Results 111 to 120 of about 30,858,840 (226)
Frontiers in ImmunologyIntroductionMembranous nephropathy (MN) is a common cause of nephrotic syndrome (NS) in adults. Without treatment, two-thirds of patients with MN develop nonprogressive chronic kidney disease or end-stage renal disease within 10 years. Obinutuzumab (OBZ),
Jinmeng Wang +3 more
doaj +1 more source
Phospholipase A2 affects the activity of fusicoccin receptors
, 1993 Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised ...
Alessandro Ballio +20 more
core +1 more source
TMEM16A channel signalling microdomains in the regulation of vascular function
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
Progress of M-Type Phospholipase A2 Receptor in Membranous Nephropathy
Advances in Clinical Medicine, 2023 openaire +1 more source
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
The Journal of Physiology, EarlyView.Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source
Occurrence of the A2 matyng type and Self isolates of Phytophthora infestans in Italy [PDF]
, 1997 Among one hundred and sixty-four isolates of Phytophthora infestans collected during 1995-96 from different italian regions, 27 strains of mating type A2 e 7 strains of Self were identified. All the A2 and Self isolates from potato and tomato plants were
Cristinzio, Gennaro, Testa, Antonino
core +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
The Journal of Physiology, EarlyView.Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 21, 12 November 2026.In this review, we provide an overview of selected historical antidotes against snakebite envenomation used in early modern Europe. Then, the evidence‐based antivenom activity of some natural compounds is discussed as resulting from more than two decades of research studies.
Elisa Bianconi +3 more
wiley +1 more source
Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy
Advanced Therapeutics, Volume 9, Issue 11, November 2026.This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra +5 more
wiley +1 more source