Results 1 to 10 of about 3,037 (136)

Lysine succinylation, the metabolic bridge between cancer and immunity [PDF]

Genes and Diseases, 2023
Lysine succinylation is a naturally occurring post-translational modification (PTM) that regulates the stability and function of proteins. It can be regulated by enzymes such as SIRT5 and SIRT7.
Rui Shen, Hongyun Ruan, Shuye Lin, Bin Liu, Hang Song, Lu Li, Teng Ma   +6 more
doaj   +4 more sources

First comprehensive analysis of lysine succinylation in paper mulberry (Broussonetia papyrifera) [PDF]

BMC Genomics, 2021
Background Lysine succinylation is a naturally occurring post-translational modification (PTM) that is ubiquitous in organisms. Lysine succinylation plays important roles in regulating protein structure and function as well as cellular metabolism. Global
Yibo Dong, Ping Li, Ping Li, Chao Chen
doaj   +5 more sources

Enzymatic and metabolic regulation of lysine succinylation [PDF]

Genes and Diseases, 2020
Lysine succinylation (Ksucc), defined as a transfer of a succinyl group to a lysine residue of a protein, is a newly identified protein post-translational modification1–3.
Annapoorna Sreedhar, Elizabeth K. Wiese, Taro Hitosugi   +2 more
doaj   +4 more sources

Global analysis of protein lysine succinylation profiles in common wheat [PDF]

BMC Genomics, 2017
Background Protein lysine succinylation is an important post-translational modification and plays a critical regulatory role in almost every aspects of cell metabolism in both eukaryotes and prokaryotes.
Yumei Zhang, Guangyuan Wang, Limin Song, Ping Mu, Shu Wang, Wenxing Liang, Qi Lin   +6 more
doaj   +5 more sources

First Succinylome Profiling of Vibrio alginolyticus Reveals Key Role of Lysine Succinylation in Cellular Metabolism and Virulence [PDF]

Frontiers in Cellular and Infection Microbiology, 2021
Recent studies have shown that a key strategy of many pathogens is to use post-translational modification (PTMs) to modulate host factors critical for infection.
Fuyuan Zeng, Fuyuan Zeng, Fuyuan Zeng, Huanying Pang, Huanying Pang, Huanying Pang, Huanying Pang, Ying Chen, Ying Chen, Hongwei Zheng, Hongwei Zheng, Wanxin Li, Srinivasan Ramanathan, Rowena Hoare, Sean J. Monaghan, Xiangmin Lin, Jichang Jian, Jichang Jian, Jichang Jian, Jichang Jian   +19 more
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Deep_KsuccSite: A novel deep learning method for the identification of lysine succinylation sites [PDF]

Frontiers in Genetics, 2022
Identification of lysine (symbol Lys or K) succinylation (Ksucc) sites centralizes the basis for disclosing the mechanism and function of lysine succinylation modifications.
Xin Liu, Lin-Lin Xu, Ya-Ping Lu, Ting Yang, Xin-Yu Gu, Liang Wang, Yong Liu   +6 more
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Comprehensive Succinylome Profiling Reveals the Pivotal Role of Lysine Succinylation in Energy Metabolism and Quorum Sensing of Staphylococcus epidermidis [PDF]

Frontiers in Microbiology, 2021
BackgroundLysine succinylation is a newly identified posttranslational modification (PTM), which exists widely from prokaryotes to eukaryotes and participates in various cellular processes, especially in the metabolic processes.
Yiping Zhao, Yang Han, Yuzhe Sun, Zhendong Wei, Jialong Chen, Xueli Niu, Qian An, Li Zhang, Ruiqun Qi, Xinghua Gao   +9 more
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Lysine succinylation as a metabolic switch in cardiovascular diseases: Mechanistic insights and therapeutic perspectives [PDF]

Redox Biology
Cardiovascular diseases (CVDs) are life-threatening disorders arising from interactions between genetic and environmental factors, imposing a heavy global health burden with high morbidity and mortality.
Fei Mu, Haiyue Zhang, Rui Gong, Rui Lin, Meina Zhao, Xingru Tao, Lei Shang, Miaomiao Xi, Jinyi Zhao, Jingwen Wang   +9 more
doaj   +2 more sources

Systematic identification and comparative analysis of lysine succinylation between the green and white parts of chimeric leaves of Ananas comosus var. bracteatus [PDF]

BMC Genomics, 2020
Background Lysine succinylation, an important protein posttranslational modification (PTM), is widespread and conservative. The regulatory functions of succinylation in leaf color has been reported. The chimeric leaves of Ananas comosus var.
Meiqin Mao, Yanbin Xue, Yehua He, Xuzixing Zhou, Fatima Rafique, Hao Hu, Jiawen Liu, Lijun Feng, Wei Yang, Xi Li, Lingxia Sun, Zhuo Huang, Jun Ma   +12 more
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A Systematic Study of Lysine Succinylation in the Pathogenic Bacterium Vibrio harveyi in Aquatic Animals [PDF]

Molecules
Vibrio harveyi, a pathogenic vibrio, is ubiquitous and the most prevalent disease infecting tropical and subtropical mariculture animals in marine and estuarine environments.
Shuai Yang, Peng Zhou, Weijie Zhang, Yujia Zhang, Haiwei Guo, Yingzhu Wei, Xiaoxin Wen, Jichang Jian, Na Wang, Huanying Pang   +9 more
doaj   +2 more sources