Results 31 to 40 of about 1,064 (143)

Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging

Pharmaceutics, 2018
Nowadays, the freeze-drying of liposome dispersions is still necessary to provide a solid dosage form intended for different routes of administration (i.e., parenteral, oral, nasal and/or pulmonary).
Silvia Franzé, Francesca Selmin, Elena Samaritani, Paola Minghetti, Francesco Cilurzo   +4 more
doaj   +1 more source

Optimizing liposomal drug delivery for surgical precision: The crucial role of sucrose as a lyoprotectant

Asian Journal of Surgery
Yong-Jun Xu, Wei-Dong Lu
exaly   +3 more sources

Poster abstract: Formulation and in vitro tests of silicone elastomer vaginal rings containing lyoprotectant and metronidazole [PDF]

, 2022
Background: Bacterial vaginosis (BV) is a disease that widely affects women’s health. More than 50% of all women globally experience vaginitis of varying severity.
Wang, Caixuan, Kett, Vicky; id_orcid, Gilpin, Deirdre, Malcolm, R. Karl; id_orcid   +3 more
core   +4 more sources

Specific Gaseous Conditions Significantly Improve Lactobacillus casei and Escherichia coli Survival to Freeze Drying and Rehydration

Applied Food Biotechnology, 2020
Background and objective: Presence of oxygen during production and rehydration of freeze-dried starters and probiotics can decrease viability of the bacteria.
Aurore Bodzen, Cyril Iaconelli, Alexandre Charriau, Sebastien Dupont, Laurent Beney, Patrick Gervais   +5 more
doaj   +1 more source

PENGARUH KONSENTRASI LYOPROTECTANT TERHADAP KARAKTERISTIK GLUTATION DENGAN LIPOFILISITAS OPTIMAL DALAM SISTEM MIKROSFER ALGINAT DAN UJI PENETRASI [PDF]

, 2018
The aim of this study was to determine the effect of lyoprotectant concentration on the characteristics of glutathione alginate microspheres. Microspheres were prepared using Na-alginate as polymer and CaCl2 as crosslinking agent using ionotopic gelation
NOVIA MIR ROSYIDATIS SYAROFI, 051411131182
core   +1 more source

Screening and Stability Evaluation of Freeze-Dried Protective Agents for a Live Recombinant Pseudorabies Virus Vaccine

Vaccines
Infection of pigs with the pseudorabies virus (PRV) causes significant economic losses in the pig industry. Immunization with live vaccines is a crucial aspect in the prevention of pseudorabies in swine.
Yan Liu, Suling Zhang, Shuai Wang, Chunhui Zhang, Xiaorui Su, Linghua Guo, Xiaofei Bai, Yuxin Huang, Wenqiang Pang, Feifei Tan, Kegong Tian   +10 more
doaj   +1 more source

Statistical modelling for optimized lyophilization of Lactobacillus acidophilus strains for improved viability and stability using response surface methodology

AMB Express, 2018
The awareness regarding use of probiotics for health benefits has created a huge market worldwide. The use of probiotic cultures and its success in commercial scale is relying on the techniques employed to ensure that the potential cultures with desired ...
Lakshminarayana Turuvekere Sadguruprasad, Madhusudhan Basavaraj   +1 more
doaj   +1 more source

Development of a Lyophilized Off-the-Shelf Mesenchymal Stem Cell-Derived Acellular Therapeutic

Pharmaceutics, 2022
The therapeutic activities elicited by mesenchymal stem cells (MSC) are in part mediated through paracrine action by the release of extracellular vesicles (EV) and secreted proteins.
Julia Driscoll, Irene K. Yan, Tushar Patel   +2 more
doaj   +1 more source

Standardized freeze-dried FMT: is the ideal protectant out there?

Frontiers in Microbiology
BackgroundFecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infections. Freeze-drying offers a next-generation, more practical, and aesthetically acceptable FMT formulation that could facilitate ...
Alix Pourrat, Vinciane Baillieu, Solene Ansel, Maxime Leonardi, Pierre Poiron, Samuel Bellais, Muriel Paul, Biba Nebbad   +7 more
doaj   +1 more source

Self‐Assembled Hybrid Cell‐Enzyme Materials for Gas‐Powered Biocatalysis

Advanced Functional Materials, Volume 36, Issue 82, 12 October 2026.
Integrating living cells with programmable enzyme networks enables hybrid materials that convert gaseous feedstocks into chemical reducing power. These gas‐powered catalytic beads operate as modular, recyclable platforms for adaptive biocatalysis and sustainable synthesis.
Marius Stoeckle, Kersten S. Rabe, Christof M. Niemeyer   +2 more
wiley   +1 more source