Results 21 to 30 of about 4,142,040 (366)
Frontiers in Immunology, 2023 IntroductionHemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition, and its diagnosis may be challenging. In particular, some cases show close similarities to sepsis (fever, organ failure, and high ferritin), but their treatment, while ...
Sylvain Raimbault +7 more
doaj +1 more source
Increased lymphocyte activation and atherosclerosis in CD47-deficient mice
Scientific Reports, 2019 CD47, also known as integrin-associated protein (IAP), is a transmembrane protein with multiple biological functions including regulation of efferocytosis and leukocyte trafficking.
D. Engelbertsen +12 more
semanticscholar +1 more source
Biomedical Journal, 2022 T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
doaj
Activated T lymphocytes in uveitis. [PDF]
British Journal of Ophthalmology, 1988 Two colour flow cytometry techniques were used to assess the activation stages of peripheral and intraocular T lymphocytes in uveitis. Increased numbers of T lymphocytes bearing the interleukin-2 (IL-2) receptors were found in intraocular fluids or peripheral blood or both of 35/51 patients with uveitis.
J. Deschênes, S. Kaleta, Devron H. Char
openaire +3 more sources
Lymphocyte‐activation gene‐3, an important immune checkpoint in cancer
Cancer Science, 2016 Immunotherapy has recently become widely used in lung cancer. Many oncologists are focused on cytotoxic T lymphocyte antigen‐4 (CTLA‐4), programmed cell death ligand‐1 (PD‐L1) and programmed cell death‐1 (PD‐1).
Yayi He +7 more
semanticscholar +1 more source
Frontiers in Immunology, 2017 Available evidence indicates that the CD6 lymphocyte surface receptor is involved in T-cell developmental and activation processes, by facilitating cell-to-cell adhesive contacts with antigen-presenting cells and likely modulating T-cell receptor (TCR ...
Esther Carrasco +10 more
doaj +1 more source
Lymphocyte activation gene 3: a novel therapeutic target in chronic lymphocytic leukemia
Haematologica, 2017 A novel therapeutic approach in cancer, attempting to stimulate host anti-tumor immunity, involves blocking of immune checkpoints. Lymphocyte activation gene 3 (LAG3) is an immune checkpoint receptor expressed on activated/exhausted T cells. When engaged
M. Shapiro +9 more
semanticscholar +1 more source
Pathogens and Immunity, 2016 Background: Biological pathways mediating the link between intimate partner violence (IPV) and increased HIV risk remain unexplored. We hypothesized that IPV-induced stress negatively affects HIV systemic immune defenses and aimed to evaluate whether IPV
Ameeta Shivdas Kalokhe +6 more
doaj +1 more source
Physiological Reports, 2021 Regular exercise is associated with changes in peripheral blood mononuclear cell (PBMC) proportions that have enhanced effector functions in young and old adults; however, the effects of acute exercise on PBMC nutrient sensors and metabolic function in ...
Bailey Theall +6 more
doaj +1 more source
Isolation and Activation of Murine Lymphocytes [PDF]
Journal of Visualized Experiments, 2016 B and T cells, with their extremely diverse antigen-receptor repertoires, have the ability to mount specific immune responses against almost any invading pathogen1,2. Understandably, such intricate abilities are controlled by a large number of molecules involved in various cellular processes to ensure timely and spatially regulated immune responses3 ...
Lim, Jun Feng, Berger, Heidi, Su, I-hsin
openaire +4 more sources