Results 21 to 30 of about 2,643 (172)

Pseudomonas syringae lytic transglycosylase HrpH interacts with host ubiquitin ligase ATL2 to modulate plant immunity

Cell Reports
Summary: Pseudomonas syringae deploys a type III secretion system (T3SS) to deliver effector proteins to facilitate infection of plant cells; however, little is known about the direct interactions between T3SS components and plants.
Jun-Zhou Li, Yi-Lin Gu, Wei Zhang, Shen Cong, Ruo-Na Wang, Yi-Nan Ma, Ya Jin, Hai-Lei Wei   +7 more
doaj   +2 more sources

Soluble lytic transglycosylase SLT of Francisella novicida is involved in intracellular growth and immune suppression. [PDF]

PLoS ONE, 2019
Francisella tularensis, a category-A bioterrorism agent causes tularemia. F. tularensis suppresses the immune response of host cells and intracellularly proliferates.
Takemasa Nakamura, Takashi Shimizu, Akihiko Uda, Kenta Watanabe, Masahisa Watarai   +4 more
doaj   +2 more sources

Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile [PDF]

mBio, 2018
Clostridium difficile is the major etiologic agent of antibiotic-associated intestinal disease. Pathogenesis of C. difficile is mainly attributed to the production and secretion of toxins A and B.
Sandra Wydau-Dematteis, Imane El Meouche, Pascal Courtin, Audrey Hamiot, René Lai-Kuen, Bruno Saubaméa, François Fenaille, Marie-José Butel, Jean-Louis Pons, Bruno Dupuy, Marie-Pierre Chapot-Chartier, Johann Peltier   +11 more
doaj   +2 more sources

Important role of a putative lytic transglycosylase Cj0843c in β-lactam resistance in Campylobacter jejuni [PDF]

Frontiers in Microbiology, 2015
Beta-lactam antibiotics are an important class of antibiotics for treating bacterial infections. Despite prevalent β-lactam resistance in Campylobacter jejuni, the leading bacterial cause of human diarrhea in developed countries, molecular mechanism of β-
Ximin eZeng, Barbara eGillespie, Jun eLin   +2 more
doaj   +2 more sources

Glycan strand cleavage by a lytic transglycosylase, MltD contributes to the expansion of peptidoglycan in Escherichia coli. [PDF]

PLoS Genetics
Peptidoglycan (PG) is a protective sac-like exoskeleton present in most bacterial cell walls. It is a large, covalently crosslinked mesh-like polymer made up of many glycan strands cross-bridged to each other by short peptide chains.
Moneca Kaul, Suraj Kumar Meher, Krishna Chaitanya Nallamotu, Manjula Reddy   +3 more
doaj   +2 more sources

The catalytic domain of a bacterial lytic transglycosylase defines a novel class of lysozymes [PDF]

Proteins: Structure, Function, and Bioinformatics, 1995
AbstractThe 70‐kDa soluble lytic transglycosylase (SLT70) from Escherichia coli is a bacterial exo‐muramidase that cleaves the cell wall peptidoglycan, producing 1,6‐anhydro‐muropeptides. The X‐ray structure of SLT70 showed that one of its domains is structurally related to lysozyme, although there is no obvious similarity in amino acid sequence.
Thunnissen, Andy-Mark W.H., Isaacs, Neil W., Dijkstra, Bauke W.   +2 more
openaire   +4 more sources

Structural insights into MltB from Acinetobacter baumannii: a conserved catalytic tunnel with unique domain arrangement [PDF]

IUCrJ
Lytic transglycosylases (LTs) play a central role in bacterial cell wall remodeling by cleaving the β-1,4-glycosidic bond in peptidoglycan via a non-hydrolytic mechanism, producing 1,6-anhydroMurNAc termini crucial for recycling and signaling. Among LTs,
Hyunseok Jang, Chang Min Kim, Chang Sup Lee, Hyun Ho Park   +3 more
doaj   +2 more sources

A Francisella novicida Mutant, Lacking the Soluble Lytic Transglycosylase Slt, Exhibits Defects in Both Growth and Virulence [PDF]

Frontiers in Microbiology, 2019
Francisella tularensis is the causative agent of tularemia and has gained recent interest as it poses a significant biothreat risk. F. novicida is commonly used as a laboratory surrogate for tularemia research due to genetic similarity and susceptibility
Beth A. Bachert, Sergei S. Biryukov, Jennifer Chua, Sabrina A. Rodriguez, Ronald G. Toothman, Christopher K. Cote, Christopher P. Klimko, Melissa Hunter, Jennifer L. Shoe, Janice A. Williams, Kathleen A. Kuehl, Fabrice V. Biot, Joel A. Bozue   +12 more
doaj   +2 more sources

An MltA-Like Lytic Transglycosylase Secreted by Bdellovibrio bacteriovorus Cleaves the Prey Septum during Predatory Invasion. [PDF]

J Bacteriol, 2023
Lytic transglycosylases cut peptidoglycan backbones, facilitating a variety of functions within bacteria, including cell division, pathogenesis, and insertion of macromolecular machinery into the cell envelope.
Banks EJ, Lambert C, Mason SS, Tyson J, Radford PM, McLaughlin C, Lovering AL, Sockett RE.   +7 more
europepmc   +2 more sources

Lytic transglycosylase Slt of Pseudomonas aeruginosa as a periplasmic hub protein. [PDF]

Protein Sci
AbstractPeptidoglycan is a major constituent of the bacterial cell wall. Its integrity as a polymeric edifice is critical for bacterial survival and, as such, it is a preeminent target for antibiotics. The peptidoglycan is a dynamic crosslinked polymer that undergoes constant biosynthesis and turnover.
Avila-Cobian LF, De Benedetti S, Hoshino H, Nguyen VT, El-Araby AM, Sader S, Hu DD, Cole SL, Kim C, Fisher JF, Champion MM, Mobashery S.   +11 more
europepmc   +3 more sources