Results 121 to 130 of about 271,314 (298)

Luciferase Assay v1

, 2019
Genetic reporter systems are widely used to study eukaryotic gene expression and cellular physiology. Applications include the study of receptor activity, transcription factors, intracellular signaling, mRNA processing and protein folding. Dual reporters are commonly used to improve experimental accuracy.
openaire   +1 more source

Covalent structure of subunits of bacterial luciferase: NH2-terminal sequence demonstrates subunit homology. [PDF]

, 1979
Thomas Baldwin, Mathias Ziegler, David Powers   +2 more
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Author Correction: GL261 luciferase-expressing cells elicit an anti-tumor immune response: an evaluation of murine glioma models [PDF]

, 2022
Victoria Sánchez, John Lynes, Stuart Walbridge, Xiang Wang, Nancy A. Edwards, Anthony Nwankwo, Hannah Sur, Gifty Dominah, Arnold Obungu, Nicholas Adamstein, Pradeep K. Dagur, Dragan Maric, Jeeva Munasinghe, John D. Heiss, Edjah K. Nduom   +14 more
openalex   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Gaussia princeps Luciferase as a Reporter for Transcriptional Activity, Protein Secretion, and Protein-Protein Interactions in Salmonella enterica Serovar Typhimurium

, 2011
Thorsten Wille, Kathrin Blank, Christiane Schmidt, Vivien Vogt, Roman G. Gerlach   +4 more
openalex   +2 more sources

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Monitoring of prostate cancer growth and metastasis using a PSA luciferase report plasmid in a mouse model

, 2014
Qiqi Mao, Yiwei Lin, Hong Chen, Kai Yang, Debo Kong, Hai Jiang   +5 more
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4T1-GFP-luciferase 24-hr lung colonization flow cytometry

, 2020
Eileen Shiuan
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Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

Advanced Science, EarlyView.
This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li, Huizhi Sun, Jing Liu, Yan Wu, Lin Wei, Jianming Li, Yudong Yuan, Peng Xie, Chao Xu, Guolu Luo, Yuqi Guan, Yukuan Feng, Antao Chang, Jihui Hao, Chongbiao Huang   +14 more
wiley   +1 more source

A Panel of Trypanosoma brucei Strains Tagged with Blue and Red-Shifted Luciferases for Bioluminescent Imaging in Murine Infection Models

, 2014
Nick Van Reet, Hélène Van de Vyver, Patient Pati Pyana, Annemie Van der Linden, Philippe Büscher   +4 more
openalex   +2 more sources