Results 51 to 60 of about 1,064 (143)

Potential of Covalent Organic Framework in Pharmacy and Biomedicine: Influence of Structure on Properties and Applications

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
From modular COF design to biomedical translation, this Review maps how linkage chemistry, topology, pore environment, and particle engineering govern bioperformance, therapeutic and diagnostic function, safety, and clinical readiness. Covalent organic frameworks (COFs) are a versatile class of crystalline porous materials with growing potential in ...
Julia Kolodziejczyk, Marta E. Plonska‐Brzezinska   +1 more
wiley   +1 more source

PENGARUH RASIO OBAT DAN POLIMER TERHADAP KARAKTERISTIK MIKROSFER CIPROFLOXACIN DENGAN MATRIKS ALGINAT-KARAGENAN [PDF]

, 2019
alginate concentrations on the characteristic of microspheres. Ciprofloxacin HCl- alginate-carrageenan microspheres were made by ionotropic gelation method using aerosolization technique with rati of drug and polymer 1 :0.83(F1) ; 1 :1.25(F2) ; and 1
AKBAR TRINANDA FIRMAN, 051511133228
core   +1 more source

Impact of Paper Substrates and Storage Conditions on the Stability of Blood Grouping Assays

Advanced Materials Interfaces, Volume 13, Issue 8, 21 April 2026.
Four paper‐based blood grouping assays are constructed from cellulose and nitrocellulose, with vertical and lateral flow formats. The optimal storage conditions are determined based on temperature, antibody storage buffer composition, and antibody dilution.
Laura Marcela Rey Gomez, David William Inglis, Andrew Care, Yuling Wang, Rena Hirani   +4 more
wiley   +1 more source

Stabilization of gene delivery systems by freeze-drying

, 1997
Freeze-drying of three different forms of gene delivery systems was performed using a controlled two-step drying process and 10% sucrose as lyoprotectant.
Talsma, Herre, Kursa, Malgorzata, Cherng, Jong-Yuh, Wim E Hennink, Manfred Ogris, Wagner, Ernst, Ernst Wagner, Cotten, Matt, Lehrmann, Heike, Ogris, Manfred, Jong-Yuh Cherng, Hennink, Wim E., Malgorzata Kursa, Matt Cotten, Heike Lehrmann, Herre Talsma   +15 more
core   +1 more source

Preliminary Research on Freeze-drying Preservation of Human Hepatoma Hep-G2 Cells

Zhileng xuebao, 2017
Freeze-drying is a long-term and effective method for cell preservation. The lyoprotectant can have a significant effect on cell freeze-drying. In this study, different volume concentrations of Me2SO, glycerol, and different mass concentrations ...
Song Ping, Li Weijie, Zhou Xinli, Liu Baolin   +3 more
doaj  

Development and Mechanistic Insights into Lyoprotective Technology for Akkermansia muciniphila Live Biotherapeutic Products

Shipin gongye ke-ji
To explore the optimal combination of lyoprotective agents for effectively enhancing the viability of Akkermansia muciniphila (Akk) and elucidating the underlying mechanisms.
Yuanzhi XU, Hongxiao SUN, Yanwei ZHANG, Ziyan HAN, Qinggang XIE, Xiaoxi XU   +5 more
doaj   +1 more source

Standardization of lyophilization medium for Streptococcus thermophilus subjected to viability escalation on freeze drying

Microbiology Research, 2014
The objective of the present study is to develop a lyophilization medium for Streptococcus thermophilus (NCIM 2904) as the industrial exploitation of this bacterium totally depends upon preservation and lyophilization protocols.
Rohit Sharma, Bhagwan S. Sanodiya, Gulab S. Thakur, Pallavi Jaiswal, Anjana Sharma, Prakash S. Bisen   +5 more
doaj   +1 more source

Effect of Mannitol on Physical Characters of Lyophilized Fast-Disintegrating Tablets [PDF]

Journal of Advanced Pharmacy Research, 2017
Objectives:Fast-disintegrating tablets (FDTs) also known as orally-disintegrating tablets, orodispersible tablets, fast-melting tablets, rapid-melt tablets are a relatively new dosage form.
Noha Abdelgawad, Fathy AbdAlla, Samia Omar   +2 more
doaj   +1 more source

The Impact of Formulation and Freeze Drying on the Properties and Performance of Freeze-Dried Limosilactobacillus reuteri R2LC

Applied Microbiology, 2023
Freeze drying is a commonly used method for preserving probiotic bacteria and live biotherapeutic products. Before drying, the bacterial cells are formulated with a lyoprotectant, and the design of these two process steps are crucial to achieve a high ...
Nisha Tyagi, Zandra Gidlöf, Daniel Tristan Osanlóo, Elizabeth S. Collier, Sandeep Kadekar, Lovisa Ringstad, Anna Millqvist Fureby, Stefan Roos   +7 more
doaj   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, Volume 2, Issue 2, April 2026.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source