Results 91 to 100 of about 31,569 (215)
Translating Genomic Competencies Into Cancer Nursing Practice: A Scoping Review
Journal of Clinical Nursing, EarlyView.ABSTRACT Genomics‐informed cancer care is central to precision oncology; however, integrating genomic competencies into routine practice remains challenging. Despite the development of competency frameworks, limited clarity exists regarding how these competencies are operationalised within oncology settings. Aim To synthesise and critically examine how
Libby Rea Brownlee +5 more
wiley +1 more source
Journal of Clinical Nursing, EarlyView.ABSTRACT Aims To explore the experiences and challenges associated with genetic testing decisions among untested individuals from hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) families. Design Qualitative descriptive study. Methods Semi‐structured telephone interviews were conducted between 2022 and 2024 with 56 untested at‐risk ...
Ronit G. Tsemach +8 more
wiley +1 more source
The roads most traveled: genetic convergence in plant repeated evolution
New Phytologist, EarlyView.Observation of a genotype–phenotype association in a focal lineage (magnifying lens) provides a starting point for predicting homolog reuse during repeated trait evolution. This review suggests that the likelihood that mutations in homologous genes contribute to similar phenotypes in other lineages depends on both mutational effect stability (MES) and ...
James W. Satterlee
wiley +1 more source
DEN Open, Volume 7, Issue 1, April 2027.ABSTRACT Background and Aim Emerging endoscopic techniques are expanding opportunities for minimally invasive therapy in early colorectal cancers (CRCs). Data regarding the clinicopathological features and outcomes of colon versus rectal cancers in Tis, T1, and T2 stages remain limited.
Shunto Iwasaki +17 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 8, Page 1873-1883, 15 October 2026.ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...
Christine Worthington +105 more
wiley +1 more source
Prevalence of Helicobacter pylori Exposure and Risk Factors Among BRCA1 and BRCA2 Carriers
International Journal of Cancer, Volume 159, Issue 7, Page 1663-1668, 1 October 2026.BRCA1 and BRCA2 pathogenic germline variant (PGV) carriers may be at increased risk of gastric cancer (GC), especially in the case of prior or active Helicobacter pylori (Hp) infection. The extent to which Hp influences BRCA1 and BRCA2‐associated GC remains uncertain. Here, the authors evaluated plasma samples from a U.S. cohort of BRCA1, BRCA2, PALB2,
Kole H. Buckley +12 more
wiley +1 more source
Learning Health Systems, Volume 10, Issue 4, October 2026.ABSTRACT Introduction The UK National Institute for Health and Care Excellence (NICE) produce guidelines that provide evidence‐based recommendations to support clinical care across England and Wales, but remain available in unstructured natural language form.
Ashvin Gupta +3 more
wiley +1 more source
Mismatch repair genes in Lynch syndrome: a review
São Paulo Medical JournalLynch syndrome represents 1-7% of all cases of colorectal cancer and is an autosomal-dominant inherited cancer predisposition syndrome caused by germline mutations in deoxyribonucleic acid (DNA) mismatch repair genes.
Felipe Cavalcanti Carneiro da Silva +4 more
doaj +1 more source
The History of Lynch Syndrome [PDF]
Familial Cancer, 2013 C Richard, Boland, Henry T, Lynch
openaire +2 more sources