Results 61 to 70 of about 9,759 (160)

Lysophosphatidic Acid (LPA) Induces Plasma Exudation and Histamine Release in Mice via LPA Receptors

Journal of Pharmacological Sciences, 2006
.: Lysophosphatidic acid (LPA), the simplest of the water-soluble phospholipids, can evoke various biological responses. The present study examined the activity of LPA to induce plasma exudation and histamine release in mice.
Terumasa Hashimoto, Hisayuki Ohata, Kazuo Honda   +2 more
doaj   +1 more source

Interleukin-1β Expression Is Required for Lysophosphatidic Acid-Induced Lymphangiogenesis in Human Umbilical Vein Endothelial Cells

International Journal of Inflammation, 2011
Lysophosphatidic acid (LPA) is a lipid mediator which binds to G-protein-coupled receptors and regulates various cellular responses, including inflammation of endothelial cells.
Chih-Hsin Lin, JenHer Lu, Hsinyu Lee
doaj   +1 more source

Uncovering unique roles of LPA receptors in the tumor microenvironment. [PDF]

Receptors Clin Investig, 2015
Lee SC, Fujiwara Y, Tigyi GJ.
europepmc   +1 more source

The role of lysophosphatidic acid metabolism in castration-resistant prostate cancer progression. [PDF]

Front Oncol
Feng J, Liu J, He Y.
europepmc   +1 more source

Lysophosphatidic Acid Reduces Ischemic Brain Injury by Attenuating Vascular Permeability Through LPA4 Receptor Signaling. [PDF]

Transl Stroke Res
Yamada S, Takara K, Hosoe N, Shimizu A, Hayashi Y, Lynda L, Sonoda T, Kikuta K, Kidoya H.   +8 more
europepmc   +1 more source

The Antidepressant Amitriptyline Upregulates ERK1/2 Signaling and Inhibits Rho-Mediated Responses Induced by Lysophosphatidic Acid in Astroglial Cells. [PDF]

Int J Mol Sci
Olianas MC, Dedoni S, Onali P.
europepmc   +1 more source

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure-activity relationship of cloned LPA receptors

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure-activity relationship of cloned LPA receptors
We examined the structure-activity relationship of cloned lysophosphatidic acid (LPA) receptors (endothelial cell differentiation gene (EDG) 2, EDG4, and EDG7) by measuring [Ca2+](i) in Sf9 insect cells expressing each receptor using LPA with various acyl chains bound at either the sn-1 or the sn-2 position of the glycerol backbone.
openaire  

Gintonin as a Lysophosphatidic Acid-Enriched GPCR Ligand System: Molecular Architecture and Receptor Pharmacology in <i>Panax ginseng</i>. [PDF]

Biomolecules
Kim KH, Yoo BC.
europepmc   +1 more source

Lysophosphatidic acid mediates skeletal muscle fibrosis in denervation via activation of YAP/TAZ. [PDF]

JCI Insight
Cruz-Soca M, Córdova-Casanova A, Faundez-Contreras J, Martínez NW, Vaccaro-Rivera F, Bazaes-Astorga S, Gutiérrez-Rojas C, Gallardo FS, Rebolledo DL, Court FA, Chun J, Vio CP, Matus S, Casar JC, Brandan E.   +14 more
europepmc   +1 more source

Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: Possible role of LPA-binding proteins in activation of LPA receptors

Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: Possible role of LPA-binding proteins in activation of LPA receptors
Lysophosphatidic acid (LPA) exerts multiple biological functions through G protein-coupled receptors (EDG2/LPA1, EDG4/LPA2, and EDG7/LPA3) and is present in serum where it is associated with albumin. In this study we examined LPA activity in various biological fluids by measuring the LPA-induced increase in the intracellular concentration of calcium ...
openaire