Results 71 to 80 of about 1,085 (178)

Hyperspectral Imaging Techniques for Lyophilization: Advances in Data‐Driven Modeling Strategies and Applications

Advanced Science, Volume 12, Issue 33, September 4, 2025.
Lyophilization is a key process used in the production of biotherapeutic products. This article reviews and discusses the application of HSI on lyophilization, and the strategies that use the resulting data to build models. It is intended to provide guidance and insights for non‐specialist researchers and engineers into leveraging HSI and the data ...
Huiwen Yu, Prakitr Srisuma, Cedric Devos, Jie Wang, Allan S. Myerson, Richard D. Braatz   +5 more
wiley   +1 more source

Preparation of Glycyrrhetinic Acid Liposomes Using Lyophilization Monophase Solution Method: Preformulation, Optimization, and In Vitro Evaluation

Nanoscale Research Letters, 2018
In this study, glycyrrhetinic acid (GA) liposomes were successfully prepared using lyophilization monophase solution method. Preformulation studies comprised evaluation of solubility of soybean phosphatidylcholine (SPC), cholesterol, and GA in tert-butyl
Tingting Liu, Wenquan Zhu, Cuiyan Han, Xiaoyu Sui, Chang Liu, Xiaoxing Ma, Yan Dong   +6 more
doaj   +1 more source

Liposomal Encapsulation in Food Systems: A Review of Formulation, Processing, and Applications

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Liposomal microencapsulation stands as a promising technique for the food industry, offering versatile solutions to protect, deliver, and enhance the functionality of bioactive compounds, enzymes, and other food ingredients. This review has highlighted the fundamental aspects of liposomes, including their structure, properties, and formulation methods,
Muhammad Abdul Rahim, Hamdy A. Zahran, Hafiza Madiha Jaffar, Saadia Ambreen, Mohamed Fawzy Ramadan, Fahad Al‐Asmari, Roberto Castro‐Muñoz, Eliasse Zongo   +7 more
wiley   +1 more source

Pengaruh Lioprotektant Terhadap Karakteristik Nanopartikel Artesunat-Kitosan Yang Dibuat Dengan Gelasi Ionik-Pengeringan Beku

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2018
Latar belakang: Nanopartikel merupakan partikel dengan rentang ukuran diameter antara 1 - 1000 nm. Nanopartikel Artesunat-Khitosan diformulasikan menjadi nanopartikel menggunakan metode gelasi ionik-pengering beku ditujukan untuk melindungi bahan obat ...
Abhimata Paramanandana, Retno Sari, Pawahid Pawahid, Eryka A. Novarinandha, Widji Soeratri   +4 more
doaj   +1 more source

Spectral fingerprinting to evaluate effects of storage conditions on biomolecular structure of filter-dried saliva samples and recovered DNA

Scientific Reports, 2020
Saliva has been widely recognized as a non-invasive, painless and easy-to-collect bodily fluid, which contains biomarkers that can be used for diagnosis of both oral and systemic diseases.
Raffaele Brogna, Harriëtte Oldenhof, Harald Sieme, Willem F. Wolkers   +3 more
doaj   +1 more source

Polyethylene Glycol Nanofiller for Robust Lyophilization of Graphically Encoded Hydrogel Microparticles

Small, Volume 21, Issue 32, August 14, 2025.
The polyethylene glycol (PEG) nanofiller exerts a superior stabilization effect on the geometries and porous structures of the graphically encoded hydrogel microparticles in a lyophilization process. The as‐lyophilized microparticles can exert robust immunoassay performances (limit of detection: 6.48 pg mL−1) after thermal aging treatment, which ...
Wookyoung Jang, Ji Won Byun, Jun Hee Choi, Bolam Kim, Ki Wan Bong   +4 more
wiley   +1 more source

Design and Validation of Hybrid Polymer‐Lipid Nanoparticles as Novel Transfection Vectors for MicroRNA Delivery to Human Cardiac Fibroblasts

Advanced Healthcare Materials, Volume 14, Issue 18, July 15, 2025.
Hybrid NPs are developed as efficient, scalable nanocarriers for in vitro microRNA delivery, ensuring high loading efficiency, controlled release, physiological and long‐term storage stability. They outperform commercial lipid‐based reagents in terms of transfection efficiency and biocompatibility.
Letizia Nicoletti, Camilla Paoletti, Martina Coletto, Elena Marcello, Giovanni Paolo Stola, Francesca Cossetta, Francesco Schiavone, Ilaria Andreana, Barbara Stella, Silvia Arpicco, Clara Mattu, Valeria Chiono   +11 more
wiley   +1 more source

PENGARUH RASIO OBAT DAN POLIMER TERHADAP KARAKTERISTIK MIKROSFER CIPROFLOXACIN DENGAN MATRIKS ALGINAT-KARAGENAN [PDF]

, 2019
alginate concentrations on the characteristic of microspheres. Ciprofloxacin HCl- alginate-carrageenan microspheres were made by ionotropic gelation method using aerosolization technique with rati of drug and polymer 1 :0.83(F1) ; 1 :1.25(F2) ; and 1
AKBAR TRINANDA FIRMAN, 051511133228
core   +1 more source

Preparation and Optimization of 10-Hydroxycamptothecin Nanocolloidal Particles Using Antisolvent Method Combined with High Pressure Homogenization

Journal of Chemistry, 2017
The aim of this study was to prepare 10-hydroxycamptothecin nanocolloidal particles (HCPTNPs) to increase the solubility of drugs, reduce the toxicity, improve the stability of the drug, and so forth. HCPTNPs was prepared by antisolvent precipitation (AP)
Bolin Lian, Yong Li, Xiuhua Zhao, Yuangang Zu, Ying Wang, Yin Zhang, Yuanyuan Li   +6 more
doaj   +1 more source

Stabilization of gene delivery systems by freeze-drying

, 1997
Freeze-drying of three different forms of gene delivery systems was performed using a controlled two-step drying process and 10% sucrose as lyoprotectant.
Talsma, Herre, Kursa, Malgorzata, Cherng, Jong-Yuh, Wim E Hennink, Manfred Ogris, Wagner, Ernst, Ernst Wagner, Cotten, Matt, Lehrmann, Heike, Ogris, Manfred, Jong-Yuh Cherng, Hennink, Wim E., Malgorzata Kursa, Matt Cotten, Heike Lehrmann, Herre Talsma   +15 more
core   +1 more source