Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage [PDF]
Background Several arenaviruses cause severe hemorrhagic fever and aseptic meningitis in humans for which no licensed vaccines are available. A major obstacle for vaccine development is pathogen heterogeneity within the Arenaviridae family.
Maya F Kotturi +12 more
core +2 more sources
Lymphocytic Choriomeningitis Virus–associated Meningitis, Southern Spain
Lymphocytic choriomeningitis virus (LCMV) was detected in 2 patients with acute meningitis in southern Spain within a 3-year period. Although the prevalence of LCMV infection was low (2 [1.3%] of 159 meningitis patients), it represents 2.9% of all ...
Mercedes Pérez-Ruiz +8 more
doaj +1 more source
Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis. [PDF]
The presence of the endogenous <i>Leishmania</i> RNA virus 1 (LRV1) replicating stably within some parasite species has been associated with the development of more severe forms of leishmaniasis and relapses after drug treatment in humans ...
Beverley, S.M. +12 more
core +1 more source
Mouse-to-Human Transmission of Variant Lymphocytic Choriomeningitis Virus
A case of lymphocytic choriomeningitis virus (LCMV) infection led to investigation of the reservoir. LCMV was detected in mice trapped at the patient's home, and 12 isolates were recovered.
Sébastien Emonet +4 more
doaj +1 more source
Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone [PDF]
Lymphocytic choriomeningitis virus (LCMV) can be transmitted through congenital infection, leading to persistent infection of numerous organ systems including the central nervous system (CNS).
Klein, Robyn S +2 more
core +8 more sources
Host Range and Genetic Diversity of Arenaviruses in Rodents, United Kingdom
During a study to extend our knowledge of the host range and genetic diversity of arenaviruses in Great Britain, 66 of 1,147 rodent blood samples tested for antibody, and 127 of 482 tested by PCR, were found positive. All sequences most closely resembled
Kim R. Blasdell +4 more
doaj +1 more source
Lymphocytic Choriomeningitis Virus Meningitis, New York, NY, USA, 2009
We describe a case of lymphocytic choriomeningitis virus (LCMV) meningitis in a New York, NY, resident who had no apparent risk factors. Clues leading to the diagnosis included aseptic meningitis during winter and the finding of hypoglycorrachia and ...
Deborah S. Asnis +5 more
doaj +1 more source
Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]
International audienceThe Dark Energy Camera has captured a large set of images as part of Science Verification (SV) for the Dark Energy Survey (DES). The SV footprint covers a large portion of the outer Large Magellanic Cloud (LMC), providing photometry
Abbott, T. M. C. +54 more
core +4 more sources
Die Rolle des Signalpeptids für die Reifung des Lassavirus Glykoproteins [PDF]
Das Oberflächenglykoprotein des Lassavirus ist ein Typ 1-Membranprotein. Es wird als Vorläufer präGP-C synthetisiert und posttranslational mit N-Glykanen modifiziert.
Buckel, Wolfgang (Prof. Dr.) +1 more
core +1 more source
Trace-Forward Investigation of Mice in Response to Lymphocytic Choriomeningitis Virus Outbreak
During follow-up of a 2012 US outbreak of lymphocytic choriomeningitis virus (LCMV), we conducted a trace-forward investigation. LCMV-infected feeder mice originating from a US rodent breeding facility had been distributed to >500 locations in 21 states.
Laura Edison +9 more
doaj +1 more source

