Results 61 to 70 of about 36,476 (247)

Transient Ingrowth of Lymphatic Vessels into the Physiologically Avascular Cornea Regulates Corneal Edema and Transparency

Scientific Reports, 2017
Lymphangiogenesis is essential for fluid homeostasis in vascularized tissues. In the normally avascular cornea, however, pathological lymphangiogenesis mediates diseases like corneal transplant rejection, dry eye disease, and allergy.
Deniz Hos, Anne Bukowiecki, Jens Horstmann, Felix Bock, Franziska Bucher, Ludwig M. Heindl, Sebastian Siebelmann, Philipp Steven, Reza Dana, Sabine A. Eming, Claus Cursiefen   +10 more
doaj   +1 more source

A Review of Mathematical Models for the Formation of\ud Vascular Networks [PDF]

, 2012
Mainly two mechanisms are involved in the formation of blood vasculature: vasculogenesis and angiogenesis. The former consists of the formation of a capillary-like network from either a dispersed or a monolayered population of endothelial cells ...
Bell, C. G., Preziosi, L., Scianna, M.
core  

Targeted Medical Therapies for Vascular Anomalies: A Clinical Review

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Vascular anomalies represent a broad spectrum of disorders characterized by aberrant blood or lymphatic vessel development, which can lead to complex clinical phenotypes. Historically, vascular anomalies were classified solely on the basis of their clinical and histopathologic features.
Whitney Eng
wiley   +1 more source

VEGFR-3 signaling regulates triglyceride retention and absorption in the intestine [PDF]

, 2018
The lymphatic system transports dietary lipids absorbed and packaged as chylomicrons by enterocytes, for delivery to the bloodstream. Once considered a passive drainage, chylomicron entry into intestinal lymphatic vessels, or lacteals, is now emerging to
Cifarelli, Vincenza, Shew, Trevor, Wolins, Nathan E   +2 more
core   +2 more sources

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva, Carla Roberta Peachazepi Moraes, Bruno Kosa Lino Duarte, Gislaine Borba Oliveira, Herton Luiz Alves Sales Filho, Paula de Melo Campos, Sara Teresinha Olalla Saad, Erich Vinicius De Paula   +7 more
wiley   +1 more source

RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription [PDF]

, 2013
Mechanisms governing the distinct temporal dynamics that characterize post-natal angiogenesis and lymphangiogenesis elicited by cutaneous wounds and inflammation remain unclear.
Adini, Irit, Bagchi, Mandrita, Benjamin, Laura E., Blachon, Stephanie, Gerald, Damien, Hopkins, Benjamin, Kazerounian, Shiva, Khedkar, Santosh, Klagsbrun, Michael, Kurschat, Peter, Nagy, Janice A., Perruzzi, Carole, Prendergast, George C., Rigby, Alan C., Shechter, Sharon, Sherris, David, Stuhlmann, Heidi, Varnau, Joseph   +17 more
core   +2 more sources

Lymph Node‐Targeted Nanomaterials for Controlled Nano‐Immunotherapy

Small Structures, EarlyView.
This study primarily investigates lymph node‐targeted immunotherapeutic strategies, focusing on the mechanisms of immune response regulation within lymph nodes. By targeting distinct immune signaling pathways, we systematically explore the development of nanodrug delivery systems specifically designed for lymph node targeting to achieve enhanced ...
Yitong Zhao, Mengjun Wang, Ming Ma, Yu Zhang, Haoan Wu   +4 more
wiley   +1 more source

CRIP1 Reshapes the Gastric Cancer Microenvironment to Facilitate Development of Lymphatic Metastasis

Advanced Science, 2023
Lymphangiogenesis in tumors provides an auxiliary route for cancer cell invasion to drainage lymph nodes, facilitating the development of lymphatic metastasis (LM).
Zhonghua Wu, Bicheng Qu, Minxian Yuan, Jingjing Liu, Cen Zhou, Mingwei Sun, Zhexu Guo, Yaqing Zhang, Yongxi Song, Zhenning Wang   +9 more
doaj   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Apelin promotes lymphangiogenesis and lymph node metastasis [PDF]

, 2014
International ...
Berger, Walter, Berta, Judit, Döme, Balázs, Garay, Tamás, Groger, Marion, Grusch, Michael, Hegedűs, Balázs, Hoda, Mir Alireza, Klepetko, Walter, Laszlo, Viktória, Masri, Bernard, Paku, Sándor, Rozsas, Anita, Rényi-Vámos, Ferenc, Torok, Szilvia, Tóvári, József   +15 more
core   +3 more sources