Oestrogen, an evolutionary conserved regulator of T cell differentiation and immune tolerance in jawed vertebrates? [PDF]
, 2018 In teleosts, as in mammals, the immune system is tightly regulated by sexual steroid hormones, such as oestrogens. We investigated the effects of 17β-oestradiol on the expression of several genes related to T cell development and resulting T cell ...
Duflot, Aurélie +5 more
core +3 more sources
The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled
Frontiers in Immunology, 2023 Marine fish larvae often experience high mortality unrelated to predation during early life stages, and farmed ballan wrasse (Labrus bergylta) is no exception.
Angela Etayo +6 more
doaj +1 more source
Innate lymphoid cells and cancer
Nature Immunology, 2022 The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and ILC3, which participate in immune responses to virus, bacteria, parasites and transformed cells.
Nicolas Jacquelot +3 more
semanticscholar +1 more source
A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus [PDF]
, 1976 A quantitative Abelson murine leukemia virus (A-MuLV) lymphoid cell transformation assay has been developed using a semisolid agarose culture system. Under these conditions lymphoid cell transformation was shown to vary linearly with the dose of A-MuLV ...
Baltimore, David, Rosenberg, Naomi
core +1 more source
Regulation of myeloid and lymphoid cell development by O-glycans on Notch
Frontiers in Molecular Biosciences, 2022 Notch signaling via NOTCH1 stimulated by Delta-like ligand 4 (DLL4) is required for the development of T cells in thymus, and NOTCH2 stimulated by Notch ligand DLL1 is required for the development of marginal zone (MZ) B cells in spleen.
Pamela Stanley, Ankit Tanwar
doaj +1 more source
Development and function of regulatory innate lymphoid cells
Frontiers in Immunology, 2022 Innate lymphoid cells (ILCs) are a critical element of the innate immune system and are potent producers of pro-inflammatory cytokines. Recently, however, the production of the anti-inflammatory cytokine IL-10 has been observed in all ILC subtypes (ILC1s,
Christopher M. Thomas +3 more
doaj +1 more source
Potential for Cell-Mediated Immune Responses in Mouse Models of Pelizaeus-Merzbacher Disease
Brain Sciences, 2013 Although activation of the innate and adaptive arms of the immune system are undoubtedly involved in the pathophysiology of neurodegenerative diseases, it is unclear whether immune system activation is a primary or secondary event.
Cherie M. Southwood +3 more
doaj +1 more source
Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]
, 2018 Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO +8 more
core +1 more source
Romanian Journal of Laboratory Medicine, 2023 Castleman’s disease is a benign lymphoproliferative disorder. The coexistence of Hodgkin’s lymphoma and multicentric Castle-man’s disease is a rare phenomenon. We discuss a case of a 48-year-old female patient who had been in the records of the Colentina
Andreescu Mihaela +8 more
doaj +1 more source
Altered expression of DNMT3A gene in B-cell acute lymphoblastic leukemia by mercaptopurine
فصلنامه دانشگاه علوم پزشکی جهرم, 2021 Introduction: Current medications used for acute lymphoblastic leukemia (ALL) such as mercaptopurine target molecular factors involved in its onset and progression including DNA methyltransferases (DNMTs) because these enzymes are implicated in ...
Seyedhossein Hekmatimoghaddam +4 more
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