Results 71 to 80 of about 11,072 (207)

Metabolome response to temperature-induced virulence gene expression in two genotypes of pathogenic Vibrio parahaemolyticus [PDF]

open access: yes, 2016
Relative concentration of metabolites identified in Vibrio parahaemolyticus ATCC17802. (XLSX 113 kb)
Bo Feng   +4 more
core   +3 more sources

Lipidomic Analysis of Plasma Extracellular Vesicles from Adiponectin Deficient Mice or Metabolic Syndrome Patients Reveals Pro‐Oxidative and Pro‐Inflammatory Lipid Signatures Correlating with Metabolic Dysfunction

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Adiponectin deficiency remodels the lipid composition of plasma extracellular vesicles (EV), enriching polyunsaturated phospholipids and reducing lysophospholipids. These remodelled EV impact oxidative, inflammatory and metabolic function in recipient cells.
Sungji Cho   +13 more
wiley   +1 more source

Altered bactericidal activity aginst staphylococcus aureus in tuberculous bronchoalveolr lavage fluids [PDF]

open access: yes, 1994
Altered bactericidal activity against Staphylococcus aureus in tuberculous bronchoalveolar lavage fluids. P. Selvaraj, N. Venkataprasad, V.K. Vijayan, P.R. Narayanan. ©ERS Journals Ltd 1994.
Narayanan, P R   +3 more
core  

Analytic models for mechanotransduction: gating a mechanosensitive channel [PDF]

open access: yes, 2003
Analytic estimates for the forces and free energy generated by bilayer deformation reveal a compelling and intuitive model for MscL channel gating analogous to the nucleation of a second phase.
Betanzos   +22 more
core   +2 more sources

The many dimeric faces of Lys49 PLA2‐like proteins: Conformational plasticity and membrane binding drive functional dimer states

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Lys49 secreted phospholipase A2‐like proteins (sPLA2s) are major myotoxins in viperid snake venoms, causing rapid muscle damage in envenomation. Beyond their clinical relevance, these small non‐catalytic proteins provide a model to study how quaternary structure and conformational dynamics enable catalysis‐independent membrane disruption ...
Diane C. A. Lima   +4 more
wiley   +1 more source

The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation[S]

open access: yesJournal of Lipid Research, 2011
Platelet activation initiates an upsurge in polyun­saturated (18:2 and 20:4) lysophosphatidic acid (LPA) production. The biochemical pathway(s) responsible for LPA production during blood clotting are not yet fully understood.
Alyssa L. Bolen   +13 more
doaj   +1 more source

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes [PDF]

open access: yes, 2020
BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders.
Davidson, Nicholas O   +2 more
core   +1 more source

Lysophospholipid G Protein-coupled Receptors [PDF]

open access: yesJournal of Biological Chemistry, 2004
The many biological responses documented for lysophospholipids that include lysophosphatidic acid and sphingosine 1-phosphate can be mechanistically attributed to signaling through specific G protein-coupled receptors. At least nine receptors have now been identified, and the total number is likely to be larger.
Brigitte, Anliker, Jerold, Chun
openaire   +2 more sources

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract FAALs (fatty acyl‐AMP ligases) recruit and incorporate fatty acids during the biosynthesis of secondary metabolites. Their diversity, distribution, and substrate specificity remain poorly understood, which limits functional predictions from sequence data.
Anne Liong   +2 more
wiley   +1 more source

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 515-528, February 2026.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper   +6 more
wiley   +1 more source

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