Results 91 to 100 of about 141,580 (256)

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price   +12 more
wiley   +1 more source

Causation in Occupational Disease: Balancing Epidemiology, Law and Manufacturer Conduct [PDF]

open access: yes, 1998
Drs. Lynch & Henefin examine evolution of disease causation theory and its impact on public health, as well as how these relate to the courtroom admissibility of expert opinion ...
Henifin, Mary S., Lynch, Richard M.
core   +1 more source

Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old. [PDF]

open access: yes, 2014
BACKGROUND: In clinical practice, unexpected diagnosis of colorectal cancer in young patients requires prompt surgery, thus genetic testing for Lynch Syndrome is frequently missed, and clinical management may result incorrect.
Baiocchi GL   +9 more
core   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue   +3 more
wiley   +1 more source

Diagnóstico y comportamiento clínico de pacientes con sospecha de síndrome de Lynch sin mutación conocida

open access: yesRevista de Gastroenterología de México, 2018
Resumen: Introducción y objetivos: La sospecha de síndrome de Lynch sin mutación conocida (SSL) se diagnostica cuando existe déficit de expresión de las proteínas reparadoras de ADN pero con estudio genético normal.
L. Adán-Merino   +5 more
doaj   +1 more source

Pre-pregnancy predictors of hypertension in pregnancy among Aboriginal and Torres Strait Islander women in north Queensland, Australia; a prospective cohort study [PDF]

open access: yes, 2013
BACKGROUND Compared to other Australian women, Indigenous women are frequently at greater risk for hypertensive disorders of pregnancy. We examined pre-pregnancy factors that may predict hypertension in pregnancy in a cohort of Aboriginal and Torres ...
Adrian Esterman   +36 more
core   +2 more sources

Predictors of reduced length of stay in minimally invasive colectomy, a 20‐year study

open access: yesSurgical Practice, EarlyView.
Abstract Purpose Minimally invasive colorectal resection is a common surgical procedure indicated for a variety of malignant and benign conditions. Length of stay (los) is an important metric in the evaluation of surgical care quality and healthcare expenditure.
Elisa Tran   +4 more
wiley   +1 more source

Lynch Syndrome [PDF]

open access: yes, 2020
Andreas V. Hadjinicolaou   +1 more
  +5 more sources

Squamous Cell Carcinoma of the Lung With Microsatellite Instability in a Patient With Lynch Syndrome: A Case Report

open access: yesJTO Clinical and Research Reports
Lynch syndrome is the most common autosomal dominant inherited cancer predisposing syndrome, due to mutations in DNA mismatch repair genes. The key feature of cancers in Lynch syndrome is microsatellite instability and a high risk of developing mainly ...
Emna Haddad, MD   +13 more
doaj   +1 more source

Diagnosis and clinical behavior in patients with Lynch-like syndrome

open access: yesRevista de Gastroenterología de México (English Edition), 2018
Introduction and aims: Lynch-like syndrome is diagnosed when there is an expression deficit in DNA mismatch repair proteins but a normal genetic study. The behavior and management of that pathology are currently a subject of debate. We present herein the
L. Adán-Merino   +5 more
doaj   +1 more source

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