine embryonic cell lines deficient in Galpha q/11 (Galpha q/11 KO ...
Gu, Jennifer, Rozengurt, Enrique, Slice, Lee W., Yuan, Jingzhen   +3 more
core  

A comprehensive map of single-base polymorphisms in the hypervariable LPA kringle IV type 2 copy number variation region

Journal of Lipid Research, 2018
Lipoprotein (a) [Lp(a)] concentrations are among the strongest genetic risk factors for cardiovascular disease and present pronounced interethnic and interindividual differences.
S. Coassin, S. Schönherr, H. Weissensteiner, G. Erhart, L. Forer, J. L. Losso, C. Lamina, M. Haun, G. Utermann, B. Paulweber, Günther Specht, F. Kronenberg   +11 more
semanticscholar   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source