Results 51 to 60 of about 933,247 (382)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Variation in Protein Content and Amino Acids in the Leaves of Grain, Vegetable and Weedy Types of Amaranths

Agronomy, 2013
Malnutrition has affected almost 31% of pre-school children. This paper provides the information of nutritional values (leaf protein, 15 amino acids, biomass and leaf dry matter) of grain, vegetable and weedy types of amaranths (n = 76 accessions ...
Ryo Ohsawa, Shigeki Yoshida, Rita Andini
doaj   +1 more source

Kinetic determination of lysine in pharmaceutical sample [PDF]

Journal of the Serbian Chemical Society, 2002
Akinetic method for the determination of micro quantities of the amino acid lysine (Lys) is described in this paper. The catalytic activity of cobalt in the reaction of the oxidation of purpurin (1,2,4-trihydroxyanthraquinone PP) by hydrogen peroxide in ...
Mitić Snežana S., Miletić Gordana Ž., Petrović A.N., Tošić Snežana B.   +3 more
doaj   +1 more source

Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction [PDF]

, 2020
Adipocyte differentiation of bovine adipose-derived stem cells (ASC) was induced by foetal bovine serum (FBS), biotin, pantothenic acid, insulin, rosiglitazone, dexamethasone and 3-isobutyl-1-methylxanthine, followed by incubation in different media to ...
Aschenbach, Jörg R., Bermúdez- Peña, M. Carmen, Jurek, Sandra, Kolisek, Martin, Sandhu, Mansur A., Sponder, Gerhard, Trappe, Susanne   +6 more
core   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Diets for Dairy Cows with Different Proportions of Crude Protein Originating from Red Clover Silage versus Soybean Meal: Ruminal Degradation and Intestinal Digestibility of Amino Acids

Animals, 2021
The purpose was to assess the effect of exchanging crude protein (CP) of soybean meal (SBM) with red clover silage (RCS) in total mixed rations (TMR) on ruminal degradation and intestinal digestibility (ID) of essential amino acids (EAA).
Edwin Westreicher-Kristen, Ralf Blank, Monika Paschke-Beese, Wiebke Kühl, Siegfried Wolffram, Cornelia C. Metges, Andreas Susenbeth   +6 more
doaj   +1 more source

The effect of phase-feeding on the growth performance, carcass characteristics and nitrogen balance of growing and finishing pigs. [PDF]

, 2007
peer-reviewedA completely randomised design experiment was conducted to determine if grouphoused grower-finisher pigs (43.9 to 95 kg) show differences in performance and nitrogen utilisation when provided with a single high lysine diet (11 g/kg) or with ...
Garry, B.P., O'Doherty, John V., Pierce, K.M.   +2 more
core  

Small poly-L-lysines improve cationic lipid-mediated gene transfer in vascular cells in vitro and in vivo [PDF]

, 2007
The potential of two small poly-L-lysines ( sPLLs), low molecular weight sPLL ( LMW-L) containing 7 - 30 lysine residues and L18 with 18 lysine repeats, to enhance the efficiency of liposome-mediated gene transfer ( GT) with cationic lipid DOCSPER {[}1,3-
Adam Golda, Armeanu S, Bauters C, Boussif O, Capan Y, Choukri Mekkaoui, Eastman SJ, Gao X, Groth D, Guenzburg WH, Hofling B, Huehns TY, Huehns TY, Jaroslav Pelisek, Khalil IA, Li S, Mahato RI, Markus G. Engelmann, Miller AD, Nikol S, Nikol S, Nikol S, Nikol S, Nikol S, Ogris M, Pelisek J, Pelisek J, Pelisek J, Pelisek J, Pierre-Henri Rolland, Rainer Klocke, Shi Y, Sigrid Nikol, Sorgi FL, Vitiello L, Wadhwa MS, Wolfert MA   +36 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source