Results 71 to 80 of about 21,932 (240)

Accumulation of Oxidized Low-Density Lipoprotein in Psoriatic Skin and Changes of Plasma Lipid Levels in Psoriatic Patients

Mediators of Inflammation, 2007
Background. Psoriasis is a chronic inflammatory skin disease characterized by an accelerated turnover of epidermal cells and an incomplete differentiation in epidermis with lesion. However, the exact etiology of psoriasis is unknown.
Nilgun Solak Tekin, Ishak Ozel Tekin, Figen Barut, Emine Yilmaz Sipahi   +3 more
doaj   +1 more source

2′‐Fucosyllactose Modulates the Intestinal Immune Response to Gut Microbiota and Buffers Experimental Colitis in Mice: An Integrating Investigation of Colonic Proteomics and Gut Microbiota Analysis

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
2′‐fucosyllactose prevented DSS‐induced intestinal inflammatory damage through exerting prebiotic capacity and regulating the intestinal immune response to gut microbiota. ABSTRACT Inflammatory bowel disease (IBD), a recurrent gastrointestinal disease, is characterized by dysbiosis and inflammation.
Jiamin Dong, Minyan Qian, Dong Zhou, Aoshuang Zhu, Wenting Zhang   +4 more
wiley   +1 more source

CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. [PDF]

, 1992
Activation of an immune response requires intercellular contact between T lymphocytes and antigen-presenting cells (APC). Interaction of the T cell antigen receptor (TCR) with antigen in the context of major histocompatibility molecules mediates signal ...
Fraser, JD, Newton, ME, Weiss, A
core  

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

Advanced Science, Volume 12, Issue 18, May 15, 2025.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang, Qingqing Feng, Chuanming Zheng, Yuanqiang Li, Xinyang Ge, Tiefeng Jin, Gaofeng Hu, Zhuo Tan, Jiafeng Wang, Jiajie Xu, Liehao Jiang, Dan Wang, Zhangguo Ying, Xiao Zhao, Keman Cheng, Qinglin Li, Minghua Ge   +16 more
wiley   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

Cell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou, Yifeng Chen, Yuhao Ba, Hui Xu, Anning Zuo, Shutong Liu, Yuyuan Zhang, Siyuan Weng, Yuqing Ren, Peng Luo, Quan Cheng, Lulu Zuo, Shanshan Zhu, Xing Zhou, Chuhan Zhang, Yukang Chen, Xinwei Han, Teng Pan, Zaoqu Liu   +18 more
wiley   +1 more source

Crosstalk between T lymphocyte and extracellular matrix in tumor microenvironment

Frontiers in Immunology
The extracellular matrix (ECM) is a complex three-dimensional structure composed of proteins, glycans, and proteoglycans, constituting a critical component of the tumor microenvironment.
Die Lv, Yujie Fei, Hongli Chen, Junfeng Wang, Wenwen Han, Bomiao Cui, Yun Feng, Ping Zhang, Jiao Chen   +8 more
doaj   +1 more source

V-region-related and -unrelated immunosupression accompanying infections

Memorias do Instituto Oswaldo Cruz, 1992
This paper discusses current evidence for the relationship between polyclonal lymphocyte activation, specific immunossupression with decreased resistance, and autoimmune pathology, that are all often found associated with infections by a variety of virus,
Mario Arala-Chaves, M. Regina D'Imperio Lima, Antonio Coutinho, Claudia Penna-Rossi, Paola Minoprio   +4 more
doaj   +1 more source

Biological processes and factors involved in soft and hard tissue healing

Periodontology 2000, Volume 97, Issue 1, Page 16-42, February 2025.
Abstract Wound healing is a complex and iterative process involving myriad cellular and biologic processes that are highly regulated to allow satisfactory repair and regeneration of damaged tissues. This review is intended to be an introductory chapter in a volume focusing on the use of platelet concentrates for tissue regeneration.
Mark Bartold, Saso Ivanovski
wiley   +1 more source

The epigenetic drug Trichostatin A ameliorates experimental autoimmune encephalomyelitis via T cell tolerance induction and impaired influx of T cells into the spinal cord

Neurobiology of Disease, 2017
Multiple sclerosis is a T cell mediated chronic demyelinating disease of the central nervous system. Although currently available therapies reduce relapses, they do not facilitate tolerization of myelin antigen-specific T lymphocytes to ensure prolonged ...
Arathi Jayaraman, Advait Soni, Bellur S. Prabhakar, Mark Holterman, Sundararajan Jayaraman   +4 more
doaj   +1 more source

H1N1 with fatal viral septicemia in a normal child: A case report

Respiratory Medicine Case Reports, 2020
Background: Regardless of the agent, the inflammatory response is interconnected with infection. Mostly the initial response to infection is severe sepsis and characterized by a pro-inflammatory state, which then progresses to an anti-inflammatory state ...
Ahmed Rezk Ahmed, M.D.
doaj   +1 more source