Results 91 to 100 of about 7,391 (220)

Therapeutic Effects and Mechanisms of Fucoidan on Dyslipidemia in Obese Mice

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
In the present study, fucoidan (50 mg/kg/day) did not alter HFD‐driven weight gain or food intake, but significantly decreased serum total cholesterol (TC). Fucoidan reduced hepatic triglyceride, TC, and lipid droplets, improving hepatic lipid accumulation.
Lizhi Peng, Ruiming Li, Ruting Zheng, Ziqiong Liao, Daohuang Luo, Yuting Zeng, Jiaqi Liu, Qiaoling Kong, Jicai Lai   +8 more
wiley   +1 more source

Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization [PDF]

The rapid intraerythrocytic replication of Plasmodium falciparum, a deadly species of malaria parasite, requires a quick but constant supply of phospholipids to support marked cell membrane expansion. In the malarial parasite, many enzymes functioning in
H. Hayakawa, Eri Saki, Inaoka, Daniel Ken, Yoshida, Minako, Tokumasu, Fuyuki, Shindou, Hideo, Sakura, Takaya, Usukura, Jiro, Miyazaki, Shinya, Kita, Kiyoshi, Tokuoka, Suzumi M., Fukumoto, Junpei   +10 more
core   +2 more sources

Lysophospholipid Metabolism and Signalling in Non-Alcoholic Fatty Liver Disease

, 2022
Non-alcoholic liver disease (NAFLD) constitutes a global health pandemic. It is estimated that about 25% of the world’s population suffers from NAFLD. In the long-term, a subgroup of the patients can develop inflammation and fibrosis.
Papadopoulos,Charalambos, Anagnostopoulos,Konstantinos, Papazoglou,Dimitrios, Tentes,Ioannis   +3 more
core   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Measurement of lysophospholipid transport across the membrane using escherichia coli spheroplasts

, 2019
© Springer Science+Business Media, LLC, part of Springer Nature 2019. In the inner membrane of Gram-negative bacteria lysophospholipid transporter (LplT) and the bifunctional acyl-acyl carrier protein (ACP) synthetase/2-acylglycerolphosphoethanolamine ...
Bogdanov M., Zheng L., Lin Y.
core  

Lysophospholipid Remodeling Mediated by the LplT and Aas Protein Complex in the Bacterial Envelope

Lysophospholipid transporter LplT and acyltransferase Aas consist of a lysophospholipid-remodeling system ubiquitously found in gram-negative microorganisms.
Du, Guangwei, Niu, Wei, Vu, Trung, Bogdanov, Mikhail, Zheng, Lei   +4 more
core   +1 more source

Alterations in endo-lysosomal function induce similar hepatic lipid profiles in rodent models of drug-induced phospholipidosis and Sandhoff disease

Journal of Lipid Research, 2017
Drug-induced phospholipidosis (DIPL) is characterized by an increase in the phospholipid content of the cell and the accumulation of drugs and lipids inside the lysosomes of affected tissues, including in the liver.
Emmanuelle Lecommandeur, David Baker, Timothy M. Cox, Andrew W. Nicholls, Julian L. Griffin   +4 more
doaj   +1 more source

Small Extracellular Vesicle and Total Lipid Profiles Provide a Diagnostic Advantage Over CA‐125 Across Ovarian Cancer Subtypes

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Small extracellular vesicle (sEV) lipid profiles outperform CA‐125 across ovarian cancer histotypes, achieving accuracy up to 0.73 in differential diagnosis and 0.94 in screening. In patients with normal CA‐125 levels, sEV lipids maintain discriminative performance where CA‐125 alone fails. ABSTRACT Ovarian cancer remains the most lethal gynaecological
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Lewis Perrin, Rohan Lourie, Vaibhavi Joshi, Amy E. McCart Reed, Kaltin Ferguson, Aase Handberg, Andreas Möller, Carlos Salomon   +11 more
wiley   +1 more source

x‐Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+‐Stabilized Expanded Active‐Site Cleft Adapted for Phospholipid Binding

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1543-1550, September 2026.
ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake, Tatsuya Hirata, Shunsuke Nomura, Kenji Konishi, Kazunari Yoneda, Shin‐ichi Sakasegawa, Haruhiko Sakuraba   +6 more
wiley   +1 more source

Systems‐Level Plant Responses Reveal Pseudomonas‐Mediated Growth Promotion in Brachypodium Under Nitrogen Limitation

Plant, Cell &Environment, Volume 49, Issue 9, Page 6396-6412, September 2026.
ABSTRACT Plant growth–promoting bacteria can enhance plant performance under nutrient limitation, yet the underlying plant molecular responses remain incompletely resolved. We investigated growth promotion by Pseudomonas koreensis in Brachypodium distachyon under contrasting nitrogen (N) regimes using time‐resolved phenotyping, elemental analysis ...
Stefan Sanow, Melissa Mantz, Holger Wissel, Atul Bhatnagar, Elena Sturm, Jana M. Kelm, Robert Walker, Andreas Lücke, Gabriel Schaaf, Pitter F. Huesgen, Ute Roessner, Michelle Watt, Borjana Arsova   +12 more
wiley   +1 more source