Results 81 to 90 of about 113,253 (324)

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA. [PDF]

PLoS ONE, 2012
Lysophosphatidic acid (LPA) mediates diverse cellular responses through the activation of at least six LPA receptors--LPA(1-6,) but the interacting proteins and signaling pathways that mediate the specificity of these receptors are largely unknown.
Tal Varsano, Vanessa Taupin, Lixia Guo, Oscar Y Baterina, Marilyn G Farquhar   +4 more
doaj   +1 more source

Study of Resistive Switching Dynamics and Memory States Equilibria in Analog Filamentary Conductive‐Metal‐Oxide/HfOx ReRAM via Compact Modeling

Advanced Electronic Materials, EarlyView.
A physics‐based compact model for Conductive‐Metal‐Oxide/HfOx ReRAM, accounting for ion dynamics, electronic conduction, and thermal effects, is presented. Accurate and versatile simulations of analog non‐volatile conductance modulation and memory state stabilization enable reliable circuit‐level studies, advancing the optimization of neuromorphic and ...
Matteo Galetta, Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Stephan Menzel, Antonio La Porta, Tommaso Stecconi, Folkert Horst, Bert Jan Offrein, Valeria Bragaglia   +9 more
wiley   +1 more source

In vivo metabolism of apolipoprotein A-I on high density lipoprotein particles LpA-I and LpA-I,A-II.

Journal of Lipid Research, 1991
Apolipoprotein (apo) A-I is the major protein in high density lipoproteins (HDL) and is found in two major subclasses of lipoproteins, those containing apolipoprotein A-II (termed LpA-I,A-II) and those without apoA-II (termed LpA-I). The in vivo kinetics
DJ Rader, G Castro, LA Zech, JC Fruchart, HB Brewer, Jr   +4 more
doaj   +1 more source

Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. [PDF]

, 2012
The pluripotent nature of human embryonic stem cells (hESCs) makes them convenient for deriving therapeutically relevant cells. Here we show using Wnt reporter hESC lines that the cells are heterogeneous with respect to endogenous Wnt signalling activity.
Ardehali, Reza, Blauwkamp, Timothy A, Nigam, Shelly, Nusse, Roel, Weissman, Irving L   +4 more
core   +1 more source

Neighborhood social environments and mental health among youth and adults in public housing

American Journal of Community Psychology, EarlyView.
Abstract Neighborhoods influence health in part through social processes. However, little is known about how multiple neighborhood social processes co‐occur, or about within (vs. between) neighborhood variation in social processes and health. This study asked how residents of a large public housing development describe their neighborhood and used ...
Jane Leer, Lindsay Lanteri, Rebekah Levine Coley, Samantha Teixeira   +3 more
wiley   +1 more source

Structural and functional differences of subspecies of apoA-I-containing lipoprotein in patients with plasma cholesteryl ester transfer protein deficiency.

Journal of Lipid Research, 1995
ApoA-I-containing lipoproteins exist in plasma in two main forms: one contains only apoA-I (LpA-I) while the other contains both apoA-I and apoA-II (LpA-I/A-II).
T Ohta, R Nakamura, K Takata, Y Saito, S Yamashita, S Horiuchi, I Matsuda   +6 more
doaj   +1 more source

On the Analysis of a Label Propagation Algorithm for Community Detection [PDF]

, 2012
This paper initiates formal analysis of a simple, distributed algorithm for community detection on networks. We analyze an algorithm that we call \textsc{Max-LPA}, both in terms of its convergence time and in terms of the "quality" of the communities ...
Kothapalli, Kishore, Pemmaraju, Sriram V., Sardeshmukh, Vivek   +2 more
core  

Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus

Nature Communications, 2016
Timely generation and normal maturation of ependymal cells along the aqueduct are critical for preventing physical blockage between the third and fourth ventricles and the development of fetal non-communicating hydrocephalus.
Raehee Park, Uk Yeol Moon, J. Y. Park, Lucinda J. Hughes, Randy L. Johnson, Seo-Hee Cho, Seonhee Kim   +6 more
semanticscholar   +1 more source

A systematic review of second language (L2) student writers' metacognitive experiences

British Educational Research Journal, EarlyView.
Abstract This systematic review synthesises empirical evidence on second language (L2) student writers' metacognitive experiences (MEs) across different classroom‐based L2 learning contexts in peer‐reviewed academic journals. A comprehensive search of six databases (Scopus, APA PsycINFO, British Education Index, ERIC subscription, Education Source and ...
Zhe Li, Jing Wu, Allen Thurston, Joanne O'Keeffe   +3 more
wiley   +1 more source