Results 41 to 50 of about 1,928,223 (200)

Origin and pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma as revealed by global gene expression analysis [PDF]

open access: yes, 2008
The pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma (NLPHL) and its relationship to other lymphomas are largely unknown. This is partly because of the technical challenge of analyzing its rare neoplastic lymphocytic and histiocytic (L&H ...
Tiacci, Enrico   +29 more
core   +1 more source

Cloned long-term cytolytic T-lymphocyte line with specificity for an immediate-early membrane antigen of murine cytomegalovirus [PDF]

open access: yes, 1986
Long-term cytolytic T-lymphocyte (CTL) lines that are specific for distinct antigens associated with different phases of the replicative cycle of the murine cytomegalovirus (MCMV) were established by cloning of CTL lines derived from lymph nodes of ...
Reddehase, Matthias J.   +2 more
core   +1 more source

Expression of the CD6 T lymphocyte differentiation antigen in normal human brain [PDF]

open access: yes, 1990
Antigens shared by the immune and central nervous systems (CNS) have been described repeatedly. The present study reports the expression of the CD6 lymphocyte differentiation antigen in normal human brain evidenced by immunohistochemistry and Northern ...
Mayer, Barbara   +4 more
core   +1 more source

Efecto de las infecciones oportunistas sobre las subpoblaciones de leucocitos en individuos infectados con el virus de inmunodeficiencia humana tipo 1

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2008
Introducción. La presencia de infecciones por patógenos oportunistas en pacientes con síndrome de inmunodeficiencia adquirida representa un coestímulo para acelerar la progresión de la infección por el VIH-1.
Carlos Julio Montoya   +4 more
doaj   +1 more source

CTPS2 regulates CTP synthetase activity by interacting with CTPS1

open access: yesLife Science Alliance
The human CTP synthetases 1 and 2 associate together and co-localize in large filament–cytoophidium structures. CTPS1 and CTPS2 association results in enzymatic modulation independently of cytoophidia revealing a new regulation mechanism of CTP ...
Norbert Minet   +5 more
doaj   +1 more source

Antibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi

open access: yesFrontiers in Immunology, 2018
Few studies investigate the major protein antigens targeted by the antibody diversity of infected mice with Trypanosoma cruzi. To detect global IgG antibody specificities, sera from infected mice were immunoblotted against whole T. cruzi extracts.
Fabricio Montalvão   +15 more
doaj   +1 more source

Impact of acute exercise on peripheral blood mononuclear cells nutrient sensing and mitochondrial oxidative capacity in healthy young adults

open access: yesPhysiological Reports, 2021
Regular exercise is associated with changes in peripheral blood mononuclear cell (PBMC) proportions that have enhanced effector functions in young and old adults; however, the effects of acute exercise on PBMC nutrient sensors and metabolic function in ...
Bailey Theall   +6 more
doaj   +1 more source

Multidrug transporter activity in lymphocytes [PDF]

open access: yesBritish Journal of Pharmacology, 2004
Multidrug transporters play a dual role in haematopoietic cells, mediating the efflux of xenobiotics and regulating cell migration. For several reasons including the lack of specific antibodies, reports of multidrug transporter distribution on lymphocytes conflict. Murine B cells have been reported to completely lack transporter activity.
James I, Elliott   +2 more
openaire   +2 more sources

Intrahepatic CD8+ lymphocyte trapping during tolerance induction using mushroom derived formulations: A possible role for liver in tolerance induction [PDF]

open access: yes, 2008
AIM: To determine the immunomodulatory effect of Shiitake (a mushroom extract), we tested its effect on liver-mediated immune regulation in a model of immune-mediated colitis. METHODS: Four groups of mice were studied. Colitis was induced by intracolonic
Hershcovici, T.   +11 more
core   +1 more source

Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice

open access: yesNature Communications
De novo synthesis of the pyrimidine, cytidine triphosphate (CTP), is crucial for DNA/RNA metabolism and depends on the CTP synthetases, CTPS1 and −2. Partial CTPS1 deficiency in humans has previously been shown to lead to immunodeficiency, with impaired ...
Claire Soudais   +17 more
doaj   +1 more source

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