Lytic transglycosylases in macromolecular transport systems of Gram-negative bacteria
The cell wall of Gram-negative bacteria is essential for the integrity of the bacterial cell but also imposes a physical barrier to trans-envelope transport processes in which DNA and/or proteins are taken up or secreted by complex protein assemblies.
Günther Koraimann
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Structure of the Bacteriophage φKZ Lytic Transglycosylase gp144 [PDF]
Lytic transglycosylases are enzymes that act on the peptidoglycan of bacterial cell walls. They cleave the glycosidic linkage between N-acetylmuramoyl and N-acetylglucosaminyl residues with the concomitant formation of a 1,6-anhydromuramoyl product. The x-ray structure of the lytic transglycosylase gp144 from the Pseudomonas bacteriophage phi KZ has ...
Andrei Fokine +4 more
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Bactericidal effect of nanostructures via lytic transglycosylases of Escherichia coli
The time profiles of active cell ratios depended on the growth phase and the absence of some lytic transglycosylases of E. coli. Significant cell damage was not found on the autolysis inhibition condition.
Soma Mimura +4 more
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Lytic transglycosylase repertoire diversity enables intrinsic antibiotic resistance and daughter cell separation in Escherichia coli under acidic stress. [PDF]
Son JE, Park SH, Choi U, Lee C-R.
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X-ray Structure of Catenated Lytic Transglycosylase SltB1. [PDF]
Formation of catenanes by proteins is rare, with few known examples. We report herein the X-ray structure of a catenane dimer of lytic transglycosylase SltB1 of Pseudomonas aeruginosa. The enzyme is soluble and exists in the periplasmic space, where it modifies the bacterial cell wall.
Domínguez-Gil T +5 more
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A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. [PDF]
Williams AH +7 more
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Biochemical and Phylogenetic Study of SltF, a Flagellar Lytic Transglycosylase from Rhodobacter sphaeroides. [PDF]
García-Ramos M +4 more
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Deletion of Lytic Transglycosylases Increases Beta-Lactam Resistance in Shewanella oneidensis [PDF]
Production of chromosome-encoded β-lactamases confers resistance to β-lactams in many Gram-negative bacteria. Some inducible β-lactamases, especially the class C β-lactamase AmpC in Enterobacteriaceae, share a common regulatory mechanism, the ampR-ampC paradigm.
Jianhua Yin +5 more
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The Lytic Transglycosylases of Neisseria gonorrhoeae [PDF]
Neisseria gonorrhoeae encodes five lytic transglycosylases (LTs) in the core genome, and most gonococcal strains also carry the gonococcal genetic island that encodes one or two additional LTs. These peptidoglycan (PG)-degrading enzymes are required for a number of processes that are either involved in the ...
Yolande A, Chan +2 more
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EloR interacts with the lytic transglycosylase MltG at midcell in Streptococcus pneumoniae R6. [PDF]
AbstractThe ellipsoid shape ofStreptococcus pneumoniaeis determined by the synchronized actions of the elongasome and the divisome, which have the task of creating a protective layer of peptidoglycan (PG) enveloping the cell membrane. The elongasome is necessary for expanding PG in the longitudinal direction whereas the divisome synthesizes the PG that
Winther AR +4 more
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