Results 91 to 100 of about 27,751 (253)

Predictive Factors for Failed Sentinel Lymph Node Mapping in Endometrial Cancer: A Retrospective Multicenter Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives This study aims to evaluate the predictive factors associated with failed sentinel lymph node (SLN) mapping in a large, retrospective cohort of patients with early‐stage endometrial cancer (EC). Methods We retrospectively evaluated a series of EC patients who underwent laparoscopic SLN mapping with intracervical ...
Cristina Taliento, Gennaro Scutiero, Giuseppe Cucinella, Vito Chiantera, Giovanni Pontrelli, Marko Klaric, Dragan Belci, Martin Steinkasserer, Stefano Restaino, Ruby Martinello, Orsola Brasile, Martina Arcieri, Sara Pregnolato, Giulia Pellecchia, Giulia Soraci, Rosa Taratufolo, Carmelia Milano, Marcello Desgro, Francesca Davià, Mariano Catello Di Donna, Dino Becic, Sara Notaro, Giuseppe Vizzielli, Pantaleo Greco   +23 more
wiley   +1 more source

EphrinB2-mediated CDK5/ISL1 pathway enhances cardiac lymphangiogenesis and alleviates ischemic injury by resolving post-MI inflammation

Signal Transduction and Targeted Therapy
EphrinB2 (erythropoietin-producing hepatoma interactor B2) is a key Eph/ephrin family member, promoting angiogenesis, vasculogenesis, and lymphangiogenesis during embryonic development. However, the role of EphrinB2 in cardiac lymphangiogenesis following
Yingnan Bai, Liming Chen, Fanghao Guo, Jinghong Zhang, Jinlin Hu, Xuefei Tao, Qing Lu, Wenyi Li, Xueying Chen, Ting Gong, Nan Qiu, Yawei Jin, Lifan Yang, Yu Lei, Chengchao Ruan, Qing Jing, John P. Cooke, Shijun Wang, Yunzeng Zou, Junbo Ge   +19 more
doaj   +1 more source

1275‐nm Photobiomodulation Alleviates Brain Drainage Impairment as a Promising Therapeutic Strategy for Aging‐Related Neurological Decline

Aging Cell, EarlyView.
Noninvasive 1275‐nm photobiomodulation improves brain drainage and promotes lymphatic clearance of advanced glycation end products (AGEs) in an aging model (AM) in male mice. These effects are associated with nitric oxide release‐mediated dilation of meningeal lymphatic vessels (MLVs).
Hao Lin, Shaojun Liu, Qihang Yang, Junming Li, Jue Wang, Oxana Semyachkina‐Glushkovskaya, Dongyu Li, Tingting Yu, Dan Zhu   +8 more
wiley   +1 more source

High Mobility Group Box-1 Promotes Inflammation-Induced Lymphangiogenesis via Toll-Like Receptor 4-Dependent Signalling Pathway. [PDF]

PLoS ONE, 2016
Lymphangiogenesis in inflammation has received considerable attention in recent years. Administration of modulating lymphangiogenesis provides more possibilities of treating inflammation-associated diseases.
Longhui Han, Minglian Zhang, Mengmeng Wang, Jinchen Jia, Miying Zhao, Yiming Fan, Xiaorong Li   +6 more
doaj   +1 more source

Mast Cells, Angiogenesis and Lymphangiogenesis in Human Gastric Cancer

International Journal of Molecular Sciences, 2019
Gastric cancer is diagnosed in nearly one million new patients each year and it remains the second leading cause of cancer-related deaths worldwide. Although gastric cancer represents a heterogeneous group of diseases, chronic inflammation has been shown
G. Sammarco, G. Varricchi, V. Ferraro, M. Ammendola, M. De Fazio, D. Altomare, Maria Luposella, L. Maltese, G. Currò, G. Marone, G. Ranieri, R. Memeo   +11 more
semanticscholar   +1 more source

Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis

Nature Communications, 2020
Proteolytical processing of the growth factor VEGFC through the concerted activity of CCBE1 and ADAMTS3 is required for lymphatic development to occur.
Guangxia Wang, L. Muhl, Y. Padberg, Laura Dupont, J. Peterson-Maduro, M. Stehling, F. le Noble, A. Colige, C. Betsholtz, S. Schulte-Merker, Andreas van Impel   +10 more
semanticscholar   +1 more source

Microbial and Metabolic Disorders in Cervical Cancer: Structural Insights, Biomarkers, Mechanisms, and Therapeutic Strategies

Cancer Science, EarlyView.
We unravel synergistic mechanisms by which microbial‐host metabolic networks regulate the tumor immune microenvironment and therapy resistance, bridging gaps between microbiota research and cancer metabolism. Identified biomarkers (e.g., Lactobacillus, C8‐ceramide‐1‐phosphate) and therapeutic approaches (e.g., FMT combined with immune checkpoint ...
Hong Tao, Luyu Wang, Yi Ding, Lixian Yi, Mutian Han, Mengmeng Gu, Jian Wu   +6 more
wiley   +1 more source

Adenosine A2a receptor promotes lymphangiogenesis and lymph node metastasis

OncoImmunology, 2019
The formation of new lymphatic vessels, or lymphangiogenesis, is a critical step of the tissue repair program. In pathological conditions involving chronic inflammation or tumorigenesis, this process is often dysregulated and can contribute to disease ...
Bertrand Allard, Isabelle Cousineau, David Allard, Laurence Buisseret, Sandra Pommey, Pavel Chrobak, John Stagg   +6 more
doaj   +1 more source

Diagnosis and surgical management of septic peritonitis in small animals: A review

Veterinary Surgery, EarlyView.
Abstract Background Septic peritonitis (SP) is a complex disease with significant morbidity and mortality. Diagnosis can be challenging, and lack of a timely diagnosis may impact survival. Aim The aim of this review was to synthesize current knowledge on the diagnosis and surgical management of SP in dogs and cats.
Bonnie G. Campbell, Shana K. O'Marra
wiley   +1 more source

Lymphangiogenesis in kidney and lymph node mediates renal inflammation and fibrosis

Science Advances, 2019
Expanded lymphatic vessels (LVs) in kidneys and renal draining lymph nodes (RDLNs) promote intrarenal inflammation and fibrosis. Lymphangiogenesis is associated with chronic kidney disease (CKD) and occurs following kidney transplant.
Guangchang Pei, Ying Yao, Qian Yang, Meng Wang, Yuxi Wang, Jianliang Wu, Pengge Wang, Yueqiang Li, F. Zhu, Juan Yang, Ying Zhang, Weiqi Yang, Xuan Deng, Zhi Zhao, Han Zhu, S. Ge, Min Han, R. Zeng, Gang Xu   +18 more
semanticscholar   +1 more source