Results 41 to 50 of about 1,085 (178)

Preliminary formulation development of silicone elastomer vaginal rings for sustained release of metronidazole, sucrose and lactobacillus

open access: yes, 2021
Background: Bacterial vaginosis (BV) is a common dysbiosis of the human vagina in which commensal vaginal lactobacilli are displaced by mixed pathogenic bacterial populations.
Kett, Victoria; id_orcid   +3 more
core   +4 more sources

Natural Product‐Derived Vesicles in Nanotherapeutics

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Standardized freeze-dried FMT: is the ideal protectant out there?

open access: yesFrontiers in Microbiology
BackgroundFecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infections. Freeze-drying offers a next-generation, more practical, and aesthetically acceptable FMT formulation that could facilitate ...
Alix Pourrat   +7 more
doaj   +1 more source

Vaginal formulations containing prebiotics and probiotics for treatment of bacterial vaginosis

open access: yesBritish Journal of Pharmacy, 2022
Bacterial vaginosis (BV) is a common dysbiosis of the human vagina in which commensal vaginal lactobacilli are displaced by mixed pathogenic bacterial populations. Current treatments by antibiotics result in short- term cure but often lead to recurrence.
Caixuan Wang   +3 more
doaj   +1 more source

Influence of type and proportion of lyoprotectants on lyophilized ginsenoside Rg3 liposomes

open access: yesJournal of Pharmacy and Pharmacology, 2016
Abstract Objectives To improve stability and shelf life, lyophilized formulations of 20(R)-Ginsenoside Rg3 liposomes (G-Rg3-Ls) were prepared. Methods Glucose, trehalose, sucrose, maltose, lactose, mannitol, inositol, hydroxypropyl-β ...
Jianying, Li   +8 more
openaire   +2 more sources

Regenerative Microbiology: Harnessing Bacterial Antagonism and Spatiotemporal Signaling for Diabetic Wound Repair

open access: yesSmart Medicine, Volume 5, Issue 4, August 2026.
This review introduces “Regenerative Microbiology,” a framework that uses bacterial antagonism and phage therapy to address diabetic wound dysbiosis. By activating the p40/EGFR/PI3K axis and providing a vascular‐stratified precision roadmap, this approach shifts the paradigm from antimicrobial suppression to intelligent, microbe‐driven tissue ...
Sabri Saeed Sanabani
wiley   +1 more source

Assessing Storage of Stability and Mercury Reduction of Freeze-Dried Pseudomonas putida within Different Types of Lyoprotectant

open access: yes, 2016
Pseudomonas putida is a potential strain in biological treatment to remove mercury contained in the effluent of petrochemical industry due to its mercury reductase enzyme that able to reduce ionic mercury to elementary mercury. Freeze-dried P.
Y. Nuratri   +4 more
core   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, Volume 38, Issue 33, 12 June 2026.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Potential of Covalent Organic Framework in Pharmacy and Biomedicine: Influence of Structure on Properties and Applications

open access: yesChemMedChem, Volume 21, Issue 9, 14 May 2026.
From modular COF design to biomedical translation, this Review maps how linkage chemistry, topology, pore environment, and particle engineering govern bioperformance, therapeutic and diagnostic function, safety, and clinical readiness. Covalent organic frameworks (COFs) are a versatile class of crystalline porous materials with growing potential in ...
Julia Kolodziejczyk   +1 more
wiley   +1 more source

Stabilization of eye drops containing autologous serum and recombinant human epidermal growth factor for dry eye syndrome

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2020
Human epidermal growth factor (hEGF) and autologous serum are considered safer and more effective in treating dry eye syndrome. However, suitable formulas and preparation methods are needed to obtain eye drop containing autologous serum and hEGF, which ...
Sriwidodo Sriwidodo   +5 more
doaj   +1 more source

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