Altered expression of DNMT3A gene in B-cell acute lymphoblastic leukemia by mercaptopurine
Introduction: Current medications used for acute lymphoblastic leukemia (ALL) such as mercaptopurine target molecular factors involved in its onset and progression including DNA methyltransferases (DNMTs) because these enzymes are implicated in ...
Seyedhossein Hekmatimoghaddam+4 more
doaj
PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Barillas-Mury, C.+6 more
core +2 more sources
Background Full application of cytokines as oncoimmunotherapeutics requires identification of optimal regimens. Our initial effort with intravenous bolus recombinant human interleukin-15 (rhIL-15) was limited by postinfusional reactions.
Thomas A Waldmann+11 more
doaj +1 more source
MIXED HYALINE VASCULAR AND PLASMA CELL TYPE CASTLEMAN’S DISEASE: REPORT OF A CASE [PDF]
Castleman’s disease (angiofollicular lymphoid hyperplasia) includes a heterogeneous group of lymphoproliferative disorders. The cause of this disease remains uncertain.
F. Asgarani+4 more
doaj +1 more source
Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]
Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO+8 more
core +1 more source
Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation [PDF]
Objective: Heavy post-transplant immunosuppression may contribute to long-term immunosuppression dependence by subverting tolerogenic mechanisms; thus, we sought to determine if this undesirable consequence could be mitigated by pretransplant lymphoid ...
Abhay N. Vats+52 more
core +1 more source
Tertiary lymphoid organs in central nervous system autoimmunity [PDF]
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core +1 more source
An unusual initial presentation of mantle cell lymphoma arising from the lymphoid stroma of warthin tumor. [PDF]
BackgroundWarthin tumors presenting concomitantly with a lymphoma is vanishingly rare with only 15 reported cases in English literature. Herein, we report an unusual initial presentation of a mantle cell lymphoma involving the lymphoid stroma of a ...
Arcega, Ramir S+5 more
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Lymphoid organogenesis in brief [PDF]
The recognition that lymphocytes existed in different varieties and that lymphoid organs were important for their differentiation greatly influenced immunological research. The growing awareness that started in the mid-fifties of the previous century has shifted the emphasis of immunology from a molecular, mostly serological science to the cell ...
Vondenhoff, Mark F R+2 more
openaire +4 more sources
The effect of helper virus on Abelson virus-induced transformation of lymphoid cells [PDF]
Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses.
Baltimore, David, Rosenberg, Naomi
core +2 more sources