Results 1 to 10 of about 177,630 (116)
Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation
Annual Review of Biochemistry, 2021 Protein lysine acetylation is an important posttranslational modification that regulates numerous biological processes. Targeting lysine acetylation regulatory factors, such as acetyltransferases, deacetylases, and acetyl-lysine recognition domains, has ...
Hening Lin, Miao Wang
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Review of Lysine Metabolism with a Focus on Humans.
Journal of Nutrition, 2020 Lysine cannot be synthesized by most higher organisms and, therefore, is an indispensable amino acid (IAA) that must be consumed in adequate amounts to maintain protein synthesis.
Dwight E Matthews
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p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis
Molecular Cell, 2018 SUMMARY Lysine 2-hydroxyisobutyrylation (Khib) is an evolutionarily conserved and widespread histone mark like lysine acetylation (Kac). Here we report that p300 functions as a lysine 2-hyroxyisobutyryltransferase to regulate glycolysis in response to ...
Xiaoling Li, Shuang Tang
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Effect of increasing levels of threonine relative to lysine on the performance and meat quality of finishing pigs [PDF]
Animal Bioscience, 2021 Objective The present study aimed to evaluate the effects of varying standardized ileal digestible lysine:threonine (SID Lys:Thr) ratio in the diet on the performance and meat quality of finishing pigs.
Santi Devi Upadhaya +4 more
doaj +1 more source
Animals, 2022 We postulated that the use of optimal levels and proportions of Arg and Met relative to a low or high concentration of Lys in diets for meat turkeys would reduce the occurrence of metabolic disturbances in the nervous tissue that can lead to ...
Magdalena Krauze +3 more
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Plants, 2022 Different strategies including the exogenous use of micronutrient-chelated amino acids are being employed for better crop yield with limited fresh water for irrigation. The present study was conducted to assess the effects of foliar-applied Zn-lysine (Zn-
Faisal Shehzad +4 more
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Lysine Catabolism Reprograms Tumour Immunity through Histone Crotonylation
Nature, 2023 Cancer cells rewire metabolism to favour the generation of specialized metabolites that support tumour growth and reshape the tumour microenvironment^ 1 , 2 .
Huairui Yuan +17 more
semanticscholar +1 more source
Class I histone deacetylases (HDAC1–3) are histone lysine delactylases
bioRxiv, 2021 Lysine l-lactylation [K(l-la)] is a newly discovered histone mark that can be stimulated under conditions of high glycolysis, such as the Warburg effect. K(l-la) is associated with functions that are different from the widely studied histone acetylation.
Carlos Moreno-Yruela +13 more
semanticscholar +1 more source
The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway
Science Advances, 2021 Widespread lysine β-hydroxybutyrylation plays diverse regulatory roles and is reversibly regulated by p300 and HDAC1/2. Metabolism-mediated epigenetic changes represent an adapted mechanism for cellular signaling, in which lysine acetylation and ...
He Huang +10 more
semanticscholar +1 more source
Efficiency of lysine utilization by growing meat quail
Poultry Science, 2021 The objective of present study was to estimate the efficiency of lysine utilization by meat quail of 21 to 35 d of age. A total of 500 meat quails were distributed in a completely randomized design in a 2 × 5 factorial arrangement, with 2 sexes (male and
J.C. Siqueira +7 more
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