In order to prepare a better direct vat set for malolactic fermentation (MLF) in high ethanol and low pH wines, the high-ethanol- and low-temperature-tolerant strain Lentilactobacillus hilgardii Q19, which was isolated from the eastern foothill of the ...
Ling Wang, Gang Huang, Wen Ma, Gang Jin
doaj +2 more sources
Preparation, characterization and in vitro evaluation of atorvastatin nanosuspensions. [PDF]
Poorly water-soluble drugs present a significant challenge for pharmaceutical development, particularly affecting the pharmacokinetics of orally administered drugs due to their poor dissolution.
Yaman Ahmad Akour +4 more
doaj +2 more sources
Impact of nanocarrier aggregation on EPR-mediated tumor targeting [PDF]
The aim of this study was to investigate the influence of excipients on retaining the particle size of methotrexate (MTX) loaded chitosan nanocarriers (CsNP) during lyophilization, which relates to the ability to enlarge the particle size and target ...
S. P. Surya Teja +13 more
doaj +2 more sources
Storage Stabilisation of Albumin-Loaded Chitosan Nanoparticles by Lyoprotectants [PDF]
Purpose: To investigate the effect of lyoprotectants on the physical and storage stability of lyophilised bovine serum albumin-loaded chitosan/dextran sulphate (BSA-loaded CS/DS) nanoparticles.Methods: BSA-loaded CS/DS nanoparticles were prepared by ionic-gelation technique.
Katas, Haliza +2 more
openaire +4 more sources
Protective Effects Proanthocyanidin Nanoliposome Freeze-Dried Powder on Oxidative Injury in a p31-43 Induced Celiac Disease Cell Model. [PDF]
Proanthocyanidin nanoliposome freeze‐dried powder (PCNL‐FD) with 4% trehalose maintained excellent stability and encapsulation efficiency, demonstrating enhanced antioxidant activity compared to free proanthocyanidins. In a celiac disease cell model, PCNL‐FD significantly reduced oxidative stress by decreasing ROS and MDA while increasing GSH and ...
Ning Z +9 more
europepmc +2 more sources
Limosilactobacillus reuteri DSM 17938 Produce Bioactive Components during Formulation in Sucrose [PDF]
Improved efficacy of probiotics can be achieved by using different strategies, including the optimization of production parameters. The impact of fermentation parameters on bacterial physiology is a frequently investigated topic, but what happens during ...
Ludwig Ermann Lundberg +6 more
doaj +2 more sources
Development of Robust Freeze-Drying Process for Long-Term Stability of rVSV-SARS-CoV-2 Vaccine [PDF]
The thermostability of vaccines, particularly enveloped viral vectored vaccines, remains a challenge to their delivery wherever needed. The freeze-drying of viral vectored vaccines is a promising approach but remains challenging due to the water removal ...
MD Faizul Hussain Khan +3 more
doaj +2 more sources
Fabrication of Ciprofloxacin-Loaded Sodium Alginate Nanobeads Coated with Thiol-Anchored Chitosan Using B-390 Encapsulator Following Optimization by DoE [PDF]
Most infectious diseases of the gastrointestinal tract can easily be treated by exploiting the already available antibiotics with the change in administration approach and delivery system.
Mahwash Mukhtar +8 more
doaj +2 more sources
Background: Bacterial vaginosis (BV) is a disease that widely affects women’s health. More than 50% of all women globally experience vaginitis of varying severity.
Wang, Caixuan +3 more
core +3 more sources
Dextranol: A better lyoprotectant [PDF]
Dextranol, a reduced dextran, prevents damage to stored dry protein samples that unmodified dextran would otherwise cause. Lyoprotectants like the polysaccharide dextran are critical for preserving dried protein samples by forming rigid a glass that protects entrapped protein molecules.
Jones, Bryan Joshua +2 more
openaire +1 more source

