Results 111 to 120 of about 945,171 (383)
Lysine-Targeted Inhibitors and Chemoproteomic Probes.
Annual Review of Biochemistry, 2019 Covalent inhibitors are widely used in drug discovery and chemical biology. Although covalent inhibitors are frequently designed to react with noncatalytic cysteines, many ligand binding sites lack an accessible cysteine.
A. Cuesta, J. Taunton
semanticscholar +1 more source
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
Advanced Biology, EarlyView.RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang +13 more
wiley +1 more source
Dietary lysine requirement of adult lambari ( Astyanax altiparanae ) (Garutti and Britski, 2000)
Revista Brasileira de Zootecnia, 2018 A 90-day feeding trial was conducted to estimate the dietary lysine requirement of adult lambari ( Astyanax altiparanae ), based on growth performance, whole-body composition, muscle development, and aspartate aminotransferase (AST) and alanine ...
Daniel Abreu Vasconcelos Campelo +4 more
doaj +1 more source
Molecular Lysine Tweezers Counteract Aberrant Protein Aggregation. [PDF]
, 2019 Molecular tweezers (MTs) are supramolecular host molecules equipped with two aromatic pincers linked together by a spacer (Gakh, 2018). They are endowed with fascinating properties originating from their ability to hold guests between their aromatic ...
Bitan, Gal +4 more
core
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Polypeptide gels incorporating the exotic functional aromatic amino acid 4-amino-L-phenylalanine [PDF]
, 2018 High-molecular-weight polypeptides with functional aromatic side chains, poly(4-amino-l-phenylalanine), were prepared by the metal-initiated polymerization of the Nα-carboxyanhydride of the corresponding amino acid, which is a microbial derivative of ...
Ali, Mohammad Asif +4 more
core +1 more source
Lysine catabolism reprograms tumour immunity through histone crotonylation
Nature, 2023 Huairui Yuan +17 more
semanticscholar +1 more source
Advanced Biology, EarlyView.Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams +7 more
wiley +1 more source
Archivos Latinoamericanos de Nutrición, 2008 Maíz de alta calidad de proteína (Quality Protein Maize, en inglés, QPM), con el doble de triptófano y lisina que el maíz convencional, ha mejorado el estado nutricional de niños severamente desnutridos. Su impacto en el crecimiento y morbilidad de niños
Eveling del Carmen Ortega Alemán +3 more
doaj
Lysine Supply Is a Critical Factor in Achieving Sustainable Global Protein Economy
Frontiers in Sustainable Food Systems, 2019 Production of animal-based protein is a significant global source of greenhouse gases, a major driver of agricultural land use and a source of nutrient loss to the environment. In this study, we provide a new assessment of the current sources of proteins
I. Leinonen +5 more
semanticscholar +1 more source