Results 61 to 70 of about 4,792 (165)

Mycobacterium tuberculosis H37Ra: a surrogate for the expression of conserved, multimeric proteins of M.tb H37Rv [PDF]

, 2016
Additional file 3. Details of primers used, experimental and theoretical molecular weights, pI values and details of post-translational modifications in ...
Ajay Kumar, Ankit Sahu, Anushri Agnihotri, Chaaya Iyengar Raje, Himanshu Malhotra, Kalpesh Kumar Rajwadi, Manoj Kumar, Manoj Raje, Navdeep Sheokand, Naveen Bhagath, Navi Hasan, Pravinkumar Patil, Rachita Patkar, Vishant Mahendra Boradia   +13 more
core   +5 more sources

Stable isotopic labeling in proteomics [PDF]

, 2008
Labeling of proteins and peptides with stable heavy isotopes (deuterium, carbon-13, nitrogen-15, and oxygen-18) is widely used in quantitative proteomics.
Beynon, Blagoev, Borisov, Browder, Choe, Conrads, Craig, de Godoy, De Leenheer, Dean, Desiderio, Enoksson, Gerber, Gevaert, Gevaert, Gevaert, Gevaert, Gevaert, Gonzalez, Gronborg, Gruhler, Gygi, Hansen, Harsha, Hsu, Hsu, Hsu, Impens, Ji, Krijgsveld, Kuster, Kuster, Lange, Lanquar, Lopez-Otin, MacCoss, Mann, Mason, Mirzaei, Munchbach, Oda, Ong, Ong, Overall, Pan, Perkins, Pratt, Rivers, Ross, Schmidt, Schnolzer, Schulze, Scott, Selbach, Sethuraman, Staes, Staes, Tam, Van Damme, Van Hoof, Vande Walle, Wahlander, Wang, Washburn, Wiese, Wu, Zhang, Zhang, Zhang, Zhou   +69 more
core   +2 more sources

Quantitative Succinyl-Proteome Profiling of Camellia sinensis cv. ‘Anji Baicha’ During Periodic Albinism

Scientific Reports, 2017
Lysine succinylation is a novel dynamic and evolutionarily conserved post-translational modification (PTM) that regulates various biological processes. ‘Anji Baicha’ is an albino tea variety that exhibits temperature-based variability of leaf colour and ...
Yan-Xia Xu, Chen-Jia Shen, Jian-Qiang Ma, Wei Chen, Juan Mao, Yan-Yan Zhou, Liang Chen   +6 more
doaj   +1 more source

The interplay of post-translational modification and gene therapy [PDF]

, 2016
Several proteins interact either to activate or repress the expression of other genes during transcription. Based on the impact of these activities, the proteins can be classified into readers, modifier writers, and modifier erasers depending on ...
Azuh, Dominic E., Chinedu, S. N., Iweala, E. E. J., Ogunlana, Olubanke Olujoke, Osamor, V. C.   +4 more
core   +2 more sources

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s disease [PDF]

, 2022
Producción CientíficaAbnormalities in brain glucose metabolism and accumulation of abnormal protein deposits called plaques and tangles are neuropathological hallmarks of Alzheimer’s disease (AD), but their relationship to disease pathogenesis and to ...
Acosta, Diana, Anderson, Elizabeth T., Beal, M. Flint, Bhawal, Ruchika, Chen, Huanlian, Chen, Jianer, Eliezer, David, Gandy, Sam, Gibson, Gary E., Haroutunian, Vahram, Ivanova, Elena, Klein, William L., Lin, Hening, Sagdullaev, Botir T., Tapias, Victor, Viola, Kirsten L., Xu, Hui, Yang, Yun, Zhang, Sheng   +18 more
core   +1 more source

DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction

BMC Bioinformatics, 2020
Background Protein succinylation has recently emerged as an important and common post-translation modification (PTM) that occurs on lysine residues. Succinylation is notable both in its size (e.g., at 100 Da, it is one of the larger chemical PTMs) and in
Niraj Thapa, Meenal Chaudhari, Sean McManus, Kaushik Roy, Robert H. Newman, Hiroto Saigo, Dukka B. KC   +6 more
doaj   +1 more source

Extensive comparison of protein sequence-based bioinformatics applications for predicting lysine succinylation sites: a comparative review

Biotechnology & Biotechnological Equipment
Lysine succinylation is a post-translational modification that occurs when a succinyl group bonds with a lysine residue and changes the polarity of lysine from positive to negative, causing significant changes in the structure and functioning of proteins.
Hussam Alsharif
doaj   +1 more source

A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. [PDF]

, 2018
Mechanisms that integrate the metabolic state of a cell with regulatory pathways are necessary to maintain cellular homeostasis. Endogenous, intrinsically reactive metabolites can form functional, covalent modifications on proteins without the aid of ...
A Cleasby, A Dhar, A Kobayashi, A Moraru, A Shevchenko, A Uruno, AC Ruifrok, Arnab K. Chatterjee, BR Sabari, BT Weinert, CL Saw, Claudio Zambaldo, D Martinez Molina, DD Zhang, Emily N. Chin, FW Chaplen, Gihoon Lee, GP Sykiotis, GR Wagner, H Lin, Hwayoung Yun, Insha Ahmad, Jae Won Chang, John S. Coukos, JW Chang, Luke L. Lairson, M Ravichandran, MC Jaramillo, Michael J. Bollong, N Rabbani, N Rabbani, N Wakabayashi, Peter G. Schultz, Raymond E. Moellering, RE Moellering, RH Scannevin, S Nishimoto, S Tao, SC Lo, T Bücher, T Ogura, TB El-Abaseri, TO Khor, TW Lo, W Hur, W Hur, Y Mitsuishi, Z Zhang   +47 more
core   +2 more sources

Systematic analysis of the lysine succinylome in the model medicinal mushroom Ganoderma lucidum

BMC Genomics, 2019
Background Ganoderma lucidum, one of the best-known medicinal mushrooms in the world, produces more than 400 different bioactive compounds. However, the regulation of these bioactive compounds biosynthesis is still unclear.
Guangyuan Wang, Lili Xu, Hao Yu, Jie Gao, Lizhong Guo   +4 more
doaj   +1 more source

GPSuc: Global Prediction of Generic and Species-specific Succinylation Sites by aggregating multiple sequence features. [PDF]

PLoS ONE, 2018
Lysine succinylation is one of the dominant post-translational modification of the protein that contributes to many biological processes including cell cycle, growth and signal transduction pathways.
Md Mehedi Hasan, Hiroyuki Kurata
doaj   +1 more source