Results 61 to 70 of about 23,756 (251)

Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection

Infection and Immunity, 2021
Vascular remodeling is a phenomenon seen in the cutaneous lesions formed during infection with Leishmania parasites. Within the lesion, Leishmania major infection leads to the infiltration of inflammatory cells, including macrophages, and is associated ...
Anne Bowlin, Hayden Roys, Humphrey Wanjala, Manjunath Bettadapura, Gopinath Venugopal, Jessica Surma, M. Simon, Tiffany Weinkopff   +7 more
semanticscholar   +1 more source

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

Advanced Science, EarlyView.
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan, Chun‐Miao Deng, Lin Tang, Shu‐Jun Li, Tao‐Yang Xu, Xian Wei, Xin‐Yi Zhang, Can‐Can Zheng, Li Deng, Cui Shao, Zhong‐Min Ouyang, Alfred King‐Yin Lam, Rong Zhang, Jun Liu, Xing‐Yuan Shi, Zhen‐Yu Pan, Wei Dai, Ming‐Liang He, Simon Law, Xu Li, Xiao‐Bing Chen, Cheng Zhou, Bin Li, Wen‐Wen Xu   +23 more
wiley   +1 more source

Lymphangiogenesis and colorectal cancer

Saudi Medical Journal, 2017
Lymphatic metastasis is an important event in the progress of metastasis in colorectal cancer (CRC). The purpose of this article is to assess the role of lymphangiogenesis on CRC. In peritumoral areas of CRC, the lymphatic microvessel density (LMVD) is higher than those in normal colorectal tissues.
Yigang Chen, Ciyou Huang
openaire   +3 more sources

Focus on lymphangiogenesis in tumor metastasis [PDF]

Cancer Cell, 2005
M.G.A. and S.A.S. are supported by Senior Research Fellowships from the National Health and Medical Research Council of Australia (NHMRC) and the Pfizer Foundation, respectively, and by a Program Grant from the NHMRC. B.K.M. is a recipient of a Melbourne Research Scholarship from the University of Melbourne.
Steven A. Stacker, Bradley McColl, Marc G. Achen   +2 more
openaire   +3 more sources

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

Advanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai, Xuan Lu, Xu Yan, Han Su, Yuejun Lin, Zhaowei Jiang, Zhixian Zong, Haixing Wang, Leo Yik Chun Yan, Xiaoting Zhang, Ming Wang, Zhengmeng Yang, Jiakang Jin, Yaofeng Wang, Wayne Yuk‐Wai Lee, Xiaohua Jiang, Ho Ko, Lu Feng, Micky D. Tortorella, Sien Lin, Gang Li   +20 more
wiley   +1 more source

Angiogenesis and lymphangiogenesis in bronchial asthma [PDF]

Allergy, 2010
To cite this article: Detoraki A, Granata F, Staibano S, Rossi FW, Marone G, Genovese A. Angiogenesis and lymphangiogenesis in bronchial asthma. Allergy 2010; 65: 946–958.AbstractNeovascularization plays a prominent role in inflammation and tissue remodeling in several chronic inflammatory disorders.
Detoraki A., Granata F., STAIBANO, STEFANIA, ROSSI, FRANCESCA WANDA, MARONE, GIANNI, GENOVESE, ARTURO   +5 more
openaire   +4 more sources

Cow's milk protein allergy with protein‐losing enteropathy under the scope

JPGN Reports, EarlyView.
ABSTRACT Objectives Cow's milk protein allergy (CMPA) is very frequent in infants. Presentation is variable, and symptoms fluctuate in intensity. Diagnosis can be challenging as it is mostly clinical. In severe cases, patients can present with anasarca secondary to protein‐losing enteropathy (PLE).
Morgane Thorens‐Borgeat, Géraldine Blanchard‐Rohner, Salim Ramadan, Jean‐Christophe Caubet, Laetitia‐Marie Petit, Valerie McLin, Anne‐Laure Rougemont   +6 more
wiley   +1 more source

Targeting tubulointerstitial remodeling in proteinuric nephropathy in rats

Disease Models & Mechanisms, 2015
Proteinuria is an important cause of tubulointerstitial damage. Anti-proteinuric interventions are not always successful, and residual proteinuria often leads to renal failure.
Saleh Yazdani, Ryanne S. Hijmans, Fariba Poosti, Wendy Dam, Gerjan Navis, Harry van Goor, Jacob van den Born   +6 more
doaj   +1 more source

Extracellular vesicle-associated VEGF-C promotes lymphangiogenesis and immune cells infiltration in endometriosis

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Endometriosis is a highly prevalent proinflammatory disease without reliable diagnostic biomarkers and cannot be cured by nowadays’ medical treatments.
Wan-Ning Li, Kuei-Yang Hsiao, Chu-An Wang, Ning Chang, Pei-Ling Hsu, Chung-hsien Sun, Shang-Rung Wu, Meng-Hsing Wu, S. Tsai   +8 more
semanticscholar   +1 more source

Spatiotemporal Interrogation of Single Spheroids Using Multiplexed Nanoplasmonic‐Fluorescence Imaging

Small Methods, EarlyView.
This work introduces a multiplexed imaging platform that integrates nanoplasmonic sensing with fluorescence microscopy for concomitant monitoring of extraspheroid secretions and intraspheroid features over extended periods with spatiotemporal resolution.
Saeid Ansaryan, Yung‐Cheng Chiang, Yen‐Cheng Liu, Jiayi Tan, Luis Francisco Lorenzo‐Martín, Matthias P. Lutolf, Genrich Tolstonog, Hatice Altug   +7 more
wiley   +1 more source