Modification of H-2 Antigenic Sites by Enzymatic Treatment Influences Virus-Specific Target Cell Lysis [PDF]
Vaccinia virus-infected cells were treated enzymatically to remove H-2 antigenic sites. The effect of this procedure on virus-specific cell-mediated cytolysis (CMC) and virus-specific antibody-mediated cytolysis (AMC) was tested. Due to the inhibition of
Ertl, H., Koszinowski, Ulrich H.
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Infectious Lymphocytes in Lymphocytic Choriomeningitis Virus Carrier Mice
The infectivity of blood and lymphoid organs of mice persistently infected with lymphocytic choriomeningitis virus was found to be predominantly associated with lymphocytes and both T and B cells were infectious. A hypothesis is presented in which it is assumed that lymphocytes in carrier mice are infected via their LCM virus-specific antigen receptors,
M, Popescu, J, Löhler, F, Lehmann-Grube
openaire +2 more sources
MATERNAL HEALTH AND ZOONOSIS [PDF]
Master of Public HealthPublic Health Interdepartmental ProgramDavid G. RenterI completed my field experience at the Department of Public Health (DPH) at the Fort Riley Army Installation, Kansas.
Hoffner, Jull J. Speier
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PD-1 signaling promotes control of chronic viral infection by restricting type-I-interferon-mediated tissue damage [PDF]
Immune responses are essential for pathogen elimination but also cause tissue damage, leading to disease or death. However, it is unclear how the host immune system balances control of infection and protection from the collateral tissue damage.
Egawa, Takeshi +2 more
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Immune Exhaustion: Past Lessons and New Insights from Lymphocytic Choriomeningitis Virus
Lymphocytic choriomeningitis virus (LCMV) is a paradigm-forming experimental system with a remarkable track record of contributing to the discovery of many of the fundamental concepts of modern immunology.
Shannon M. Kahan, Allan J. Zajac
doaj +1 more source
CD8β knockout mice mount normal anti-viral CD8+ T cell responses—but why? [PDF]
It has been shown previously that CD8β in vitro increases the range and the sensitivity of antigen recognition and in vivo plays an important role in the thymic selection of CD8+ T cells.
Angelov, Georgi S. +2 more
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La schizophrénie touche aussi les enfants et les adolescents : une des modalités de leur prise en charge est assurée par le CTJA [Centre thérapeutique de jour pour adolescents] [PDF]
1% des schizophrénies se déclenchent avant l'âge de 10 ans. 20%, une sur cinq, commencent avant l'âge de 18 ans. Et dans 40% des cas de schizophrénie avérée, les premiers signes étaient apparus avant 18 ans.
Dunand, Fabien, Holzer, Laurent
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The re-emergence and evolution of lymphocytic choriomeningitis virus in Germany
Introduction: Lymphocytic choriomeningitis virus (LCMV; species Mammarenavirus choriomeningitidis), a zoonotic pathogen transmitted by house mice (Mus musculus), is the only globally distributed arenavirus.
Mr Calvin Mehl +16 more
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Pseudotyped Lentiviral Vectors: One Vector, Many Guises [PDF]
Viruses have evolved specialized molecular mechanisms to transfer their genome efficiently into host cells. Viruses can be repurposed into viral vectors to achieve controlled gene transfer to desired cells.
Joglekar, Alok V., Sandoval, Salemiz
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Human Infection with Lymphocytic Choriomeningitis Virus
Leslie L. Barton
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