Results 91 to 100 of about 36,476 (247)

Efferocytosis in Health and Disease

MedComm, Volume 6, Issue 12, December 2025.
Efferocytosis in health and disease. Efferocytosis integrates apoptotic cell recognition, engulfment, digestion, and reprogramming to link cell clearance with tissue repair. Molecular checkpoints balance “eat‐me” signals such as phosphatidylserine against inhibitory “don't‐eat‐me” cues like CD47, while TAM receptors, scavenger receptors, and integrins ...
Chaofu Li, Yukun Yang, Fating Zhou, Qiuyan Jiang, Yingying Jiang, Xuanjie Huang, Yiqiong Zhang, Zhengmeng Ye, Gang Xu, Guoying Kao, Ke Zhou, Fan Yang, Jun Xiao, Wei Wu, Chuanwei Li   +14 more
wiley   +1 more source

Celecoxib in breast cancer prevention and therapy. [PDF]

, 2018
Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation, development, and aggressiveness of many malignancies. The use of celecoxib, a novel NSAID, is repetitively
Cao, Wei, Hao, Qiongyu, Li, Jieqing, Vadgama, Jaydutt V, Wu, Yong   +4 more
core  

Lymphatic expression of CLEVER-1 in breast cancer and its relationship with lymph node metastasis [PDF]

, 2011
BACKGROUND Mechanisms regulating breast cancer lymph node metastasis are unclear. Staining of CLEVER-1 (common lymphatic endothelial and vascular endothelial receptor-1) in human breast tumors was used, along with in vitro techniques, to assess ...
Ammar, Aula, Ellis, Ian O., Martin, Stewart G., Mohammed, Rabab A.A., Paish, Emma C., Pepper, Michael, Salmi, Marko   +6 more
core   +3 more sources

Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer [PDF]

, 2020
Shaoquan Zheng, Lu Yang, Yutian Zou, Jie‐Ying Liang, Peng Liu, Guanfeng Gao, Anli Yang, Hailin Tang, Xiaoming Xie   +8 more
openalex   +1 more source

A Rare Cause of Massive Scrotal Elephantiasis: Case Report and Literature Review

Trends in Urology &Men's Health, Volume 16, Issue 6, December 2025.
ABSTRACT Scrotal lymphedema is a rare late complication of testicular cancer treatment, with most reported cases occurring in the early postoperative period. Massive scrotal elephantiasis manifesting more than a decade after postchemotherapy retroperitoneal lymph node dissection (pc‐RPLND) has not previously been described.
David Toro Tole, Jonathon Bowden, Bilal Mir, Joe Hedger, Sheshang Kamath   +4 more
wiley   +1 more source

The immune regulatory role of lymphangiogenesis in kidney disease

Journal of Translational Medicine
The renal lymphatic system is critical for maintaining kidney homeostasis and regulating the immune response inside the kidney. In various kidney pathological situations, the renal lymphatic network experiences lymphangiogenesis, which is defined as the ...
Xiangheng Lu, Kuai Ma, Junyi Ren, Haoyu Peng, Jia Wang, Xiaoxiao Wang, Moussa Ide Nasser, Chi Liu   +7 more
doaj   +1 more source

Novel mutation in CCBE 1 as a cause of recurrent hydrops fetalis from Hennekam lymphangiectasia-lymphedema syndrome-1. [PDF]

, 2018
Whole exome sequencing (WES) was used to determine the etiology of recurrent hydrops fetalis in this case of Hennekam lymphangiectasia-lymphedema syndrome-1.
Andreasen, Tara S, Lamale-Smith, Leah M, Mao, Rong, Melber, Dora J, Miller, Christine E, Moore, Thomas R, Tvrdik, Tatiana, Woelkers, Douglas A   +7 more
core  

1275‐nm Photobiomodulation Alleviates Brain Drainage Impairment as a Promising Therapeutic Strategy for Aging‐Related Neurological Decline

Aging Cell, Volume 24, Issue 12, December 2025.
Noninvasive 1275‐nm photobiomodulation improves brain drainage and promotes lymphatic clearance of advanced glycation end products (AGEs) in an aging model (AM) in male mice. These effects are associated with nitric oxide release‐mediated dilation of meningeal lymphatic vessels (MLVs).
Hao Lin, Shaojun Liu, Qihang Yang, Junming Li, Jue Wang, Oxana Semyachkina‐Glushkovskaya, Dongyu Li, Tingting Yu, Dan Zhu   +8 more
wiley   +1 more source

Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway [PDF]

, 2014
Background: Signaling through vascular endothelial growth factor C (VEGF–C) and VEGF receptor 3 (VEGFR-3) plays a central role in lymphangiogenesis and the metastasis of several cancers via the lymphatics.
Groopman, Jerome E, Jiang, Shuxian, Kuzontkoski, Paula M, Li, Dean Y, Yu, Jinlong, Zhang, Xuefeng, Zhu, Weiquan   +6 more
core   +2 more sources

Microbial and Metabolic Disorders in Cervical Cancer: Structural Insights, Biomarkers, Mechanisms, and Therapeutic Strategies

Cancer Science, Volume 116, Issue 12, Page 3228-3238, December 2025.
We unravel synergistic mechanisms by which microbial‐host metabolic networks regulate the tumor immune microenvironment and therapy resistance, bridging gaps between microbiota research and cancer metabolism. Identified biomarkers (e.g., Lactobacillus, C8‐ceramide‐1‐phosphate) and therapeutic approaches (e.g., FMT combined with immune checkpoint ...
Hong Tao, Luyu Wang, Yi Ding, Lixian Yi, Mutian Han, Mengmeng Gu, Jian Wu   +6 more
wiley   +1 more source