Results 151 to 160 of about 26,727 (247)

Encephalopathy: Cause, Pathogenesis, and Treatment

MedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv, Xia Zhong, Ruirui Shang, Linghui Kong, Yufei Huang, Yuexiang Ma, Jing Teng, Sheng Wei   +7 more
wiley   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, Volume 2, Issue 2, Page 343-370, June 2026.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

Anticorpos Anti-Receptor De Fosfolipase A2 Em Pacientes Brasileiros Com Glomerulopatias

, 2018
Introduction: Recently Great Progress Has Been Made In Understanding The Pathogenesis Of Membranous Glomerulopathy With The Discovery Of Antibodies Against The M-Type Receptor Of Phospholipase A2 (M-Type Phospholipase A2 Receptor, Pla2r) In Serum And ...
Santos Neto, Cicero De Oliveira [UNIFESP]
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Nutritional Composition and Potential Actions of Bioactive Compounds From Wild Laurus nobilis in the Management of Pulmonary Fibrosis‐Induced Cardiopathy in Rats

Molecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
ABSTRACT Wild Laurus nobilis fruits, a well‐known dietary plant, have been documented to alleviate cardiopathy associated with pulmonary fibrosis, but the underlying mechanisms remain largely unspecified. This current study aimed to investigate the potential therapeutic effects of wild L.
Saber Jedidi, Ala Ayari, Aouar Abidi, Houcem Sammari, Nourhène Dhawefi, Hichem Sebai   +5 more
wiley   +1 more source

Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi, Xi Liu, Xi Zhang, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Prevalence of serum anti M-type phospholipase A2 receptor antibody in primary membranous nephropathy: A single center experience. [PDF]

Indian J Nephrol, 2016
Gopalakrishnan N, Abeesh P, Dineshkumar T, Murugananth S, Sakthirajan R, Raman GS, Dhanapriya J, Balasubramaniyan T, Haris M.   +8 more
europepmc   +1 more source

Phytochemicals in Asthma Management: Mechanism, Translational Gap and Clinical Integration

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
The phytochemicals including flavonoids, alkaloids, terpenoids, and saponins modulate inflammatory, oxidative, and immune pathways in asthma. It highlights their mechanisms of action, translational challenges, advanced formulation strategies, and emerging clinical potential as adjunct therapies for precision‐based asthma management.
Pulak Majumder, Trisita Majumder
wiley   +1 more source

Exploring the Antifungal Potential of the Brown Macroalga Hormophysa triquetra: Morphological Disruptions and Structural Changes in Plant Pathogens

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Extracts of Hormophysa triquetra showed antifungal activity with marked hyphal deformities in Fusarium oxysporum and Alternaria alternata. Light microscopy and SEM confirmed structural alterations despite unchanged radial growth. Cucumber assays validated reduced disease incidence, linked to fatty‐acid–rich metabolites detected by GC–MS.
Shazia Bibi, Samir Jaoua, Mohammad A. Al‐Ghouti, Nabil Zouari, Mohammed H. Abu‐Dieyeh   +4 more
wiley   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, Volume 59, Issue 6, June 2026.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

A study of the modulation of Toll-like receptor signalling in macrophages by Annexin-1

, 2010
PhDAnnexin-A1 (AnxA1) is an endogenous anti-inflammatory protein that has been shown to exert a protective role against the lethal effects induced by the Toll-like receptor (TLR) 4 agonist lipopolysaccharide (LPS).
Polycarpou, Anastasia
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