Clostridioides difficile LuxS mediates inter-bacterial interactions within biofilms [PDF]
Scientific Reports, 2019 The anaerobic gut pathogen, Clostridioides difficile, forms adherent biofilms that may play an important role in recurrent C. difficile infections. The mechanisms underlying C.
Ross T. Slater +4 more
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2D proteome analysis initiates new Insights on the
BMC Microbiology, 2009 Background Quorum sensing is a term describing a bacterial communication system mediated by the production and recognition of small signaling molecules. The LuxS enzyme, catalyzing the synthesis of AI-2, is conserved in a wide diversity of bacteria. AI-2
Vanderleyden Jos +5 more
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Bifidobacteria exhibit LuxS-dependent autoinducer 2 activity and biofilm formation. [PDF]
PLoS ONE, 2014 Autoinducer-2 (AI-2) molecules are one class of signalling molecules involved in gene regulation dependent on population density in a mechanism commonly referred to as quorum sensing (QS).
Zhongke Sun +4 more
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Transcriptional and post-transcriptional regulation of the Escherichia coli luxS mRNA; involvement of the sRNA MicA. [PDF]
PLoS ONE, 2010 BackgroundThe small RNA (sRNA) MicA has been shown to post-transcriptionally regulate translation of the outer membrane protein A (OmpA) in Escherichia coli.
Klas I Udekwu
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Uncovering the link between the SpnIII restriction modification system and LuxS in Streptococcus pneumoniae meningitis isolates [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 Streptococcus pneumoniae is capable of randomly switching their genomic DNA methylation pattern between six distinct bacterial subpopulations (A-F) via recombination of a type 1 restriction-modification locus, spnIII.
Hannah N. Agnew +10 more
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The Impairment of Methyl Metabolism From luxS Mutation of Streptococcus mutans [PDF]
Frontiers in Microbiology, 2018 The luxS gene is present in a wide range of bacteria and is involved in many cellular processes. LuxS mutation can cause autoinducer(AI)-2 deficiency and methyl metabolism disorder. The objective of this study was to demonstrate that, in addition to AI-2-
Xuchen Hu +8 more
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LuxS-independent formation of AI-2 from ribulose-5-phosphate [PDF]
BMC Microbiology, 2008 Background In many bacteria, the signal molecule AI-2 is generated from its precursor S-ribosyl-L-homocysteine in a reaction catalysed by the enzyme LuxS.
Hardie Kim R +3 more
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The
BMC Research Notes, 2011 Background The luxS gene in Shewanella oneidensis was shown to encode an autoinducer-2 (AI-2)-like molecule, the postulated universal bacterial signal, but the impaired biofilm growth of a luxS deficient mutant could not be restored by AI-2, indicating ...
Wagner-Döbler Irene +3 more
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Helicobacter pylori luxS mutants cause hyperinflammatory responses during chronic infection [PDF]
Microbiology SpectrumHelicobacter pylori infects roughly half the world’s population, causing gastritis, peptic ulcers, and gastric cancer in a subset. These pathologies occur in response to a chronic inflammatory state, but it is not fully understood how H.
Christina Yang +6 more
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Quorum sensing LuxS/autoinducer-2 inhibits Enterococcus faecalis biofilm formation ability [PDF]
Journal of Applied Oral Science, 2018 Objective: To investigate the relation between biofilm formation ability and quorum sensing gene LuxS/AI-2. Materials and Methods: Enterococcus faecalis (E. faecalis) standard strain ATCC 29212 was used in the study.
Yue Yang +3 more
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