Results 51 to 60 of about 359,313 (265)

Early Diagnosis of Pathogen Infection by Cell-Based Activation Immunoassay

Cells, 2019
Diagnostic identification of pathogens is usually accomplished by isolation of the pathogen or its substances, and should correlate with the time and site of infection.
Erez Bar-Haim, Shahar Rotem, Uri Elia, Adi Bercovich-Kinori, Ma’ayan Israeli, Inbar Cohen-Gihon, Ofir Israeli, Noam Erez, Hagit Achdout, Ayelet Zauberman, Moshe Aftalion, Emanuelle Mamroud, Theodor Chitlaru, Ofer Cohen   +13 more
doaj   +1 more source

Lymphocyte Redox Imbalance and Reduced Proliferation after a Single Session of High Intensity Interval Exercise. [PDF]

PLoS ONE, 2016
This study investigated whether an acute session of high-intensity interval training (HIIT) is sufficient to alter lymphocyte function and redox status. Sixteen young healthy men underwent a HIIT session on a cycloergometer, consisting of eight bouts of ...
Rosalina Tossige-Gomes, Karine Beatriz Costa, Vinícius de Oliveira Ottone, Flávio de Castro Magalhães, Fabiano Trigueiro Amorim, Etel Rocha-Vieira   +5 more
doaj   +1 more source

Mechanosensing in T Lymphocyte Activation [PDF]

Biophysical Journal, 2012
Mechanical forces play an increasingly recognized role in modulating cell function. This report demonstrates mechanosensing by T cells, using polyacrylamide gels presenting ligands to CD3 and CD28. Naive CD4 T cells exhibited stronger activation, as measured by attachment and secretion of IL-2, with increasing substrate elastic modulus over the range ...
Judokusumo, E, Tabdanov, E, Kumari, S, Dustin, M, Kam, L   +4 more
openaire   +3 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Effects of immunoregulatory drugs on human peripheral blood T lymphocytes function in vitro [PDF]

Archive of Oncology, 2002
BACKGROUND: The purpose of the study was to evaluate the mode of action of different immunoregulatory drugs in lymphocyte proliferation and activation METHODS: The drugs studied were prednisolone (PRED), cyclosporin A (CsA) the recombination of PRED and ...
Hatzistilianou Marija, Hitoglou Soultana, Gougoustamou Despina, Kotsis Alexandros, Kallinderes Athanasios, Athanassiadou Fanni, Catriu Dorothea   +6 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

THE IMMUNOCOMPETENT CELLS RECEPTORS RESEARCH UNDER EXPERIMENTAL INFLUENZA INFECTION IN VITRO

Инфекция и иммунитет, 2015
Introduction. It is known that interferon is a cytokine and is a substantial part of the immune system necessary for antigenic challenge immune response full expression. Also it is considered that every antigen is an interferon inducer.
A. N. Lisakov, F. G. Nagieva, E. P. Barkova, L. A. Gaiderova, A. Y. Fedotov, V. G. Nikulina, M. V. Gavrilova   +6 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Wire Injury-Induced Moderate Aortic Valve Stenosis in Mice Is Accompanied by a Chronic Systemic Inflammatory Reaction

Cells
Background/Objectives: While the presence of inflammatory processes in stenotic aortic valves is acknowledged, no systematic characterization of the systemic immune reaction upon aortic valve stenosis (AS) has been performed yet.
Katrin Becker
doaj   +1 more source

Human Plasma-like Medium Improves T Lymphocyte Activation

iScience, 2020
Summary: T lymphocytes are critical for effective immunity, and the ability to study their behavior in vitro can facilitate major insights into their development, function, and fate.
Michael A. Leney-Greene, Arun K. Boddapati, Helen C. Su, Jason R. Cantor, Michael J. Lenardo   +4 more
doaj   +1 more source