Results 11 to 20 of about 78,214 (186)

Bacteria-driven peribronchial lymphoid neogenesis in bronchiectasis and cystic fibrosis [PDF]

European Respiratory Journal, 2017
We aimed to characterise lymphoid neogenesis in bronchiectasis and cystic fibrosis (CF) lungs and to examine the role of bacterial infection.Lymphoid aggregates were examined using immunohistochemical staining and morphometric analysis in surgical lung sections obtained from nonsmokers and patients with bronchiectasis or CF.
Diane Damotte, Lhousseine Touqui, Lucile Regard   +2 more
exaly   +5 more sources

Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases [PDF]

Cancer Research, 2012
Abstract Lymphoid neogenesis, or the development of lymphoid structures in nonlymphoid organs, is frequently observed in chronically inflamed tissues, during the course of autoimmune, infectious, and chronic graft rejection diseases, in which a sustained lymphocyte activation occurs in the presence of persistent antigenic stimuli. The
Teofila Seremet, Pierre G Coulie, Nicolas van Baren   +2 more
exaly   +4 more sources

Ectopic lymphoid neogenesis in psoriatic arthritis [PDF]

Annals of the Rheumatic Diseases, 2007
Ectopic lymphoid neogenesis (LN) occurs in rheumatoid synovium, where it is thought to drive local antigen-dependent B cell development and autoantibody production. This process involves the expression of specific homing chemokines and the development of high endothelial venules (HEV).To investigate whether these mechanisms occur in psoriatic arthritis
Cañete, Juan D., Santiago, Begoña, Cantaert, Tineke, Sanmartí, Raimon, Palacin, Antonio, Celis, Raquel, Graell, Eduard, Gil-Torregrosa, Beatriz, Baeten, Dominique, Pablos, José L.   +9 more
openaire   +4 more sources

Chronic inflammatory disease, lymphoid tissue neogenesis and extranodal marginal zone B-cell lymphomas [PDF]

Haematologica, 2009
Chronic autoimmune or pathogen-induced immune reactions resulting in lymphoid neogenesis are associated with development of malignant lymphomas, mostly extranodal marginal zone B-cell lymphomas (MZBCLs).
Richard J. Bende, Febe van Maldegem, Carel J.M. van Noesel   +2 more
doaj   +3 more sources

Rejection of Tracheal Allograft by Intrapulmonary Lymphoid Neogenesis in the Absence of Secondary Lymphoid Organs

Transplantation, 2012
Obliterative bronchiolitis after lung transplantation is associated with intrapulmonary lymphoid neogenesis. The purpose of this study was to examine the role of lymphoid neogenesis, especially its relationship with secondary lymphoid organs (SLOs) in allograft airway rejection.A murine intrapulmonary tracheal transplant model and a conventional ...
Wagnetz, D, Sato, M, Hirayama, S, Matsuda, Y, Juvet, S, Yeung, J, Guan, Z, Zhang, L, Liu, M, Waddell, T, Keshavjee, S   +10 more
openaire   +3 more sources

B Lymphocyte Autoimmunity in Rheumatoid Synovitis Is Independent of Ectopic Lymphoid Neogenesis [PDF]

The Journal of Immunology, 2008
Abstract B lymphocyte autoimmunity plays a crucial role in the pathogenesis of rheumatoid arthritis. The local production of autoantibodies and the presence of ectopic lymphoid neogenesis in the rheumatoid synovium suggest that these dedicated microenvironments resembling canonical lymphoid follicles may regulate the initiation and ...
Cantaert, Tineke, Kolln, Johanna, Timmer, Trieneke, van der Pouw Kraan, Tineke C., Vandooren, Bernard, Thurlings, Rogier M., Cañete, Juan D., Catrina, Anca I., Out, Theo, Verweij, Cor L., Zhang, Yiping, Tak, Paul P., Baeten, Dominique, van der Pouw Kraan, C.T.M.   +13 more
openaire   +4 more sources

Role of lymphotoxin-α in cigarette smoke-induced inflammation and lymphoid neogenesis [PDF]

European Respiratory Journal, 2009
In chronic obstructive pulmonary disease (COPD), chronic inflammation is accompanied by peribronchial lymphoid aggregates. Lymphotoxin (LT)-α, crucial in secondary lymphoid organogenesis, may be involved in lymphoid neogenesis.We examined cigarette smoke (CS)-induced pulmonary lymphoid neogenesis and inflammationin vivoin LTα knockout (LTα-/-) and wild-
Demoor, Tine, Bracke, Ken, Maes, Tania, VANDOOREN, BERNARD, Elewaut, Dirk, Pilette, Charles, Joos, Guy, Brusselle, Guy   +7 more
openaire   +4 more sources

Chronic inflammation caused by lymphotoxin is lymphoid neogenesis. [PDF]

Journal of Experimental Medicine, 1996
In presenting a unifying concept for chronic inflammation and lymphoid organogenesis, we suggest that lymphotoxin's (LT, LT-alpha, TNF-beta) crucial role in these processes is pivotal and similar. Chronic inflammatory lesions that developed in the kidney and pancreas at the sites of transgene expression in rat insulin promoter-LT (RIP-LT) mice ...
A Campos-Neto
exaly   +3 more sources

Erratum: Molecular, Immunological, and Clinical Features Associated With Lymphoid Neogenesis in Muscle Invasive Bladder Cancer [PDF]

Frontiers in Immunology, 2022
Frontiers Production Office
doaj   +2 more sources

Global research landscape and emerging trends of tertiary lymphoid structures in autoimmune diseases: a bibliometric analysis [PDF]

Frontiers in Immunology
BackgroundTertiary lymphoid structures (TLSs) are increasingly regarded as important local immune niches in chronic inflammation and autoimmunity.
Jiaqi Wang, Yiyuanzi Zhao, Xixuan Chen, Tianshu Dong, Zhiyi Feng, Zhongmian Zhang, Zhihong Li   +6 more
doaj   +2 more sources