Results 61 to 70 of about 1,064 (143)

The mechanisms of Wickhamomyces anomalus in control of postharvest black spot disease in tomatoes and the preparation of its biocontrol solid products

Agriculture Communications
Postharvest black spot of tomato causes considerable economic losses to the tomato industry. Biological control presents a sustainable and efficient alternative. This study investigated the biocontrol mechanism of Wickhamomyces anomalus and optimized its
Xi Zhang, Marui Zhu, Dhanasekaran Solairaj, Kaili Wang, Qiya Yang, Hongyin Zhang   +5 more
doaj   +1 more source

Transcatheter Intra‐Arterial Delivery of a Platelet‐Derived Extracellular Vesicle‐Enriched Preparation for Attenuating Skeletal Muscle Ischaemia‐Reperfusion Injury in a Rodent Forelimb Model

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) are non‐replicating, lipid membrane‐bound nanoparticles released by most eukaryotic cells into the extracellular space. When derived from platelets, a subset of EVs can exhibit remarkable anti‐inflammatory and antioxidant properties, making them attractive candidates to attenuate sterile inflammatory states such as
Omar A. Selim, Aida Sarcon, Atta Behfar, Chunfeng Zhao, Steven L. Moran   +4 more
wiley   +1 more source

Biophysical evaluation of aminoclay as an effective protectant for protein stabilization during freeze-drying and storage

International Journal of Nanomedicine, 2016
Jae Geun Song, Sang Hoon Lee, Hyo-Kyung Han College of Pharmacy, Dongguk University, Goyang, South Korea Abstract: This study aimed to evaluate aminoclay (3-aminopropyl-functionalized magnesium phyllosilicate) as an effective protectant for the ...
Song JG, Lee SH, Han HK
doaj  

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

Small, Volume 22, Issue 16, 17 March 2026.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen, Luke van der Koog, Robin A.B. Elferink, Karim Rafie, Anika Nagelkerke, Reinoud Gosens, Henderik W. Frijlink, Wouter L.J. Hinrichs   +7 more
wiley   +1 more source

Drug Product Development of Lipid Nanoparticle‐Based mRNA Therapeutics and Vaccines

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.
Overview of the development path from an mRNA–lipid nanoparticle (LNP) concept to a licensed drug product, covering LNP design, manufacturing process development, formulation, and analytical characterization. ABSTRACT Lipid nanoparticles (LNP) are currently the most relevant non‐viral delivery systems for mRNA and occasionally for smaller nucleic acids
Gideon Kersten, Eleonora Cerasoli, Bruce Kerwin, Olivia M. Merkel, Andrea Hawe   +4 more
wiley   +1 more source

Diagram illustrating the surface tension based lyoprocessing technique.

, 2018
A) The substrate is immersed into a trehalose based lyoprotectant solution (indicated as the dotted region). B) The substrate is withdrawn in an inert environment over a stream of Nitrogen gas at a prescribed drawing rate, creating a desiccated film.
Lukas Underwood (4225888), Oleg Zikanov (4911532), Jason Solocinski (4225891), Quinn A. Osgood (4911529), Eric Rosiek (4911526), Nilay Chakraborty (343475)   +5 more
core   +1 more source

Nanomedicine Strategies Against Biofilm‐Associated Infections: Advances, Challenges, and Translational Barriers

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah, Munthar Kadhim‐Abosaoda, Hayjaa Mohaisen‐Mousa, S. Renuka Jyothi, Priya Priyadarshini‐Nayak, J. Bethanney Janney, Gurjant Singh, Ashish Singh‐Chauhan, Manoj Kumar‐Mishra   +8 more
wiley   +1 more source

Characteristics, Release, and Stability (Kinetics and Shelf-life) of Ciprofloxacin HCl-Alginate-Carrageenan Microspheres: Effects of Drug Concentration and Type of Lyoprotectant

Science and Technology Indonesia
Tuberculosis, an infectious disease caused by the Mycobacterium tuberculosis bacteria, is one of the main causes of death worldwide. Alternative treatments are necessary due to the rising prevalence of medication resistance in Mycobacterium tuberculosis.
Amiruddin, Mahardian Rahmadi, Dewi Melani Hariyadi   +2 more
doaj   +1 more source

Freezing the Moment: Monitoring Freezing Processes Under MAS Conditions

Magnetic Resonance in Chemistry, Volume 64, Issue 2, Page 193-206, February 2026.
NMR spectroscopy under magic angle spinning conditions allows studying the freezing of aqueous solutions and gel‐like systems down to subfreezing temperatures. We thoroughly monitored the freezing process of various aqueous systems containing multiple NMR‐active nuclei (1H, 11B, 13C, 23Na, and 79Br). We focus on prerequisites, problems, and limitations
Sebastian Scheidel, Elena Behr, Ann‐Christin Pöppler   +2 more
wiley   +1 more source

Injectable Chitosan‐Platelet‐Rich Plasma Hybrid Biomaterial Improves Skin Wound Healing in Diabetic Rats

Advanced Therapeutics, Volume 9, Issue 1, January 2026.
A biomaterial combining fresh platelet‐rich plasma with freeze‐dried chitosan (CS‐PRP) enhances diabetic skin wound healing in rats. CS‐PRP accelerates closure over the course of a month, improves healing tissue architecture and collagen remodeling, and sustains vascularization.
Laura Ahunon, Anik Chevrier, Léo‐Paul Tricou, Aurélie Huppé, Julie Fradette, Marc Lavertu   +5 more
wiley   +1 more source