Results 101 to 110 of about 6,898 (217)

The molecular mechanism by which saturated lysophosphatidylcholine attenuates the metastatic capacity of melanoma cells

FEBS Open Bio, 2016
Lysophophatidylcholine (LysoPC) is an abundant constituent in human plasma. Patients with malignant cancer diseases have attenuated LysoPC plasma levels, and thus LysoPC has been examined as a metabolic biomarker for cancer prediction.
Thomas Ross, Bastian Jakubzig, Manuel Grundmann, Ulrich Massing, Evi Kostenis, Martin Schlesinger, Gerd Bendas   +6 more
doaj   +1 more source

International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature

, 2002
The lysophospholipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), are now recognized as important extracellular signaling molecules. These lipid mediators are pleiotropic; among the most common cellular responses are mitogenesis, cell
Chun, Jerold, Goetzl, Edward J, Hla, Timothy, Moolenaar, Wouter, Pyne, Susan, Igarashi, Yasuyuki, Lynch, Kevin R, Tigyi, Gabor   +7 more
core  

Effect of dietary lysophospholipid supplementation on growth performance, serum lipids, small intestine morphology and caeca microflora in broiler chickens

Veterinary Medicine and Science
Background The digestibility of animal fats and oils is limited by a reduction in the production and secretion of lipase and bile salts in young chickens.
AliAkbar Salari, Abolghasem Golian, Ahmad Hassanabadi   +2 more
doaj   +1 more source

Value of Lysophospholipid Metabolites in Prognosis of Major Adverse Cardiac Events in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention: a Prospective Cohort Study [PDF]

Background Percutaneous coronary intervention (PCI) is the main treatment for acute coronary syndrome (ACS), but some patients may experience recurrent major cardiovascular events (MACE) after the treatment.
SUN Xuechun, DU Zhiyong, YU Huahui, LYU Qianwen, JIAO Xiaolu, WANG Yu, QIN Yanwen
core   +1 more source

Lipase-catalyzed production of lysophospholipids

Oilseeds and fats, crops and lipids, 2017
Lysophospholipids, such as lysophosphatidic acid or lysophosphatidylcholine, are important bioactive lipids, involved in various normal and pathological cellular processes.
Mnasri Taha, Hérault Josiane, Gauvry Laurent, Loiseau Céline, Poisson Laurent, Ergan Françoise, Pencréac'h Gaëlle   +6 more
doaj   +1 more source

Lysophospholipid (S1P) receptors in GtoPdb v.2025.3

Sphingosine 1-phosphate (S1P) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid receptors [98]) are activated by the endogenous lipid sphingosine 1-phosphate (S1P). Originally cloned as orphan members of the endothelial
Blaho, Victoria, Herr, Deron R., Chun, Jerold, Kihara, Yasuyuki, Jones, Danielle   +4 more
core   +1 more source

Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells

, 2012
Synthetic alkyl-lysophospholipids represent a family of promising anticancer drugs that induce apoptosis in a variety of tumor cells. Here we have found a differential subcellular distribution of the alkyl-lysophospholipid edelfosine in leukemic and ...
Mollinedo, Faustino, Nieto-Miguel, Teresa, Gajate, Consuelo   +2 more
core   +1 more source

Analysis of lysophospholipid content in low phytate rice mutants

, 2017
As a fundamental component of nucleic acids, phospholipids, and adenosine triphosphate, phosphorus (P) is critical to all life forms, however, the molecular mechanism of P translocation and distribution in rice grains are still not understood. Here, with
Rose, Terry J, Waters, Daniel LE, Tong, Chuan, Tan, Yuanyuan, Chen, Yaling, Liu, Lei   +5 more
core   +1 more source

Plasma C24:0- and C26:0-lysophosphatidylcholines are reliable biomarkers for the diagnosis of peroxisomal β-oxidation disorders

Journal of Lipid Research
The gold-standard diagnostic test for peroxisomal disorders (PDs) is plasma concentration analysis of very long-chain fatty acids (VLCFAs). However, this method’s time-consuming nature and limitations in cases which present normal VLCFA levels ...
Blai Morales-Romero, José Manuel González de Aledo-Castillo, Cristina Fernández Sierra, Carmen Martínez Carreira, Carles Zaragoza Bonet, Rosa Fernández Bonifacio, Maria Antònia Caro Miró, Ana Argudo-Ramírez, Rosa María López Galera, Judit García-Villoria   +9 more
doaj   +1 more source

Lysophospholipid metabolism facilitates Toll-like receptor 4 membrane translocation to regulate the inflammatory response

, 2008
Sepsis, an overwhelming inflammatory response to infection, is a major cause of morbidity and mortality worldwide and has no specific therapy. Phospholipid metabolites, such as lysophospholipids, have been shown to regulate inflammatory responses in ...
Jones, Simon, Wondwossen Abate, Jackson, S. K., Jackson, Simon K., Abate, Wondwossen, Parton, Joan, Simon Jones, John L Harwood, Abate, W., Joan Parton, Harwood, John L., Jones, S., Simon K Jackson   +12 more
core   +1 more source