Results 181 to 190 of about 30,858,840 (226)

Reevaluation of mycobacterial phosphatidyl-myo-inositol mannosides (PIMs) as Toll-like receptor 2 (TLR2) agonists. [PDF]

open access: yesJ Lipid Res
Belkai S   +13 more
europepmc   +1 more source

Anti-Contactin-1-Associated Membranous Nephropathy Presenting With Subsequent Autoimmune Nodopathy. [PDF]

open access: yesKidney Med
Visch R   +6 more
europepmc   +1 more source

Optimization of a Target Antigen Diagnostic Pathway for Membranous Nephropathy. [PDF]

open access: yesKidney Int Rep
Li W   +15 more
europepmc   +1 more source

Structure of Human M-Type Phospholipase A2 Receptor Revealed by Cryo-Electron Microscopy

Journal of Molecular Biology, 2017
M-type phospholipase A2 receptor (M-PLA2R) is a member of the mannose receptor family and known as the receptor of secretory phospholipase A2s. It has also been identified as the major autoantigen of idiopathic membranous nephropathy, one of the most common causes for nephrotic syndrome in adults.
Yongning He, Longxing Cao, Hua Tang
exaly   +3 more sources

Mapping the T cell epitopes of the M-type transmembrane phospholipase A2 receptor in primary membranous nephropathy

Kidney International, 2023
The M-type phospholipase A2 receptor (PLA2R) is the major autoantigen of primary membranous nephropathy (MN). Despite many studies on B-cell epitopes recognized by antibodies, little is known about T-cell epitopes. Herein, we synthesized 123 linear peptides, each consisting of 15-22 amino acids with 8-12 amino acid overlaps, across ten domains of PLA2R.
Xiao-Dan, Zhang   +10 more
openaire   +2 more sources

Crystal structure of the CTLD7 domain of human M-type phospholipase A2 receptor

Journal of Structural Biology, 2019
M-type phospholipase A2 receptor (PLA2R) is a member of the mannose receptor family. Recent evidence shows that PLA2R is a major autoantigen causing idiopathic membranous nephropathy (IMN), which is an autoimmune disease and one of the most common causes for nephrotic syndrome in adults. The epitope mapping data suggest that the major epitopes of PLA2R
Bowen Yu   +4 more
openaire   +2 more sources

Antibodies to m‐type phospholipase A2 receptor in children with idiopathic membranous nephropathy

Nephrology, 2015
AbstractIdiopathic membranous nephropathy (IMN), the commonest cause of adult nephrotic syndrome (NS), accounts for only a minority of paediatric NS. Antibodies to m‐type phospholipase A2 receptor (PLA2R) are seen in two‐thirds of adult IMN cases.
Vinod, Kumar   +8 more
openaire   +2 more sources

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