Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]
Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Ahn MJ+48 more
core +1 more source
Lymphedema and Therapeutic Lymphangiogenesis
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities. Lymphedema is divided into primary and secondary forms based on the underlying etiology. Despite substantial advances in both surgical and conservative techniques, therapeutic options for the management of lymphedema are
Yukihiro Saito+3 more
openaire +3 more sources
Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker+16 more
core +2 more sources
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection.
Mehul Patnam+7 more
doaj +1 more source
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
AE Koch+33 more
core +2 more sources
Lung cancer ranks the first cancer-related morbidity and mortality in China. Tumor metastasis always predicts the poor prognosis for patients. Moreover, lymphatic metastasis is one of the most significant predictors of poor prognosis in patients with non-
Xiayao DIAO, Chao GUO, Shanqing LI
doaj +1 more source
Structure-preserving semi-convex-splitting numerical scheme for a Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]
A fully discrete semi-convex-splitting finite-element scheme with stabilization for a Cahn-Hilliard cross-diffusion system is analyzed. The system consists of parabolic fourth-order equations for the volume fraction of the fiber phase and solute concentration, modeling pre-patterning of lymphatic vessel morphology.
arxiv
Lymphatic expression of CLEVER-1 in breast cancer and its relationship with lymph node metastasis [PDF]
BACKGROUND Mechanisms regulating breast cancer lymph node metastasis are unclear. Staining of CLEVER-1 (common lymphatic endothelial and vascular endothelial receptor-1) in human breast tumors was used, along with in vitro techniques, to assess ...
Ammar, Aula+6 more
core +3 more sources
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development [PDF]
The C-type lectin receptor CLEC-2 signals through a pathway that is critically dependent on the tyrosine kinase Syk. We show that homozygous loss of either protein results in defects in brain vascular and lymphatic development, lung inflation and ...
Abramoff+66 more
core +2 more sources
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice [PDF]
Reverse cholesterol transport (RCT) refers to the mobilization of cholesterol on HDL particles (HDL-C) from extravascular tissues to plasma, ultimately for fecal excretion. Little is known about how HDL-C leaves peripheral tissues to reach plasma.
Alan R. Tall+20 more
core +8 more sources