Results 51 to 60 of about 23,347 (241)
This paper focuses on selenium, selenocysteine, and GPX4, elaborating on their metabolic functions and mechanisms in mediating immune regulation through autophagy in solid tumors. It explores the characteristics of selenium metabolism in tumors and the roles of related enzymes, providing new directions for cancer treatment.
Liang Yang +7 more
wiley +1 more source
Immunotherapy of COVID-19: Inside and Beyond IL-6 Signalling
Acting on the cytokine cascade is key to preventing disease progression and death in hospitalised patients with COVID-19. Among anti-cytokine therapies, interleukin (IL)-6 inhibitors have been the most used and studied since the beginning of the pandemic.
Gaetano Zizzo +7 more
doaj +1 more source
216 Jewish Hospital of St. Louis [PDF]
https://digitalcommons.wustl.edu/bjc_216/1182/thumbnail ...
core +1 more source
Monoclonal Antibodies as Immune Modulators for Cancer Therapy
Monoclonal antibodies may modulate immune and/or biological responses alone, or as carriers of specific agents. Monoclonal antibodies directed against tumours may be indirectly cytotoxic by modulation of antibody-dependent, cell-mediated cytotoxicity or ...
Robert O Dillman
doaj +1 more source
Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
University Hospital, Evans Memorial Department of Clinical Research and Preventive Medicine
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Ultra‐Processed Foods and Markers of Systemic Inflammation in Children
Illustration showing the association between ultra‐processed foods intake and systemic inflammation, measured with cytokines levels in children. ABSTRACT Diets high in ultra‐processed foods (UPF) have been associated with negative health outcomes in adults; however, UPF's impact on children's health and their underlying mechanisms remain underexplored,
Camila Awad +8 more
wiley +1 more source
Research progress of active polypeptides of Cordyceps militaris
It is recognized at home and abroad that Cordyceps militaris is a fungus that can be edible and used for medicinal application, and also a common cordyceps taishanensis that is widely distributed and with very high medicinal value in China.
Xu Guangyu +5 more
doaj +1 more source
The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts
The immune suppressants cyclosporin A (CsA) and tacrolimus (FK506) are used worldwide in transplantation medicine to suppress graft rejection. Both CsA and FK506 inhibit the phosphatase calcineurin (CN) whose activity controls the immune receptor ...
Johannes Baur +12 more
doaj +1 more source
Induction of IL 2 receptor expression and cytotoxicity of thymocytes by stimulation with TCF1 [PDF]
We investigated the role of T cell cytotoxicity inducing factor 1 (TCF1) in the induction of a cytotoxic T cell response. We found that help-deficient thymocyte cultures supplied with saturating amounts of purified IL 2 did not develop CTL in a 5-day ...
Diamantstein, T. +6 more
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Suppression of allograft rejection with FK506: I. prolonged cardiac and liver survival in rats following short-course therapy [PDF]
Heterotopic heart and orthotopic liver grafts from ACI donors were transplanted to Lewis rat recipients that were treated with a 3 (or 4) day course of FK506 IM that was started on postoperative day 0, 2, 3, 4, 5, or 6.
Cramer, DV +5 more
core +1 more source

