Results 91 to 100 of about 1,289,326 (214)

Low yield of gastroscopy in patients with Lynch syndrome

The Turkish Journal of Gastroenterology, 2017
Background/Aims: Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by germline mutations in mismatch-repair genes.
Polymnia Galiatsatos, Christopher Labos, Marie Jeanjean, Kyle Miller, William D. Foulkes   +4 more
doaj   +1 more source

A Micro-Costing Study of Screening for Lynch Syndrome-Associated Pathogenic Variants in an Unselected Endometrial Cancer Population: Cheap as NGS Chips?

Frontiers in Oncology, 2019
Background: Lynch syndrome is the most common inherited cause of endometrial cancer. Identifying individuals affected by Lynch syndrome enables risk-reducing interventions including colorectal surveillance, and cascade testing of relatives.Methods: We ...
Neil A. J. Ryan, Neil A. J. Ryan, Niall J. Davison, Katherine Payne, Anne Cole, D. Gareth Evans, D. Gareth Evans, D. Gareth Evans, Emma J. Crosbie, Emma J. Crosbie, Emma J. Crosbie   +10 more
doaj   +1 more source

Behavioural Diversity of Fishes: Concepts, Drivers and Its Role in Conservation and Management

Fish and Fisheries, EarlyView.
ABSTRACT Human activity has altered nearly all ecosystems on Earth, contributing to substantial biodiversity loss across taxonomic, genetic and functional dimensions, from the intraspecific to the ecosystem scale. Yet some components of biodiversity remain hidden or underappreciated, including behavioural diversity.
Marie Prchalová, Robert Arlinghaus, Samuel Westrelin, Ivan Jarić, Michael G. Bertram, Josep Alós, Henrik Baktoft, Jack A. Brand, Tomas Brodin, Adolfo Cordero‐Rivera, Carlina Feldmann, Ryo Futamura, Stefan Hont, Pascal Klamser, Cecilie Iden Nilsen, Johann Mourier, Karl Øystein Gjelland, Esben Moland Olsen, Polona Pengal, Rubén Rabaneda‐Bueno, Milan Říha, Theresa Rueger, Holger Schielzeth, Marco Signaroli, Marija Smederevac‐Lalić, Christopher T. Monk   +25 more
wiley   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Misdiagnosed, misunderstood and missing out: Lynch Syndrome, Australia's untold health story [PDF]

, 2017
Rice, Toni, O'Neill, Sharron ; https://orcid.org/, Morris, Susan, Fairbank, Beth, Raets, Eve   +4 more
core   +2 more sources

MSH6 germline mutations leading to Lynch syndrome-associated cholangiocarcinoma: a case report

Frontiers in Oncology
Lynch syndrome, a hereditary cancer susceptibility syndrome, arises from pathogenic mutations in mismatch repair genes. This syndrome is strongly linked to colorectal and endometrial cancers, as well as an elevated risk for other cancers such as gastric,
Zheng Zhang, Subo Ma, Shixing Li, Zhengfu Chen, Runda Song, Zhanpeng Wang   +5 more
doaj   +1 more source

Avoidance habit learning after recovery from anorexia nervosa: An fMRI study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Anorexia Nervosa (AN) has been linked to altered self‐regulatory control processes and maladaptive habitual avoidance behavior. Both goal‐directed and habit systems may be relevant to AN, in which restrictive eating behavior can appear highly deliberate and increasingly automatic over time.
Clara M. Breier, Julius Hennig, Joseph A. King, Daniel Geisler, Arne Doose, Ilka Boehm, Maria Seidel, Tung Anh Nguyen, Katharina Zwosta, Veit Roessner, Uta Wolfensteller, Hannes Ruge, Stefan Ehrlich   +12 more
wiley   +1 more source

Expert‐Based Prioritization of Control Measures for Salmonid Rickettsial Septicemia in Chilean Salmon Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Piscirickettsiosis (SRS) remains the main infectious disease affecting salmon aquaculture in Chile. This study evaluated expert perceptions of the effectiveness of SRS control measures and the level of agreement among industry professionals.
Patricio Bustos, Benjamín Diethelm‐Varela, Andrés Riofrio, Marcos Mancilla, Fernando O. Mardones   +4 more
wiley   +1 more source

Self‐Directed Mikoto Simulator Training for Colonoscopy in Gastroenterology Trainees: An International Multicenter Randomized Trial

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Objectives Simulation‐based colonoscopy training may support early acquisition of insertion skills, but its clinical effect remains uncertain. We evaluated whether a self‐directed curriculum using the mikoto colonoscopy simulator improved insertion performance in gastroenterology trainees.
Daisuke Yamaguchi, Ryo Shimoda, Masashi Fujii, Tomohiko Richard Ohya, Han‐Mo Chiu, Naoyuki Tominaga, Hidenori Hidaka, Hiroharu Kawakubo, Yosuke Minoda, Kosuke Maehara, Hiroko Fukuda, Takuma Okamura, Kiwamu Tanaka, Masakuni Kobayashi, Tetsuhito Muranaka, Shuichi Miyamoto, Mitsuru Esaki, Ayako Takamori, Yuichiro Ikebuchi, Taro Akashi, Naoyuki Yamaguchi, Masaru Ueki, Hajime Isomoto, Motohiro Esaki   +23 more
wiley   +1 more source

A Lynch Syndrome Family With Germline <i>MLH1</i> c.931A>G Showing Preserved Tumor MMR Immunostaining but MSI-H Status: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Lynch syndrome screening may be complicated by discordant tumor testing results. We report a family carrying the germline MLH1 c.931A>G (p.Lys311Glu) variant in which both the proband and his father had colorectal tumors with retained mismatch repair protein expression by immunohistochemistry but microsatellite instability‐high status on tumor
Cai J, Li Z, Han T, Guo Y, Du Y, Liu D, Liu X.   +6 more
europepmc   +2 more sources