Cloning and controlled overexpression of the gene encoding the 35 kDa soluble lytic transglycosylase from Escherichia coli [PDF]
, 1995 The lytic transglycosylases of Escherichia coli are involved in peptidoglycan metabolism and resemble the lysozymes not only in activity, but in the case of the 70 kDa soluble lytic transglycosylase (Slt70), also structurally.
Dijkstra, Arnoud J. +2 more
core +1 more source
Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]
, 2016 American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S. +4 more
core +2 more sources
Lytic transglycosylases: Bacterial space-making autolysins
The International Journal of Biochemistry & Cell Biology, 2008 Lytic transglycosylases are an important class of bacterial enzymes that act on peptidoglycan with the same substrate specificity as lysozyme. Unlike the latter enzymes, however, the lytic transglycosylases are not hydrolases but instead cleave the glycosidic linkage between N-actetylmuramoyl and N-acetylglucosaminyl residues with the concomitant ...
Scheurwater, Edie +2 more
openaire +4 more sources
A SpoIID Homolog Cleaves Glycan Strands at the Chlamydial Division Septum
mBio, 2019 Chlamydiales species are obligate intracellular bacteria lacking a classical peptidoglycan sacculus but relying on peptidoglycan synthesis for cytokinesis.
Nicolas Jacquier +5 more
doaj +1 more source
Frontiers in Microbiology, 2021 Assembly of the bacterial flagellar rod, hook, and filament requires penetration through the peptidoglycan (PG) sacculus and outer membrane. In most β- and γ-proteobacteria, the protein FlgJ has two functional domains that enable PG hydrolyzing activity ...
Hui Xu +6 more
doaj +1 more source
Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa. [PDF]
Proc Natl Acad Sci U S A, 2018 Significance β-Lactam antibiotics are currently the most broadly used class of antibiotics. These antibiotics prevent bacterial cell wall from cross-linking, which leads to the accumulation of long non–cross-linked strands of peptidoglycan.
Lee M +11 more
europepmc +5 more sources
Subcellular localization and processing of the lytic transglycosylase of the conjugative plasmid R1 [PDF]
FEBS Letters, 2000 Protein P19 encoded by the conjugative resistance plasmid R1, is essential for efficient conjugative DNA transfer and infection by the pilus‐specific RNA phage R17. Based on sequence homologies P19 belongs to a family of lysozyme‐like virulence factors which are found in type III and type IV secretion systems.
Günther Koraimann +3 more
openaire +3 more sources
The bacterial septal ring protein RlpA is a lytic transglycosylase that contributes to rod shape and daughter cell separation in Pseudomonas aeruginosa. [PDF]
Mol Microbiol, 2014 Jorgenson MA +4 more
europepmc +3 more sources
Functional analysis of SleC from Clostridium difficile: an essential lytic transglycosylase involved in spore germination. [PDF]
Microbiology (Reading), 2014 Gutelius D +3 more
europepmc +3 more sources
Viruses, 2020 Staphylococcal bacteriophages of the Kayvirus genus are candidates for therapeutic applications. One of their proteins, Tgl, is slightly similar to two staphylococcal virulence factors, secreted autolysins of lytic transglycosylase motifs IsaA and SceD ...
Aleksandra Głowacka-Rutkowska +5 more
doaj +1 more source