Results 91 to 100 of about 1,085 (178)

Freeze-drying of filamentous fungi and yeasts [PDF]

, 2011
The aim of this thesis was to optimize the freeze-drying protocol for fungi in general and for those genera that do not survive this preservation method, in particular.
Tan, C.S.
core   +1 more source

Combination of trehalose and inulin efficacy as lyoprotectant for the preservation of human monocytic cell line

Cryobiology
Traditional cell cryopreservation is expensive and logistically complex, and it necessitates a constant cold chain [44,57]. Lyophilization presents an alluring substitute, so long as the right lyoprotectants are applied to preserve cell integrity [23,40,44,52].
Alina Meiss, Gretel Chometon, Jonas Greinwald, Luis Gautzsch, Kilian Hennes   +4 more
openaire   +2 more sources

Consistent Intraocular Pressure Reduction by Solid Drug Nanoparticles in Fixed Combinations for Glaucoma Therapy

Advanced Science
Efficient topical drug delivery remains a significant challenge in glaucoma management. Although nanoparticle formulations offer considerable promise, their complex preparation processes, co‐delivery issues, and batch consistency have hindered their ...
Da Huang, Pedro Norat, Lin Qi, Anna Chernatynskaya, James D. Cole, Vimalin Jeyalatha Mani, Lei Xu, Xiaorong Liu, Hu Yang   +8 more
doaj   +1 more source

Stability insights into synthetic biology enabled biosensors: A case study with SARS-CoV2 toehold-based colorimetric sensor

Sensing and Bio-Sensing Research
Improving medical and environmental diagnostics has become a pressing need. Synthetic biologists are steering biomolecular engineering efforts toward this objective, promising novel, cost-effective diagnostic solutions.
Swetha Mariam Stanley, Harvinder Khera
doaj   +1 more source

Physical Evaluations of Freeze-Dried Ca-Alginate Microspheres Containing Ovalbumin Using Different Lyoprotectants [PDF]

, 2015
The main objective of the research was to investigate physical evaluations of freeze-dried ovalbumin loaded-Ca alginate microspheres. This research used alginate, CaCl2 and lyoprotectants (maltodextrin, lactose or sucrose).
Melani Hariyadi Dewi, Destia, Wardhani, Tutiek, Purwanti, Sisilia, Ermawahyuningtyas   +3 more
core  

Investigating the impact of trehalose crystallization on protein aggregation in lyophilized formulations

AAPS Open
Trehalose is a commonly used lyoprotectant for stabilizing proteins in lyophilized formulations. Its physical state plays a critical role in maintaining both the physical and chemical stability of proteins. In this study, three types of protein/trehalose
Rachana Sapkota, Isabella Perez Mejia, Cole W. Tower, Nicholas J. Huls, Harshil K. Renawala, Eric J. Munson   +5 more
doaj   +1 more source

Physical Characteristics of Liposomal Formulation dispersed in HPMC Matrix and Freeze-Dried using Maltodextrin and Mannitol as Lyoprotectan [PDF]

, 2017
Background: The present study aims to design formulation of liposomes that are well-preserved during freeze-drying. The combination of Hydroxy Propyl Methyl Cellulose (HPMC) as dispersion matrix and lyoprotectants; maltodextrin or mannitol, was ...
Raditya Weka Nugraheni, Helmy Yusuf, Dwi Setyawan   +2 more
core   +1 more source

PENGARUH KADAR MALTODEKSTRIN (0%, 5%, 10%) TERHADAP KARAKTERISTIK MIKROSFER PROBIOTIK Lactobacillus acidophilus FNCC-0051 DENGAN MATRIKS NATRIUM ALGINAT 2% [PDF]

, 2019
The aim of this research was to investigate the role of maltodextrine as lyoprotectant to the characteristic of Lactobacillus acidophilus probiotic microsphere with alginate (2%) as its polymer matrix.
NI MADE PUJASTUTI RAHAYU, 051511133187
core  

Application of Lyophilized Gene-Delivery Formulations to Dental Implant Surfaces: Non-Cariogenic Lyoprotectant Preserves Transfection Activity of Polyplexes Long-Term. [PDF]

J Pharm Sci, 2023
Malkawi WI, Laird NZ, Phruttiwanichakun P, Mohamed E, Elangovan S, Salem AK.   +5 more
europepmc   +1 more source

Development and validation of the 6-dye lyophilized fluorescent multiplex PCR system. [PDF]

PLoS One
Cui Y, Zhang Z, Yu H, Ji M, Jia L, Song W, Wang J, Shang L, Bai X.   +8 more
europepmc   +1 more source