Results 121 to 130 of about 7,630 (250)
In situ, Reversible Gating of a Mechanosensitive Ion Channel through Protein-Lipid Interactions
Understanding the functioning of ion channels, as well as utilizing their properties for biochemical applications requires control over channel activity.
Anna Dimitrova +7 more
doaj +1 more source
Integrated analysis of extraction performance, phospholipid composition, oil quality, and multivariate relationships in green phospholipid recovery from crude rapeseed oil. ABSTRACT Rapeseed oil contains endogenous phospholipids (PLs) and other minor bioactive components, but conventional PL extraction methods commonly rely on chloroform‐based solvent ...
Fangcheng Shao +5 more
wiley +1 more source
Elevated Gestational IL-13 During Fetal Development Is Associated With Hyperactivity and Inattention in Eight-Year-Old Children [PDF]
Maternal immune activation (MIA) during fetal development leads to behavioral and psychological disorders in the offspring. Concomitantly, insufficient supply of polyunsaturated fatty acids (PUFAs) is suspected to contribute to early neuronal ...
Bergen, Martin von +7 more
core +1 more source
ABSTRACT Lipid metabolism reprogramming is a hallmark of cancer, yet the global lipidome of cancer cells and their extracellular vesicles (EVs) remains poorly understood. Using mass spectrometry, we analyzed the lipid profiles of a panel of human cancer and non‐cancer cell lines along with their secreted EVs.
Noélie Douanne +14 more
wiley +1 more source
Hydrodynamics of Diffusion in Lipid Membrane Simulations
By performing molecular dynamics simulations with up to 132 million coarse-grained particles in half-micron sized boxes, we show that hydrodynamics quantitatively explains the finite-size effects on diffusion of lipids, proteins, and carbon nanotubes in ...
Hummer, Gerhard +2 more
core +1 more source
Membrane lipid interactions in intestinal ischemia/reperfusion-induced Injury [PDF]
Ischemia, lack of blood flow, and reperfusion, return of blood flow, is a common phenomenon affecting millions of Americans each year. Roughly 30,000 Americans per year experience intestinal ischemia-reperfusion (IR), which is associated with a high ...
Anderson +146 more
core +1 more source
ABSTRACT This study aimed to explore the differences of peripheral blood (PB) and bone marrow serum lipidomic profiles in severe aplastic anemia (SAA) patients and their significance in predicting earlier immunosuppressive therapy (IST) response. A cohort of 11 newly diagnosed SAA patients and 15 healthy controls were enrolled between June 2020 and ...
Zexing Sun +11 more
wiley +1 more source
The dog lung surface-active fraction and phosphatidylcholine constituents were subjected to hydrolysis by Crotalus atrox phospholipase A2. Relative rates of hydrolysis were: dipalmitoyl glycerophosphorylcholine > phosphatidylcholine isolated from the ...
M.F. Frosolono +5 more
doaj +1 more source
Untargeted UPLC-MS Profiling Pipeline to Expand Tissue Metabolome Coverage: Application to Cardiovascular Disease. [PDF]
Metabolic profiling studies aim to achieve broad metabolome coverage in specific biological samples. However, wide metabolome coverage has proven difficult to achieve, mostly because of the diverse physicochemical properties of small molecules ...
Alun H. Davies +33 more
core +5 more sources
Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang +8 more
wiley +1 more source

