Results 51 to 60 of about 945,171 (383)

Efficient Multiplex Gene Repression by CRISPR-dCpf1 in Corynebacterium glutamicum

Frontiers in Bioengineering and Biotechnology, 2020
Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Multiplex control of metabolic pathway genes is crucial for maximizing biosynthesis of desired products.
Mingyue Li, Mingyue Li, Jiuzhou Chen, Yu Wang, Jiao Liu, Jingwen Huang, Jingwen Huang, Ning Chen, Ping Zheng, Jibin Sun   +9 more
doaj   +1 more source

Evaluation of in ovo feeding of low or high mixtures of cysteine and lysine on performance, intestinal morphology and physiological responses of thermal-challenged broiler embryos

Frontiers in Physiology, 2022
The objective of this study was to evaluate the effect of in ovo feeding cysteine, lysine or their combinations on the perinatal and post-hatch physiological responses of broiler embryos exposed to heat stress during incubation.
O. I. Ajayi, O. F. Smith, A. O. Oso, O. E. Oke   +3 more
doaj   +1 more source

The Unique Seed Protein Composition of Quality Protein Popcorn Promotes Growth of Beneficial Bacteria From the Human Gut Microbiome

Frontiers in Microbiology, 2022
The effects of fiber, complex carbohydrates, lipids, and small molecules from food matrices on the human gut microbiome have been increasingly studied.
Nate Korth, Nate Korth, Leandra Parsons, Leandra Parsons, Mallory J. Van Haute, Mallory J. Van Haute, Qinnan Yang, Qinnan Yang, Preston Hurst, Preston Hurst, James C. Schnable, James C. Schnable, James C. Schnable, David R. Holding, David R. Holding, Andrew K. Benson, Andrew K. Benson   +16 more
doaj   +1 more source

The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells [PDF]

, 2009
When the catalytic A subunits of the castor bean toxins ricin and Ricinus communis agglutinin (denoted as RTA and RCA A, respectively) are delivered into the endoplasmic reticulum (ER) of tobacco protoplasts, they become substrates for ER ...
Aldo Ceriotti, Allen, Bays, Brandizzi, Braun, Caldwell, Campbell, Carlson, Carter, Carvalho, Chaddock, Christopher J. Snowden, Contento, Dalal, Day, Deak, Deeks, Denecke, Denic, Di Cola, Di Cola, Feiler, Frigerio, Hellens, Hunter, J. Michael Lord, Jarosch, Jolliffe, Kirst, Klein, Kothe, Lee, Lord, Lorenzo Frigerio, Lynne M. Roberts, Maliga, Martinez, Meusser, Muller, Nicholas A. Jolliffe, Pedrazzini, Pimpl, Rabinovich, Rancour, Rape, Richard S. Marshall, Richly, Roberts, Roberts, Roberts, Romisch, Schmid, Schuberth, Simpson, Smalle, Swanson, Tabe, Tsai, Vashist, Vashist, Vitale, Wahlman, Wiertz, Wojcik, Wojcik, Worthington, Ye, Ye, Yoshida, Yoshida   +69 more
core   +2 more sources

LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice [PDF]

, 2015
Mammalian oocytes are arrested at prophase I until puberty when hormonal signals induce the resumption of meiosis I and progression to meiosis II.
Chen, T, Kerenyi, MA, Kim, J, Lin, K, Lu, Y, Orkin, SH, Shen, J, Singh, AK, Takata, Y   +8 more
core   +1 more source

Regulation of Cellular Metabolism by Protein Lysine Acetylation

Science, 2010
Metabolic Regulation Through Acetylation Covalent modification of lysine residues in various proteins in the nucleus is a recognized mechanism for control of transcription.
Shimin Zhao, W. Xu, Wenqing Jiang, Wei Yu, Yan Lin, Tengfei Zhang, Jun Yao, Li Zhou, Yaxue Zeng, Hong Li, Yixue Li, Jiong Shi, Wenlin An, S. Hancock, F. He, L. Qin, J. Chin, Pengyuan Yang, Xian Chen, Q. Lei, Y. Xiong, K. Guan   +21 more
semanticscholar   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin

Pharmaceutics, 2023
Acne is a chronic inflammatory skin disease that affects the quality of life of patients. Several treatments exist for acne, but their effectiveness tends to decrease over time due to increasing resistance to treatment and associated side effects.
Julie Leignadier, Marie Drago, Olivier Lesouhaitier, Magalie Barreau, Albert Dashi, Oliver Worsley, Joan Attia-Vigneau   +6 more
doaj   +1 more source

The degradation of L-lysine in guinea pig liver homogenate: formation of alpha-aminoadipic acid [PDF]

, 1948
A summary of the little that is known of the metabolism of lysine in animals is as follows: it is indispensable in the diet, its α-amino group does not participate in reversible transamination reaction in vivo (2), neither the L nor D form is attacked by
Borsook, Henry, Deasy, Clara L., Haagen-Smit, A. J., Keighley, Geoffrey, Lowy, Peter H.   +4 more
core   +1 more source

Lysine/RNA-interactions drive and regulate biomolecular condensation

Nature Communications, 2019
Cells form and use biomolecular condensates to execute biochemical reactions. The molecular properties of non-membrane-bound condensates are directly connected to the amino acid content of disordered protein regions.
T. Ukmar-Godec, Saskia Hutten, Matthew P. Grieshop, N. Rezaei-Ghaleh, Maria-Sol Cima-Omori, J. Biernat, E. Mandelkow, J. Söding, D. Dormann, M. Zweckstetter   +9 more
semanticscholar   +1 more source