Results 11 to 20 of about 8,005 (293)

Integration of AI-2 Based Cell-Cell Signaling with Metabolic Cues in Escherichia coli. [PDF]

open access: yesPLoS ONE, 2016
The quorum sensing molecule Autoinducer-2 (AI-2) is generated as a byproduct of activated methyl cycle by the action of LuxS in Escherichia coli. AI-2 is synthesized, released and later internalized in a cell-density dependent manner. Here, by mutational
Arindam Mitra   +4 more
doaj   +18 more sources

Overexpression of luxS Promotes Stress Resistance and Biofilm Formation of Lactobacillus paraplantarum L-ZS9 by Regulating the Expression of Multiple Genes

open access: yesFrontiers in Microbiology, 2018
Probiotics have evoked great interest in the past years for their beneficial effects. The aim of this study was to investigate whether luxS overexpression promotes the stress resistance of Lactobacillus paraplantarum L-ZS9.
Ruiyun Wu, Pinglan Li
exaly   +3 more sources

Characterization of AI-2/LuxS quorum sensing system in antibiotic resistance, pathogenicity of non carbapenemase-producing carbapenem-resistant Escherichia coli [PDF]

open access: yesBMC Microbiology
Background As a quorum sensing system, LuxS/AI-2 is closely associated with bacterial growth, biofilm formation, and virulence. As yet, it is not known how the luxS is associated with a diverse array of physiological activities in non- carbapenemase ...
Xiaohong Xu   +5 more
doaj   +2 more sources

Quorum Sensing via Autoinducer‐2 Promotes Colonisation and Host Adaptation in B. bifidum PRL2010 [PDF]

open access: yesMicrobial Biotechnology
Autoinducer‐2 (AI‐2) is a key signalling molecule that in many bacteria facilitates interspecies communication by regulating gene expression in response to population density through a process known as quorum sensing.
Francesca Turroni   +11 more
doaj   +2 more sources

CRISPR Interference (CRISPRi) Inhibition of luxS Gene Expression in E. coli: An Approach to Inhibit Biofilm

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Biofilm is a sessile bacterial accretion embedded in self-producing matrix. It is the root cause of about 80% microbial infections in human. Among them, E. coli biofilms are most prevalent in medical devices associated nosocomial infections.
Asad U Khan
exaly   +3 more sources

In-Silico Prediction and Modeling of the Quorum Sensing LuxS Protein and Inhibition of AI-2 Biosynthesis in Aeromonas hydrophila

open access: yesMolecules, 2018
luxS is conserved in several bacterial species, including A. hydrophila, which causes infections in prawn, fish, and shrimp, and is consequently a great risk to the aquaculture industry and public health. luxS plays a critical role in the biosynthesis of
Zujie Yao, Wanxin Li, Wenxiong Lin
exaly   +3 more sources

Unveiling the Hidden Mechanism: How LuxS/AI-2 quorum sensing system drives antimicrobial resistance in Salmonella pullorum through activation of the efflux pump AcrAB-TolC [PDF]

open access: yesPoultry Science
Understanding the antimicrobial resistance (AMR) mechanism of Salmonella pullorum (SP), which is widespread among yellow chickens in China, is crucial for reducing significant economic losses in the industry.
Ziheng Xu   +6 more
doaj   +2 more sources

Helicobacter pylori luxS mutants cause hyperinflammatory responses during chronic infection [PDF]

open access: yesMicrobiology Spectrum
Helicobacter pylori infects roughly half the world’s population, causing gastritis, peptic ulcers, and gastric cancer in a subset. These pathologies occur in response to a chronic inflammatory state, but it is not fully understood how H.
Christina Yang   +6 more
doaj   +2 more sources

Dissecting of the AI-2/LuxS Mediated Growth Characteristics and Bacteriostatic Ability of Lactiplantibacillus plantarum SS-128 by Integration of Transcriptomics and Metabolomics

open access: yesFoods, 2022
Lactiplantibacillus plantarum could regulate certain physiological functions through the AI-2/LuxS-mediated quorum sensing (QS) system. To explore the regulation mechanism on the growth characteristics and bacteriostatic ability of L. plantarum SS-128, a
Yilin Qian   +5 more
doaj   +1 more source

Modulation of Campylobacter jejuni Motility, Adhesion to Polystyrene Surfaces, and Invasion of INT407 Cells by Quorum-Sensing Inhibition

open access: yesMicroorganisms, 2020
Campylobacter jejuni is a major foodborne pathogen, and the LuxS-mediated quorum-sensing (QS) system influences its motility, biofilm formation, invasion, host colonization, and virulence. QS therefore represents a target for the control of C.
Katarina Šimunović   +3 more
doaj   +1 more source

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