Results 31 to 40 of about 1,085 (178)

Preserving the Integrity of Liposomes Prepared by Ethanol Injection upon Freeze-Drying: Insights from Combined Molecular Dynamics Simulations and Experimental Data

open access: yesPharmaceutics, 2020
The freeze-drying of complex formulations, such as liposomes, is challenging, particularly if dispersions contain residual organic solvents. This work aimed to investigate the effects of possible protectants, namely sucrose, trehalose and/or poly(vinyl ...
Silvia Franzè   +5 more
doaj   +1 more source

Lyophilization Preserves the Intrinsic Cardioprotective Activity of Bioinspired Cell-Derived Nanovesicles

open access: yesPharmaceutics, 2021
Recently, bioinspired cell-derived nanovesicles (CDNs) have gained much interest in the field of nanomedicine due to the preservation of biomolecular structure characteristics derived from their parent cells, which impart CDNs with unique properties in ...
Yub Raj Neupane   +10 more
doaj   +1 more source

Assessing storage stability and mercury reduction of freeze-dried pseudomonas putida within different types of lyoprotectant [PDF]

open access: yes, 2015
Pseudomonas putida is a potential strain in biological treatment to remove mercury contained in the effluent of petrochemical industry due to its mercury reductase enzyme that able to reduce ionic mercury to elementary mercury. Freeze-dried P.
Yana, Nuratri
core   +2 more sources

Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging

open access: yesPharmaceutics, 2018
Nowadays, the freeze-drying of liposome dispersions is still necessary to provide a solid dosage form intended for different routes of administration (i.e., parenteral, oral, nasal and/or pulmonary).
Silvia Franzé   +4 more
doaj   +1 more source

PENGARUH KONSENTRASI LYOPROTECTANT TERHADAP KARAKTERISTIK GLUTATION DENGAN LIPOFILISITAS OPTIMAL DALAM SISTEM MIKROSFER ALGINAT DAN UJI PENETRASI [PDF]

open access: yes, 2018
The aim of this study was to determine the effect of lyoprotectant concentration on the characteristics of glutathione alginate microspheres. Microspheres were prepared using Na-alginate as polymer and CaCl2 as crosslinking agent using ionotopic gelation
NOVIA MIR ROSYIDATIS SYAROFI, 051411131182
core   +1 more source

Specific Gaseous Conditions Significantly Improve Lactobacillus casei and Escherichia coli Survival to Freeze Drying and Rehydration

open access: yesApplied Food Biotechnology, 2020
Background and objective: Presence of oxygen during production and rehydration of freeze-dried starters and probiotics can decrease viability of the bacteria.
Aurore Bodzen   +5 more
doaj   +1 more source

Improving survival and storage stability of bacteria recalcitrant to freeze-drying: a coordinated study by European culture collections [PDF]

open access: yes, 2015
The objective of this study is to improve the viability after freeze-drying and during storage of delicate or recalcitrant strains safeguarded at biological resource centers.
De Vos, PaulWE10801000355927F3D7C55C-F0ED-11E1-A9DE-61C894A0A6B4   +14 more
core   +2 more sources

Statistical modelling for optimized lyophilization of Lactobacillus acidophilus strains for improved viability and stability using response surface methodology

open access: yesAMB Express, 2018
The awareness regarding use of probiotics for health benefits has created a huge market worldwide. The use of probiotic cultures and its success in commercial scale is relying on the techniques employed to ensure that the potential cultures with desired ...
Lakshminarayana Turuvekere Sadguruprasad   +1 more
doaj   +1 more source

Screening and Stability Evaluation of Freeze-Dried Protective Agents for a Live Recombinant Pseudorabies Virus Vaccine

open access: yesVaccines
Infection of pigs with the pseudorabies virus (PRV) causes significant economic losses in the pig industry. Immunization with live vaccines is a crucial aspect in the prevention of pseudorabies in swine.
Yan Liu   +10 more
doaj   +1 more source

Development of a Lyophilized Off-the-Shelf Mesenchymal Stem Cell-Derived Acellular Therapeutic

open access: yesPharmaceutics, 2022
The therapeutic activities elicited by mesenchymal stem cells (MSC) are in part mediated through paracrine action by the release of extracellular vesicles (EV) and secreted proteins.
Julia Driscoll   +2 more
doaj   +1 more source

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