Results 101 to 110 of about 19,699 (283)
Genetically Modified Coelenterazine-Dependent Luciferases as Reporters for In Vitro Assay [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2017 Among the most important tasks of modern biotechnology is the development of new analytical techniques suitable for highly sensitive and specific detection of diagnostically important targets rapidly expanding their range with the progress in biomedical ...
Ludmila A. Frank +3 more
doaj
Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms [PDF]
, 2006 Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. Three of them, Asp, Glu, and (oxidized) Cys, function through their conjugation to Arg, one of destabilizing N-terminal residues that are recognized directly by
Brower, Christopher S. +7 more
core +2 more sources
Advanced Materials, EarlyView.Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin +14 more
wiley +1 more source
A SUCLA2 mutációk szerepe a mitokondrium foszforilációs rendszerének betegségeiben = The Role of SUCLA2 Mutations in the Disorders of the Mitochondrial Phosphorylation System [PDF]
, 2011 Ami a SUCLA2 knock-out egerek használatát illeti, az állatok létrehozása még mindig folyamatban van, annak ellenére, hogy a kifizetés teljes egészében megtörtént. Amint megérkeznek az állatok, munkacsoportunk elsődleges feladata a tervben szereplő, eddig
Chinopoulos, Christos +3 more
core
Advanced Materials, EarlyView.A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton +17 more
wiley +1 more source
Luciferase-Specific Coelenterazine Analogues for Optical Contamination-Free Bioassays
Scientific Reports, 2017 Spectral overlaps among the multiple optical readouts commonly cause optical contamination in fluorescence and bioluminescence. To tackle this issue, we created five-different lineages of coelenterazine (CTZ) analogues designed to selectively illuminate ...
Ryo Nishihara +5 more
doaj +1 more source
β‐Deuterium Isotope Effects on Firefly Luciferase Bioluminescence [PDF]
, 2017 Michael C. Pirrung +3 more
openalex +1 more source
Autoregulation of the Glial Gene Reversed Polarity in Drosophila Melanogaster [PDF]
, 2017 Autoregulation is the process where an encoded protein is able to bind to and positively or negatively regulate its own expression. Autoregulatory loops are crucial for sustained gene expression, and such loops have been demonstrated to be important for ...
Suiter, Chase
core +1 more source
Advanced Materials, EarlyView.Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole [PDF]
, 2016 2-Cyanobenzothiazoles (CBTs) are useful building blocks for: 1) luciferin derivatives for bioluminescent imaging; and 2) handles for bioorthogonal ligations.
Bayana, ME +5 more
core +2 more sources