Results 31 to 40 of about 693,895 (386)

Immunophenotypic Aberrancies in Acute Leukemia: A Tertiary Care Centre Experience

Oman Medical Journal, 2021
Objectives: Acute leukemias (AL) are a heterogeneous group of hematological malignancies with the presence of 20% or more blasts in the peripheral blood or bone marrow.
Monika Gupta, Lovekesh Monga, Dimple Mehrotra, Sonia Chhabra, Shivani Singhal, Rajeev Sen   +5 more
doaj   +1 more source

The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled

Frontiers in Immunology, 2023
Marine fish larvae often experience high mortality unrelated to predation during early life stages, and farmed ballan wrasse (Labrus bergylta) is no exception.
Angela Etayo, Angela Etayo, Kai K. Lie, Reidun M. Bjelland, Ivar Hordvik, Aina-Cathrine Øvergård, Øystein Sæle   +6 more
doaj   +1 more source

Fluoroquinolone prophylaxis does not increase risk of neuropathy in children with acute lymphoblastic leukemia

Cancer Medicine, 2020
Background Fluoroquinolone antibiotics are frequently utilized in pediatric oncology patients as prophylaxis or step‐down therapy following broad spectrum beta‐lactam therapy for febrile neutropenia.
Seth E. Karol, Yilun Sun, Li Tang, Ching‐Hon Pui, Jose Ferrolino, Kim J. Allison, Shane J. Cross, William E. Evans, Kristine R. Crews, Sima Jeha, Joshua Wolf   +10 more
doaj   +1 more source

The Role of T Lymphocytes in Skeletal Muscle Repair From Traumatic and Contraction-Induced Injury

Frontiers in Physiology, 2018
Skeletal muscle is prone to damage from a range of stimuli, and initiates a robust repair process that requires the participation of immune cells. Among the more well characterized immune cells involved in muscle repair are those of the myeloid lineage ...
Michael R. Deyhle, Robert D. Hyldahl
doaj   +1 more source

PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]

, 2002
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Barillas-Mury, C., Hoover, E.A., Keulen, L.J.M., van, Langeveld, J.P.M., Miller, M.W., Oesch, B., Sigurdson, C.J.   +6 more
core   +2 more sources

The frequency of aberrant lymphoid antigens expression in 202 Iraqi patients with de novo acute myeloid leukemia

Iraqi Journal of Hematology, 2017
Background: Immunophenotyping improves both accuracy and reproducibility of acute leukemia classification and is considered, particularly useful for identifying acute myeloid leukemia (AML) with lymphoid marker expression.
Wafaa Mohammed Al-Anizi, Mohammed Abdul Rassoul Al-Mashta   +1 more
doaj   +1 more source

Antigen-presenting cells and antigen presentation in tertiary lymphoid organs [PDF]

, 2016
Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures.
Bedaj, Marija, Benson, Robert A., Hughes, Catherine E., Maffia, Pasquale   +3 more
core   +1 more source

Altered expression of DNMT3A gene in B-cell acute lymphoblastic leukemia by mercaptopurine

فصلنامه دانشگاه علوم پزشکی جهرم, 2021
Introduction: Current medications used for acute lymphoblastic leukemia (ALL) such as mercaptopurine target molecular factors involved in its onset and progression including DNA methyltransferases (DNMTs) because these enzymes are implicated in ...
Seyedhossein Hekmatimoghaddam, Tahereh Ahmadi, Fatemeh Pourrajab, Ali Dehghani Firoozabadi, Kolan Rahmani   +4 more
doaj  

Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies

Journal for ImmunoTherapy of Cancer, 2021
Background Full application of cytokines as oncoimmunotherapeutics requires identification of optimal regimens. Our initial effort with intravenous bolus recombinant human interleukin-15 (rhIL-15) was limited by postinfusional reactions.
Thomas A Waldmann, Kevin C Conlon, Sigrid P Dubois, Milos D Miljkovic, Thomas A Fleisher, Stefania Pittaluga, Jennifer Hsu-Albert, Bonita R Bryant, Michael N Petrus, Liyanage P Perera, Jürgen R Müller, Joanna H Shih   +11 more
doaj   +1 more source

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.

New England Journal of Medicine, 2011
We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with CD137 (a costimulatory receptor in T cells [4-1BB]) and CD3-zeta (a signal-transduction component of the T-cell antigen ...
D. Porter, B. Levine, M. Kalos, A. Bagg, C. June   +4 more
semanticscholar   +1 more source