Results 1 to 10 of about 870,020 (286)

KLHL12 promotes non-lysine ubiquitination of the dopamine receptors D-4.2 and D-4.4, but not of the ADHD-associated D-4.7 variant [PDF]

, 2015
Dopamine D-4 Receptor Polymorphism : The dopamine D-4 receptor has an important polymorphism in its third intracellular loop that is intensively studied and has been associated with several abnormal conditions, among others, attention deficit ...
Lintermans, Béatrice, Rondou, Pieter, Skieterska, Kamila, Van Craenenbroeck, Kathleen   +3 more
core   +21 more sources

L-methionine supplementation modulates IgM+ B cell responses in rainbow trout

Frontiers in Immunology, 2023
The interest in dietary amino acids (AAs) as potential immunomodulators has been growing the recent years, since specific AAs are known to regulate key metabolic pathways of the immune response or increase the synthesis of some immune-related proteins ...
Diana Martín, M. Camino Ordás, Inês Carvalho, Inês Carvalho, Patricia Díaz-Rosales, Noelia Nuñez-Ortiz, Samuel Vicente-Gil, Aitor Arrogante, Carlos Zarza, Marina Machado, Benjamín Costas, Benjamín Costas, Carolina Tafalla   +12 more
doaj   +1 more source

Dietary Lysine Levels Improved Antioxidant Capacity and Immunity via the TOR and p38 MAPK Signaling Pathways in Grass Carp, Ctenopharyngodon idellus Fry

Frontiers in Immunology, 2021
An 8-week rearing trial was designed to appraise the dietary lysine levels on intestinal antioxidant capacity and immunity of grass carp fry. Six practical diets were prepared with graded levels of lysine (1.44, 1.79, 1.97, 2.44, 2.56 and 2.87% dry ...
Dongyu Huang, Sahya Maulu, Mingchun Ren, Mingchun Ren, Hualiang Liang, Xianping Ge, Xianping Ge, Ke Ji, Heng Yu   +8 more
doaj   +1 more source

Development of a Hyperosmotic Stress Inducible Gene Expression System by Engineering the MtrA/MtrB-Dependent NCgl1418 Promoter in Corynebacterium glutamicum

Frontiers in Microbiology, 2021
Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Precise regulation of gene expression is crucial for metabolic balance and enhancing production of target molecules.
Jingwen Huang, Jingwen Huang, Jiuzhou Chen, Yu Wang, Tuo Shi, Xiaomeng Ni, Wei Pu, Jiao Liu, Yingyu Zhou, Yingyu Zhou, Ningyun Cai, Shuangyan Han, Ping Zheng, Jibin Sun, Jibin Sun   +14 more
doaj   +1 more source

Effect of increasing levels of threonine relative to lysine on the performance and meat quality of finishing pigs [PDF]

Animal Bioscience, 2021
Objective The present study aimed to evaluate the effects of varying standardized ileal digestible lysine:threonine (SID Lys:Thr) ratio in the diet on the performance and meat quality of finishing pigs.
Santi Devi Upadhaya, Sang Seon Lee, Sung Giu Jin, Zhenlong Wu, In Ho Kim   +4 more
doaj   +1 more source

Antioxidant Activity and Essential Amino acid Content of Bread Wheat (Triticum aestivum L.) Varieties

Journal of Agricultural Sciences, 2023
In recent years, consumption of healthy and nutritious products has come to the forefront with the increased consumers’ awareness because of sensitivity to human health.
Osman Erekul, Ali Yiğit
doaj   +1 more source

Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388. [PDF]

, 2020
COR388, a small-molecule lysine-gingipain inhibitor, is currently being investigated in a Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal disease.
Arastu-Kapur, Shirin, Araujo, Joseph, De Lannoy, Ines AM, Dominy, Stephen S, Ermini, Florian, Haditsch, Ursula, Holsinger, Leslie J, Lynch, Casey, Nguyen, Mai, Raha, Debasish, Ryder, Mark I   +10 more
core   +1 more source

Encapsulated crystalline lysine and DL-methionine have higher efficiency than the crystalline form in broilers

Poultry Science, 2020
Crystalline amino acids (AAs) exhibit high nutritional values when supplemented AA-deficient diets. However, the AAs in crystalline form in the diet are absorbed quickly than protein-bound AAs, which may take an effect on AA utilization efficiency.
Mingfa Sun, Hongchao Jiao, Xiaojuan Wang, Victoria A. Uyanga, Jingpeng Zhao, Hai Lin   +5 more
doaj   +1 more source

A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway. [PDF]

, 2013
The endoplasmic reticulum-associated degradation (ERAD) pathway is responsible for disposing misfolded proteins from the endoplasmic reticulum by inducing their ubiquitination and degradation.
Anania, Veronica, Bustos, Daisy, COSCOY, Laurent, Kirkpatrick, Donald, Lill, Jennie   +4 more
core   +3 more sources

Impact of varying starter amino acid density and energy on 42 d male Cobb MV × Cobb 500 broiler performance and processing

Journal of Applied Poultry Research, 2020
Summary: Previous research has shown that feeding high amino acid density (AAD) diets or increased AME improved broiler performance, though the relationship between AAD and AME on performance needs to be further explored. Therefore, the objective of this
R.A. Hirai, L. Mejia, C. Coto, J. Caldas, C.D. McDaniel, K.G.S. Wamsley   +5 more
doaj   +1 more source