Results 131 to 140 of about 30,858,840 (226)

Serum Lipidomics Profiling Identify Novel Biomarkers of Distal Symmetrical Polyneuropathy in Type 1 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10670-10682, November 2026.
ABSTRACT Background Distal symmetrical polyneuropathy (DSPN) is a common complication of type 1 diabetes (T1D), yet validated biomarkers for early detection or prognosis are lacking. Metabolic disturbances driven by chronic hyperglycemia and dyslipidemia contribute to DSPN development and progression.
Tik Muk, Tina Okdahl, Marietta Kokla, Tommi Suvitaival, Gurjeet Kaur, Ismo M. Mattila, Simon M. Kienle, Christian Buhl, Knud Yderstræde, Troels S. Jensen, Peter Rossing, Flemming Pociot, Birgitte Brock, Cristina Legido‐Quigley, Páll Karlsson, Christian S. Hansen, Christina Brock, Joachim Størling, Karolina Sulek   +18 more
wiley   +1 more source

Anticorpos Anti-Receptor De Fosfolipase A2 Em Pacientes Brasileiros Com Glomerulopatias

, 2018
Introduction: Recently Great Progress Has Been Made In Understanding The Pathogenesis Of Membranous Glomerulopathy With The Discovery Of Antibodies Against The M-Type Receptor Of Phospholipase A2 (M-Type Phospholipase A2 Receptor, Pla2r) In Serum And ...
Santos Neto, Cicero De Oliveira [UNIFESP]
core  

The M-type receptor PLA2R regulates senescence through the p53 pathway.

, 2009
International audienceSenescence is a stable proliferative arrest induced by various stresses such as telomere erosion, oncogenic or oxidative stress. Compelling evidence suggests that it acts as a barrier against tumour development.
Bernard, David, Payré, Christine, De Launoit, Yvan, Gil, Jesus, Augert, Arnaud, Lambeau, Gérard, Jesus Gil, Gérard Lambeau, Arnaud Augert, Christine Payré, Yvan de Launoit, David Bernard   +11 more
core   +1 more source

Targeting CD20 in Primary Membranous Nephropathy Serologically and Histologically Negative for PLA2R: Is Obinutuzumab Superior to Rituximab?

Drug Design, Development and Therapy
Huiling Cao,1,* Yumei Feng,2,* Xueting Li,1 Ben Ke,1 Limin Gong3 1Department of Nephrology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China; 2Department of Emergency, Pingxiang ...
Cao H, Feng Y, Li X, Ke B, Gong L
doaj  

Spontaneous inferior epigastric artery hemorrhage in a COVID-19 patient with membranous nephropathy on anticoagulant therapy: a Case Report

Frontiers in Medicine
BackgroundThe management of Coronavirus disease 2019 (COVID-19) is complicated by coagulopathies that increase both thrombotic and hemorrhagic risks, particularly in patients with comorbidities such as membranous nephropathy (MN) who require ...
Nianzong Hou, Nianzong Hou, Guoxiang Xu, Lin Wang, Yun Zhang, Yong Yu, Lin Zhu, Weiwei Song, Rumin Zhang, Kai Wang   +9 more
doaj   +1 more source

Updates on intra‐articular corticosteroid administration in horses

Equine Veterinary Education, Volume 38, Issue 11, Page 600-610, November 2026.
Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner, L. Bass, C. Kawcak, L. V. Schnabel, K. L. Hallowell, L. M. Pezzanite   +5 more
wiley   +1 more source

Type II phospholipase A2 recombinant overexpression enhances stimulated arachidonic acid release.

, 1991
International audienceThe coding sequence of type II phospholipase A2 from human placenta was cloned in a bovine papilloma virus-derived eukaryotic expression vector under the control of the metallothionein promoter.
Pernas, P., Rybkine, T., Salvat, C., Bereziat, G., Masliah, J., Olivier, J. L.   +5 more
core   +1 more source

Epicardial adipose tissue‐linked leukotriene and cytokine signalling pathways – novel targets for prevention of obesity‐ and diabetes‐linked ventricular arrhythmia

The Journal of Physiology, EarlyView.
Kelly A. Aromolaran, Ademuyiwa S. Aromolaran   +1 more
wiley   +1 more source

Extracellular Vesicles in Dermatology: Where Are We and What Lies Ahead?

Experimental Dermatology, Volume 35, Issue 11, November 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as key players in skin biology, mediating intercellular communication across diverse physiological and pathological contexts. In this review, we critically assess the current understanding of EVs in dermatology, highlighting their roles in skin homeostasis, ageing, inflammation, wound healing and ...
Ines Martic, Alessandro Paolini, Stefania Paola Bruno, Andrea Gallego, Dorottya Ádám, Sedat Odabas, Şebnem Erçelen Ceylan, Emanuela Camera, Paloma Pérez, Attila Oláh, Andrea Masotti, Mirjana Nacka‐Aleksić, Danuta Gutowska‐Owsiak, Nsrein Ali, Maria Cavinato   +14 more
wiley   +1 more source

Natural Product‐Induced Ferroptosis to Overcome Therapy Resistance in Aggressive Cancers

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
Natural products trigger ferroptosis through iron overload, glutathione depletion, glutathione peroxidase 4 inhibition, and reactive oxygen species accumulation, selectively targeting aggressive, and drug‐resistant cancers. Polyphenols, alkaloids and terpenoids emerge as promising multi‐target agents to overcome therapy resistance and improve future ...
Giorgio Antoniolli
wiley   +1 more source