Results 41 to 50 of about 43,762 (300)

Lymphangiogenesis is required for pancreatic islet inflammation and diabetes. [PDF]

open access: yesPLoS ONE, 2011
Lymphangiogenesis is a common phenomenon observed during inflammation and engraftment of transplants, but its precise role in the immune response and underlying mechanisms of regulation remain poorly defined. Here we showed that in response to injury and
Na Yin   +6 more
doaj   +1 more source

The intestinal lymphatic system: Functions and metabolic implications [PDF]

open access: yes, 2019
The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Cifarelli, Vincenza, Eichmann, Anne
core   +2 more sources

M2b macrophages stimulate lymphangiogenesis to reduce myocardial fibrosis after myocardial ischaemia/reperfusion injury

open access: yesPharmaceutical Biology, 2022
Context Therapeutic lymphangiogenesis is a new treatment for cardiovascular diseases. Our previous study showed M2b macrophages can alleviate myocardial ischaemia/reperfusion injury (MI/RI).
Cuiping Wang   +7 more
semanticscholar   +1 more source

circNFIB1 inhibits lymphangiogenesis and lymphatic metastasis via the miR-486-5p/PIK3R1/VEGF-C axis in pancreatic cancer

open access: yesMolecular Cancer, 2020
Background Patients with lymph node (LN)-positive pancreatic ductal adenocarcinoma (PDAC) have extremely poor survival rates. Circular RNAs (circRNAs), a newly discovered type of endogenous noncoding RNAs, have been proposed to mediate the progression of
Yao Kong   +9 more
semanticscholar   +1 more source

CD137L-macrophage induce lymphatic endothelial cells autophagy to promote lymphangiogenesis in renal fibrosis

open access: yesInternational Journal on Biological Sciences, 2022
Renal lymphangiogenesis is a new field of international nephrology in recent years and plays an important role in the progression of chronic renal disease.
Haotian Wei   +8 more
semanticscholar   +1 more source

Lymphangiogenesis and tumor metastasis [PDF]

open access: yesThrombosis and Haemostasis, 2003
SummaryIn several human cancers, increased expression in primary tumors of vascular endothelial growth factor-C (VEGF-C) is correlated with regional lymph node metastasis. Studies using transgenic mice overexpressing VEGF-C, or xenotransplantation of VEGF-C-expressing tumor cells into immunodeficient mice, have demonstrated a role for VEGF-C in tumor ...
Riccardo E, Nisato   +2 more
openaire   +5 more sources

Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis

open access: yesCell Reports, 2019
Summary: Lymphatic vascular development establishes embryonic and adult tissue fluid balance and is integral in disease. In diverse vertebrate organs, lymphatic vessels display organotypic function and develop in anĀ organ-specific manner. In all settings,
Adam J. Vogrin   +9 more
doaj   +1 more source

Myeloid Cells and Lymphangiogenesis [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2012
The lymphatic vascular system and the hematopoietic system are intimately connected in ontogeny and in physiology. During embryonic development, mammalian species derive a first lymphatic vascular plexus from the previously formed anterior cardinal vein, whereas birds and amphibians have a lymphatic vascular system of dual origin, composed of lymphatic
Zumsteg, Adrian, Christofori, Gerhard
openaire   +3 more sources

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

open access: yes, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker   +16 more
core   +2 more sources

Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas

open access: yesScience Advances, 2021
New approach for immune cell recruitment in therapeutic anticancer vaccines drives antigenically broad and long-lasting immunity. In melanoma, the induction of lymphatic growth (lymphangiogenesis) has long been correlated with metastasis and poor ...
M. Sasso   +7 more
semanticscholar   +1 more source

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