Results 101 to 110 of about 26,727 (247)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Clinical, genetic and molecular aspects of membranous nephropathy

, 2011
Membranous Nephropathy (MN) is one of the leading causes of end-stage renal disease (ESRD). MN is an autoimmune disease in which autoantibodies target antigens at the level of the glomerular basement membrane.
Stanescu, H.C.
core  

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source

Upregulation of group IB secreted phospholipase A(2) and its M-type receptor in rat ANTI-THY-1 glomerulonephritis

, 2006
Treatment of rat glomerular mesangial cell (GMC) cultures with pancreatic secreted phospholipase A2 (sPLA2-IB) results in an enhanced expression of sPLA2-IIA and COX-2, possibly via binding to its specific M-type sPLA2 receptor.
Radeke, H.H., Radeke, H. H., U. Haas, J. Floege, H.H. Radeke, G. Lambeau, Beck, G., Thorwart, B., S. Beck, Flöge, Jürgen, Lambeau, G., Gurrieri, S., Floege, J., J. Pfeilschifter, Ostendorf, Tammo, Kaszkin, M., Ostendorf, T., T. Ostendorf, Nevalainen, T., T. Nevalainen, Beck, S., S. Gurrieri, Haas, U., M. Kaszkin, Pfeilschifter, J., B. Thorwart, G. Beck   +26 more
core   +1 more source

Association of M-Type Phospholipase A2 Receptor Deposition in Kidney Tissue with Treatment Outcomes in Patients with Idiopathic Membranous Nephropathy [Corrigendum]

Journal of Inflammation Research
Xie NQ, Zhang YL, Zheng ZL, Zheng QL, Chen RJ. J Inflamm Res. 2023;16:6319–6328. The authors have advised that they neglected to include a funding statement on page 6327 of the published paper.
Xie NQ, Zhang YL, Zheng ZL, Zheng QL, Chen RJ   +4 more
doaj  

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Phospholipase A2 affects the activity of fusicoccin receptors

, 1993
Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised ...
Fogliano, Vincenzo, Alessandro Ballio, Fullone, M. R, Fogliano, V, Vincenzo Fogliano, Maria Rosaria Fullone, Aducci, P, Donini, V, Virgilio Donini, V. Fogliano, Patrizia Aducci, Mauro Marra, M. Marra, Donini, Virgilio, Marra, Mauro, Ballio, A, P. Aducci, FULLONE, Maria Rosaria, Aducci, Patrizia, Ballio, Alessandro, V. Donini, Fullone, M.R, Marra, M, A. Ballio   +23 more
core   +1 more source

Obinutuzumab for treatment of membranous nephropathy in patients positive and negative for the phospholipase A2 receptor antibody: case reports

Frontiers in Immunology
IntroductionMembranous nephropathy (MN) is a common cause of nephrotic syndrome (NS) in adults. Without treatment, two-thirds of patients with MN develop nonprogressive chronic kidney disease or end-stage renal disease within 10 years. Obinutuzumab (OBZ),
Jinmeng Wang, Jinmeng Wang, Wenfeng Wu, Huiyi Wu   +3 more
doaj   +1 more source