Results 201 to 210 of about 26,727 (247)

Secreted phospholipase A2 group X regulates peripheral sensitization to allergen. [PDF]

JCI Insight
Murphy RC, Lai Y, Chow YH, Liu M, Hondowicz BD, An D, Pepper M, Altemeier WA, Hallstrand TS.   +8 more
europepmc   +1 more source

First-line and Second-line Therapy of Zuberitamab in Idiopathic Membranous Nephropathy: A Single-center Retrospective Study. [PDF]

Kidney Med
Wang L, Yang M, Yan L, Shao F.
europepmc   +1 more source

β2-Integrins regulate dendritic cells through nuclear deformation and activation of phospholipase A2 and DNA damage-inducible GADD34. [PDF]

J Biol Chem
Somermäki R, Harjunpää H, Cui Y, Walander A, Fagerholm SC.   +4 more
europepmc   +1 more source

The value of proteinuria for the administration of rituximab in patients with PLA2R-associated membranous nephropathy: a single-centre retrospective analysis. [PDF]

Ann Med
Li X, Zhang Y, Xu C, Ke B.
europepmc   +1 more source

The Pivotal Role of Plant Derivatives and Eicosanoid Signaling Modulation in Counteracting Cardiomiopathy. [PDF]

Int J Mol Sci
Ussia S, Ritorto G, Macrì R, Serra M, Tavernese A, Altomare C, Dardano DM, Idone C, Palma E, Muscoli C, Volterrani M, Barillà F, Mollace V, Mollace R.   +13 more
europepmc   +1 more source

From Toxin to Therapy: Biomedical Applications of Bee Venom in Cancer, Diabetes, and Neurodegenerative Disorders. [PDF]

Int J Mol Sci
Lourenço KA, Dos Santos MV, Araujo AC, Guiguer EL, Curi R, Rocha MG, Monteiro ES, Yanaguizawa Junior JL, Pithon-Curi T, Quesada K, de Abreu LC, Marcondes CO, Barbalho SM, Valenti VE, Miglino MA.   +14 more
europepmc   +1 more source

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Structure of Human M-type Phospholipase A2 Receptor Revealed by Cryo-Electron Microscopy

Journal of Molecular Biology, 2017
M-type phospholipase A2 receptor (M-PLA2R) is a member of the mannose receptor family and known as the receptor of secretory phospholipase A2s. It has also been identified as the major autoantigen of idiopathic membranous nephropathy, one of the most common causes for nephrotic syndrome in adults.
Hua Tang, Yongning He
exaly   +3 more sources

Mapping the T cell epitopes of the M-type transmembrane phospholipase A2 receptor in primary membranous nephropathy

Kidney International, 2023
The M-type phospholipase A2 receptor (PLA2R) is the major autoantigen of primary membranous nephropathy (MN). Despite many studies on B-cell epitopes recognized by antibodies, little is known about T-cell epitopes. Herein, we synthesized 123 linear peptides, each consisting of 15-22 amino acids with 8-12 amino acid overlaps, across ten domains of PLA2R.
Xiao-Dan, Zhang, Cai-Xia, Lin, Zhao, Cui, Qiu-Hua, Gu, Bing-Jia, Yan, Lei, Liu, Wen-Chao, Song, Yi, Shi, Hanna, Debiec, Pierre, Ronco, Ming-Hui, Zhao   +10 more
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Crystal structure of the CTLD7 domain of human M-type phospholipase A2 receptor

Journal of Structural Biology, 2019
M-type phospholipase A2 receptor (PLA2R) is a member of the mannose receptor family. Recent evidence shows that PLA2R is a major autoantigen causing idiopathic membranous nephropathy (IMN), which is an autoimmune disease and one of the most common causes for nephrotic syndrome in adults. The epitope mapping data suggest that the major epitopes of PLA2R
Bowen Yu, Zhenzheng Hu, Dandan Kong, Chen Cheng, Yongning He   +4 more
openaire   +2 more sources