Results 21 to 30 of about 1,928,223 (200)

Silver Nanoparticle-Induced Lymphocyte Activation in Zebrafish [PDF]

Nanomedicine Research Journal, 2022
Silver nanoparticles (Ag-NPs) are among the most widely used nanomaterials in the world. Nanotoxicological data on these additives remain unclear. The aim of this study is to evaluate the in vivo effects of Ag-NPs bioaccumulation on the hematological ...
Tarek Mahjoub, Saoussene Chernine, Rym Lahmar, Victor Gourain, Mohamed-Sofiane Mahjoub, Ahmed Rejeb, Mohamed-Néjib Romdane, Samir Ben Romdhane, Hafedh Abdelmelek   +8 more
doaj   +1 more source

Continuous Modeling of T CD4 Lymphocyte Activation and Function

Frontiers in Immunology, 2021
T CD4+ cells are central to the adaptive immune response against pathogens. Their activation is induced by the engagement of the T-cell receptor by antigens, and of co-stimulatory receptors by molecules also expressed on antigen presenting cells. Then, a
David Martínez-Méndez, Luis Mendoza, Luis Mendoza, Carlos Villarreal, Carlos Villarreal, Leonor Huerta   +5 more
doaj   +1 more source

Lymphocyte activation gene-3 : the expression and function in the immune system [PDF]

, 2006
Lymphocyte activation gene-3 (LAG-3) is the structural homologue of a well-known TCR co-receptor CD4. Recently, it has been suggested that LAG-3 might play a role in modulation of immune response, by being a negative regulator of T cell activation. To
Kisielow, Malgorzata
core   +1 more source

Utilizing T-Lymphocyte Activation-Related Cytokines to Predict Non-Responsiveness to Treatment in Pediatric Kawasaki Disease. [PDF]

Pediatric Health Med Ther
Bei Ye,1 Jiying Xiao,2 Caiyun Zhang3 1Department of Pediatrics, Hangzhou Children’s Hospital, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Respiratory Medicine, Hangzhou Children’s Hospital, Hangzhou, Zhejiang, People’s Republic of ...
Ye B, Xiao J, Zhang C.
europepmc   +2 more sources

Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction

Nature Communications, 2021
Chimeric antigen receptor engineering in T cells has been shown to be of great potential therapeutic benefit in a range of immune pathologies, although the functionality of such cell therapies can be limited due to tonic signalling and the induction of ...
Baptiste Lamarthée, Armance Marchal, Soëli Charbonnier, Tifanie Blein, Juliette Leon, Emmanuel Martin, Lucas Rabaux, Katrin Vogt, Matthias Titeux, Marianne Delville, Hélène Vinçon, Emmanuelle Six, Nicolas Pallet, David Michonneau, Dany Anglicheau, Christophe Legendre, Jean-Luc Taupin, Ivan Nemazanyy, Birgit Sawitzki, Sylvain Latour, Marina Cavazzana, Isabelle André, Julien Zuber   +22 more
doaj   +1 more source

Deriving a germinal center lymphocyte migration model from two-photon data [PDF]

, 2008
Recently, two-photon imaging has allowed intravital tracking of lymphocyte migration and cellular interactions during germinal center (GC) reactions. The implications of two-photon measurements obtained by several investigators are currently the subject ...
Michael Meyer-Hermann, Garin, A, Marie Kosco-Vilbois, Figge, MT, Figge, Marc Thilo, Marc Thilo Figge, Meyer-Hermann, M, Kosco-Vilbois, M, Kosco-Vilbois, Marie, Gunzer, Matthias, Garin, Alexandre, Kai-Michael Toellner, Meyer-Hermann, Michael (Prof. Dr.), Alexandre Garin, Gunzer, M, Matthias Gunzer, Toellner, Kai-Michael   +16 more
core   +1 more source

Loss of RASGRP1 in humans impairs T‐cell expansion leading to Epstein‐Barr virus susceptibility

EMBO Molecular Medicine, 2018
Inherited CTPS1, CD27, and CD70 deficiencies in humans have revealed key factors of T‐lymphocyte expansion, a critical prerequisite for an efficient immunity to Epstein–Barr virus (EBV) infection.
Sarah Winter, Emmanuel Martin, David Boutboul, Christelle Lenoir, Sabah Boudjemaa, Arnaud Petit, Capucine Picard, Alain Fischer, Guy Leverger, Sylvain Latour   +9 more
doaj   +1 more source

Polysaccharide of Atractylodes macrocephala Koidz (PAMK) Alleviates Cyclophosphamide-induced Immunosuppression in Mice by Upregulating CD28/IP3R/PLCγ-1/AP-1/NFAT Signal Pathway

Frontiers in Pharmacology, 2020
The polysaccharide of Atractylodes macrocephala Koidz (PAMK) is recognized as an immune enhancer, with anti-cancer, anti-tumour, lymphocyte-activating and lymphocytes proliferation-inducing effects.
Xuelian Xiang, Nan Cao, Feiyue Chen, Long Qian, Yifei Wang, Yunmao Huang, Yunbo Tian, Danning Xu, Wanyan Li   +8 more
doaj   +1 more source

Alterations in immunophenotype and metabolic profile of mononuclear cells during follow up in children with multisystem inflammatory syndrome (MIS-C)

Frontiers in Immunology, 2023
IntroductionAlthough children seem to be less susceptible to COVID-19, some of them develop a rare but serious hyperinflammatory condition called multisystem inflammatory syndrome in children (MIS-C).
Andreja Nataša Kopitar, Jernej Repas, Larisa Janžič, Maša Bizjak, Tina Tajnšek Vesel, Nina Emeršič, Mojca Zajc Avramovič, Alojz Ihan, Tadej Avčin, Tadej Avčin, Mojca Pavlin, Mojca Pavlin   +11 more
doaj   +1 more source

Prognostic impact of a lymphocyte activation-associated gene signature in GBM based on transcriptome analysis [PDF]

PeerJ, 2021
Background Glioblastoma multiforme (GBM) is a highly, malignant tumor of the primary central nervous system. Patients diagnosed with this type of tumor have a poor prognosis.
Yujia Lan, Erjie Zhao, Xinxin Zhang, Xiaojing Zhu, Linyun Wan, Suru A, Yanyan Ping, Yihan Wang   +7 more
doaj   +2 more sources