Results 161 to 170 of about 26,727 (247)

Evidence‐Based Clinical Practice Guidelines for Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) 2026

Hepatology Research, Volume 56, Issue 6, Page 887-902, June 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, with an increasing number of patients progressing to cirrhosis and hepatocellular carcinoma (HCC). Early identification of individuals at high risk for advanced fibrosis is essential for preventing liver‐related ...
Norio Akuta, Tomomi Kogiso, Kenichi Ikejima, Motoyuki Otsuka, Takumi Kawaguchi, Miwa Kawanaka, Hirokazu Takahashi, Nobuharu Tamaki, Hayato Nakagawa, Hayato Hikita, Hideki Fujii, Kanji Yamaguchi, Masato Yoneda, Kazuyoshi Kon, Akira Uchiyama, Yuya Seko, Sadatsugu Sakane, Ryuta Shigefuku, Naoto Fujiwara, Michihiro Iwaki, Takashi Kobayashi, Takuya Adachi, Yasuto Takeuchi, Tsubasa Tsutsumi, Dan Nakano, Kaoru Shibayama, Noriyo Urata, Hisamitsu Miyaaki, Hidekatsu Kuroda, Masahiro Koseki, Hirohito Sone, Yasuhiro Matsubayashi, Keisuke Kakisaka, Atsushi Takai, Kazuo Notsumata, Masataka Seike, Yoshiyuki Takei, Yoshifumi Takeyama, Susumu Eguchi, Sumio Watanabe, Hajime Isomoto, Hiroshi Yotsuyanagi, Takao Itoi, Tetsuo Takehara, Satoshi Mochida   +44 more
wiley   +1 more source

The regulation of endocannabinoids after neuronal damage and the neuroprotective impact of GPR55 in organotypic hippocampal slice cultures

, 2013
Endocannabinoids (eCB) are signaling lipids and became known for their importance in the central nervous system as well as in immune defense. Beneficial effects of eCB are shown in processes of excitotoxic lesion, secondary damage and neuronal plasticity
Kallendrusch, Sonja
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Characterisation of PLD activity in real-time [PDF]

PLD catalyses hydrolysis of phosphatidylcholine (PtdCho) to produce phosphatidic acid (PtdOH) and choline. PtdOH is a second messenger responsible for a multitude of cell processes, ranging from cytoskeletal rearrangement to cell proliferation ...
Aletrari, Mina-Olga
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Quantitative detection and prognostic value of antibodies against M-type phospholipase A2 receptor and its cysteine-rich ricin domain and C-type lectin domains 1 and 6-7-8 in patients with idiopathic membranous nephropathy. [PDF]

PLoS One
Liu X, Xue J, Li T, Wu Q, Sheng H, Yang X, Lin B, Zhou X, Qin Y, Huang Z, Zhou L, Wang L, Hu Z, Huang B.   +13 more
europepmc   +1 more source

Maternal cardiometabolic dysfunction and fetal sex‐specific alterations to uterine vascular reactivity in an ovine model of obesity during pregnancy

The Journal of Physiology, Volume 604, Issue 12, Page 5011-5030, 15 June 2026.
Abstract figure legend We developed a novel ovine model of diet‐induced maternal obesity, where ewes were fed a control or obesogenic diet for 60 days pre‐pregnancy and throughout gestation. Pregnant ewes were surgically instrumented to assess maternal cardiovascular function near term.
Rachael C. Crew, Anna L. K. Cochrane, Youguo Niu, Sage G. Ford, Clement L. R. Cahen, Skaai H. Davison, Michael P. Murphy, Susan E. Ozanne, Dino A. Giussani   +8 more
wiley   +1 more source

High Relevance of Fatty Acid Oxidation in a Migrating Mammal, the Nathusius' Pipistrelle (Pipistrellus nathusii)

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Bats can sustain powered flight, but their reliance on fatty acid oxidation may limit long‐distance migration compared to birds. Using untargeted metabolomics, we analyzed blood metabolites of Nathusius' pipistrelle under controlled flight and migratory field conditions to identify fuel use.
Alesia Walker, Thuy Thanh Truong, Martin Klingenspor, Anders Hedenström, Gunars Pētersons, Philippe Schmitt‐Kopplin, Shannon E. Currie, Christian C. Voigt   +7 more
wiley   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, Volume 65, Issue 22, 25 May 2026.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

SP156AUTOANTIBODIES TO M-TYPE PHOSPHOLIPASE A2 RECEPTOR: INDIVIDUALIZED SEROLOGY-BASED APPROACH TO MEMBRANOUS NEPHROPATHY

Nephrology Dialysis Transplantation, 2019
Ekaterina Filatova, Patimat Kakhsurueva, Elena Kamyshova, Irina Gorelova, Alexey Borisov, Irina Bobkova   +5 more
openaire   +1 more source

Expression and significance of phospholipase A2 receptor and thrombospondin type-1 domain 7A in idiopathic membranous nephropathy

, 2019
Objective To investigate expression and significance of phospholipase A2 receptor(PLA2 R) and thrombospondin type-1 domain 7 A(THSD7 A) in idiopathic membranous nephropathy(IMN).
WANG Li-hua, LI Fei, WANG Chen, SHEN Ning-ning, HAO Min, GAO Li-fang, NIU Dan   +6 more
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Binding and internalization of extracellular type I phospholipase A2 in uterine stromal cells

, 1996
The cellular uptake of extracellular type-I phospholipase A2 (PLA2) was investigated in rat uterine stromal cells (UIII) in culture, which were found to express the high-affinity binding site for mammalian type-I PLA2, with a measured KD of 6.4 nM, a ...
TESSIER C., LAUGIER C., FAYARD J. M., ROSSINI, Gian Paolo   +3 more
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