Results 51 to 60 of about 1,085 (178)

Impact of Paper Substrates and Storage Conditions on the Stability of Blood Grouping Assays

Advanced Materials Interfaces, Volume 13, Issue 8, 21 April 2026.
Four paper‐based blood grouping assays are constructed from cellulose and nitrocellulose, with vertical and lateral flow formats. The optimal storage conditions are determined based on temperature, antibody storage buffer composition, and antibody dilution.
Laura Marcela Rey Gomez, David William Inglis, Andrew Care, Yuling Wang, Rena Hirani   +4 more
wiley   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, Volume 2, Issue 2, April 2026.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Thermostabilization of indigenous multiplex polymerase chain reaction reagents for detection of enterotoxigenic Staphylococcus aureus

Journal of Microbiology, Immunology and Infection, 2018
Background/Purpose: Among DNA-based techniques, polymerase chain reaction (PCR) is the most widely accepted molecular tool for the detection of pathogens.
Sowmya Nagaraj, Shylaja Ramlal, Joseph Kingston, Harsh Vardhan Batra   +3 more
doaj   +1 more source

Transcatheter Intra‐Arterial Delivery of a Platelet‐Derived Extracellular Vesicle‐Enriched Preparation for Attenuating Skeletal Muscle Ischaemia‐Reperfusion Injury in a Rodent Forelimb Model

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) are non‐replicating, lipid membrane‐bound nanoparticles released by most eukaryotic cells into the extracellular space. When derived from platelets, a subset of EVs can exhibit remarkable anti‐inflammatory and antioxidant properties, making them attractive candidates to attenuate sterile inflammatory states such as
Omar A. Selim, Aida Sarcon, Atta Behfar, Chunfeng Zhao, Steven L. Moran   +4 more
wiley   +1 more source

Development and Mechanistic Insights into Lyoprotective Technology for Akkermansia muciniphila Live Biotherapeutic Products

Shipin gongye ke-ji
To explore the optimal combination of lyoprotective agents for effectively enhancing the viability of Akkermansia muciniphila (Akk) and elucidating the underlying mechanisms.
Yuanzhi XU, Hongxiao SUN, Yanwei ZHANG, Ziyan HAN, Qinggang XIE, Xiaoxi XU   +5 more
doaj   +1 more source

Standardization of lyophilization medium for Streptococcus thermophilus subjected to viability escalation on freeze drying

Microbiology Research, 2014
The objective of the present study is to develop a lyophilization medium for Streptococcus thermophilus (NCIM 2904) as the industrial exploitation of this bacterium totally depends upon preservation and lyophilization protocols.
Rohit Sharma, Bhagwan S. Sanodiya, Gulab S. Thakur, Pallavi Jaiswal, Anjana Sharma, Prakash S. Bisen   +5 more
doaj   +1 more source

Effect of Mannitol on Physical Characters of Lyophilized Fast-Disintegrating Tablets [PDF]

Journal of Advanced Pharmacy Research, 2017
Objectives:Fast-disintegrating tablets (FDTs) also known as orally-disintegrating tablets, orodispersible tablets, fast-melting tablets, rapid-melt tablets are a relatively new dosage form.
Noha Abdelgawad, Fathy AbdAlla, Samia Omar   +2 more
doaj   +1 more source

The Impact of Formulation and Freeze Drying on the Properties and Performance of Freeze-Dried Limosilactobacillus reuteri R2LC

Applied Microbiology, 2023
Freeze drying is a commonly used method for preserving probiotic bacteria and live biotherapeutic products. Before drying, the bacterial cells are formulated with a lyoprotectant, and the design of these two process steps are crucial to achieve a high ...
Nisha Tyagi, Zandra Gidlöf, Daniel Tristan Osanlóo, Elizabeth S. Collier, Sandeep Kadekar, Lovisa Ringstad, Anna Millqvist Fureby, Stefan Roos   +7 more
doaj   +1 more source

Biophysical evaluation of aminoclay as an effective protectant for protein stabilization during freeze-drying and storage

International Journal of Nanomedicine, 2016
Jae Geun Song, Sang Hoon Lee, Hyo-Kyung Han College of Pharmacy, Dongguk University, Goyang, South Korea Abstract: This study aimed to evaluate aminoclay (3-aminopropyl-functionalized magnesium phyllosilicate) as an effective protectant for the ...
Song JG, Lee SH, Han HK
doaj  

The mechanisms of Wickhamomyces anomalus in control of postharvest black spot disease in tomatoes and the preparation of its biocontrol solid products

Agriculture Communications
Postharvest black spot of tomato causes considerable economic losses to the tomato industry. Biological control presents a sustainable and efficient alternative. This study investigated the biocontrol mechanism of Wickhamomyces anomalus and optimized its
Xi Zhang, Marui Zhu, Dhanasekaran Solairaj, Kaili Wang, Qiya Yang, Hongyin Zhang   +5 more
doaj   +1 more source