Lymphatics at the crossroads of angiogenesis and lymphangiogenesis
Journal of Anatomy, 2004 AbstractThe lymphatic system is implicated in interstitial fluid balance regulation, immune cell trafficking, oedema and cancer metastasis. However, the sequence of events that initiate and coordinate lymphatic vessel development (lymphangiogenesis) remains obscure.
SCAVELLI, C. +6 more
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Apelin promotes lymphangiogenesis and lymph node metastasis [PDF]
, 2015 Whereas the role of the G-protein-coupled APJ receptor and its ligand, apelin, in angiogenesis has been well documented, the ability of the apelin/APJ system to induce lymphangiogenesis and lymphatic metastasis has been largely unexplored.
Berger W +15 more
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Global weak solutions to a fractional Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]
arXivA spectral-fractional Cahn-Hilliard cross-diffusion system, which describes the pre-patterning of lymphatic vessel morphology in collagen gels, is studied. The model consists of two higher-order quasilinear parabolic equations and describes the evolution of the fiber phase volume fraction and the solute concentration.
arxiv
The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects [PDF]
, 2017 Este es el manuscrito que fue aceptado y que finalmente se publicó en Cancer Letters con el DOI: 10.1016/j.canlet.2016.10.037The natural bioactive compound damnacanthal inhibits several tyrosine kinases.
García-Vilas, Javier A. +4 more
core
Lymphangiogenesis and its role in cancer.
Histology and histopathology, 2005 In many tumour types, lymphatic vasculature serves as a major route for tumour metastasis. The dissemination of malignant cells to the regional lymph nodes is an early step in the progression of many solid tumours and is an important determinant of prognosis.
Al-Rawi, M.A.A. +2 more
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Existence of global weak solutions to a Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]
arXivThe global-in-time existence of weak solutions to a degenerate Cahn-Hilliard cross-diffusion system with singular potential in a bounded domain with no-flux boundary conditions is proved. The model consists of two coupled parabolic fourth-order partial differential equations and describes the evolution of the fiber phase volume fraction and the solute ...
arxiv
Error Analysis of a Fully Discrete Scheme for The Cahn--Hilliard Cross-Diffusion Model in Lymphangiogenesis [PDF]
arXivThis paper introduces a stabilized finite element scheme for the Cahn--Hilliard cross-diffusion model, which is characterized by strongly coupled mobilities, nonlinear diffusion, and complex cross-diffusion terms. These features pose significant analytical and computational challenges, particularly due to the destabilizing effects of cross-diffusion ...
arxiv
Role of Lymphatic Vessels in Tumor Immunity: Passive Conduits or Active Participants? [PDF]
, 2018 Research in lymphatic biology and cancer immunology may soon intersect as emerging evidence implicates the lymphatics in the progression of chronic inflammation and autoimmunity as well as in tumor metastasis and immune escape. Like the blood vasculature,
Lund, Amanda, Swartz, Melody
core
VEGF-C/VEGFR-3 and PDGF-B/PDGFR-b pathways in embryonic lymphangiogenesis [PDF]
, 2008 The circulatory system comprises the blood vascular system and the lymphatic vascular system. These two systems function in parallel. Blood vessels form a closed system that delivers oxygen and nutrients to the tissues and removes waste products from the
Haiko, Paula
core
Cardiac lymphatic vessels, transport, and healing of the infarcted heart [PDF]
, 2017 Huang, Li-Hao +2 more
core +2 more sources