Results 111 to 120 of about 6,898 (217)

The effect of membrane active agents on human leukaemia cells [PDF]

, 1998
This Thesis investigates the effect of membrane-active agents, such as synthetic ether lipids (SEL), local anaesthetics and polyunsaturated fatty acids (PUFAs) on human leukaemia cells.
Jones, Eirian Wynne
core  

Cytogenetic effects of an alkyl-lysophospholipid derivative in human peripheral lymphocytes exposed in vitro and in vivo.

, 1983
Chromosome analyses were carried out in human lymphocytes exposed to an antitumor alkyl-lysophospholipid (ALP) in vitro and in vivo. There was no evidence for a significant clastogenic effect or incidence of an increased sister-chromatid exchange (SCE ...
Schmid, E., Bauchinger, M., Dresp, J.H., Berdel, W.E.   +3 more
core   +1 more source

Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing

, 2007
The bioactive lysophospholipids, primarily lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P), are recent additions to the list of potent mediators of tissue repair and wound healing. In this review, we highlight the diverse actions of LPA and
Lanning, David A., Diegelmann, Robert F., Watterson, Kenneth R., Spiegel, Sarah   +3 more
core   +1 more source

Lysophospholipid Acyltransferases Mediate Phosphatidylcholine Diversification to Achieve the Physical Properties Required In Vivo

, 2014
SummaryThe acyl-chain composition of the major mammalian phospholipid phosphatidylcholine (PC) is distinct in various tissues. Although it was classically suggested that PC diversity is acquired through acyl-chain remodeling, the mechanisms and ...
Mishina, Masayoshi, Eto, Miki, Ishii, Satoshi, Shindou, Hideo, Kita, Yoshihiro, Sakimura, Kenji, Harayama, Takeshi, Otsubo, Eiji, Shimizu, Takao, Hishikawa, Daisuke   +9 more
core   +1 more source

Control of free arachidonic acid levels by phospholipases A2 and lysophospholipid acyltransferases

, 2013
El pdf del artículo es la versión pre-print.Arachidonic acid (AA) and its oxygenated derivatives, collectively known as the eicosanoids, are key mediators of a wide variety of physiological and pathophysiological states.
Astudillo, Alma M., Balgoma, David, Balboa, María A., Balsinde, Jesús, Pérez-Chacón, Gema   +4 more
core   +1 more source

From Classical to Alternative Pathways of 2-Arachidonoylglycerol Synthesis: AlterAGs at the Crossroad of Endocannabinoid and Lysophospholipid Signaling

2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized on demand in postsynaptic membranes through the sequential action of phosphoinositide-specific ...
Stéphanie Trudel, Salles, Juliette, Ausseil, Jérôme, Hugues Chap, Jean-Pierre Salles, Bernard Payrastre, Briand-Mésange, Fabienne, Trudel, Stéphanie, Dahan, Lionel, Jérôme Ausseil, Isabelle Gennero, Juliette Salles, Payrastre, Bernard, Lionel Dahan, Salles, Jean-Pierre, Chap, Hugues, Gennero, Isabelle, Fabienne Briand-Mésange   +17 more
core   +1 more source

Imidazoline receptor antisera-selected protein: a unique modulator of neuronal differentiation.

, 2008
The imidazoline I1 receptor (I1-R) is a novel receptor found primarily in the brain and nervous tissue where it modulates neurotransmission. It is named for its high affinity for compounds with an imidazoline structure such as the anti-hypertensive drugs,
Dehle, Francis Christian
core  

Regulatory roles of bioactive lipids in vascular homeostasis and remodeling

Medical Review
Bioactive lipids are low-abundance, rapidly acting signaling molecules that orchestrate vascular homeostasis and remodeling through a closed-loop cycle of synthesis, localization, receptor/effector sensing, and inactivation.
Yang Jie, Xiao Haiyan, Zhang Zhongze, Zhang Liuyang, Zhang Xu   +4 more
doaj   +1 more source

Concurrent Phenylalanine Hydroxylase-Related Disorder and Celiac: A Rare Co-occurrence With Implications for Clinical Management. [PDF]

Ann Intern Med Clin Cases
Jensen J, Merritt E, Olarewaju BA, Tejon JB, Asif MB, Lanpher BC, Osundiji MA.   +6 more
europepmc   +1 more source

Hepatic lipid quantity and quality in type 2 diabetes mellitus. [PDF]

Front Pharmacol
Shimizu K, Shindou H, Tomita K, Mizuguchi H.   +3 more
europepmc   +1 more source