Physical Characteristics of Liposomal Formulation dispersed in HPMC Matrix and Freeze-Dried using Maltodextrin and Mannitol as Lyoprotectan [PDF]
, 2017 Background: The present study aims to design formulation of liposomes that are well-preserved during freeze-drying. The combination of Hydroxy Propyl Methyl Cellulose (HPMC) as dispersion matrix and lyoprotectants; maltodextrin or mannitol, was ...
Raditya Weka Nugraheni +2 more
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Protective Effect of Saccharides on Freeze-Dried Liposomes Encapsulating Drugs
Frontiers in Bioengineering and Biotechnology, 2019 The production of freeze-dried liposomes encapsulating drugs is considered a key challenge since the drugs are prone to leakage. The aim of this work was to study the effect of different saccharides on preserving the stability and drug retention capacity
Diana Guimarães +4 more
doaj +1 more source
Live Biotherapeutics : importance of formulation and lyophilization parametersand an example of a clinical application [PDF]
, 2023 In recent years, probiotics have expanded from their traditional classification as “health promoting food” to the development of live biotherapeutic products (LBP).
Tyagi, Nisha
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Shipin gongye ke-jiIn this paper, 21 strains of Bifidobacteria were isolated and identified from healthy breast milk samples, and the strain with the best activity was selected by spleen lymphocyte proliferation assay, drug sensitivity, haemolysis, bacteriostatic activity,
Haoran SONG +8 more
doaj +1 more source
Microencapsulation of probiotic strain Lactobacillus fermentum D12 after cultivation with addition of different prebiotics [PDF]
, 2018 Tema ovog rada je mikroinkapsulacija probiotičkog soja Lactobacillus fermentum D12 u alginatu uz dodatak prebiotika inulina i fruktooligosaharida, te liofilizacija mikroinkapsuliranih stanica uz dodatak obranog mlijeka kao lioprotektora. Cilj rada bio je
Ursić, Tino
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Advanced ScienceEfficient topical drug delivery remains a significant challenge in glaucoma management. Although nanoparticle formulations offer considerable promise, their complex preparation processes, co‐delivery issues, and batch consistency have hindered their ...
Da Huang +8 more
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Sensing and Bio-Sensing ResearchImproving medical and environmental diagnostics has become a pressing need. Synthetic biologists are steering biomolecular engineering efforts toward this objective, promising novel, cost-effective diagnostic solutions.
Swetha Mariam Stanley, Harvinder Khera
doaj +1 more source
Physical Evaluations of Freeze-Dried Ca-Alginate Microspheres Containing Ovalbumin Using Different Lyoprotectants [PDF]
, 2015 The main objective of the research was to investigate physical evaluations of freeze-dried ovalbumin loaded-Ca alginate microspheres. This research used alginate, CaCl2 and lyoprotectants (maltodextrin, lactose or sucrose).
Melani Hariyadi Dewi +3 more
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AAPS OpenTrehalose is a commonly used lyoprotectant for stabilizing proteins in lyophilized formulations. Its physical state plays a critical role in maintaining both the physical and chemical stability of proteins. In this study, three types of protein/trehalose
Rachana Sapkota +5 more
doaj +1 more source
Application of Lyophilized Gene-Delivery Formulations to Dental Implant Surfaces: Non-Cariogenic Lyoprotectant Preserves Transfection Activity of Polyplexes Long-Term. [PDF]
J Pharm Sci, 2023 Malkawi WI +5 more
europepmc +1 more source